ID E6N4W9_CALS0 Unreviewed; 272 AA.
AC E6N4W9;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Large ribosomal subunit protein uL4 {ECO:0000256|HAMAP-Rule:MF_01328};
GN Name=rpl4 {ECO:0000256|HAMAP-Rule:MF_01328};
GN ORFNames=CSUB_C0304 {ECO:0000313|EMBL:BAJ50165.1}, HGMM_F27H06C07
GN {ECO:0000313|EMBL:BAJ47338.1}, HGMM_F51A06C03
GN {ECO:0000313|EMBL:BAJ49162.1};
OS Caldiarchaeum subterraneum.
OC Archaea; Nitrososphaerota; Candidatus Caldarchaeales;
OC Candidatus Caldarchaeaceae; Candidatus Caldarchaeum.
OX NCBI_TaxID=311458 {ECO:0000313|EMBL:BAJ47338.1, ECO:0000313|Proteomes:UP000008120};
RN [1] {ECO:0000313|EMBL:BAJ47338.1, ECO:0000313|Proteomes:UP000008120}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16309394; DOI=10.1111/j.1462-2920.2005.00881.x;
RA Nunoura T., Hirayama H., Takami H., Oida H., Nishi S., Shimamura S.,
RA Suzuki Y., Inagaki F., Takai K., Nealson K.H., Horikoshi K.;
RT "Genetic and functional properties of uncultivated thermophilic
RT crenarchaeotes from a subsurface gold mine as revealed by analysis of
RT genome fragments.";
RL Environ. Microbiol. 7:1967-1984(2005).
RN [2] {ECO:0000313|EMBL:BAJ47338.1, ECO:0000313|Proteomes:UP000008120}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21169198; DOI=10.1093/nar/gkq1228;
RA Nunoura T., Takaki Y., Kakuta J., Nishi S., Sugahara J., Kazama H.,
RA Chee G., Hattori M., Kanai A., Atomi H., Takai K., Takami H.;
RT "Insights into the evolution of Archaea and eukaryotic protein modifier
RT systems revealed by the genome of a novel archaeal group.";
RL Nucleic Acids Res. 39:3204-3223(2011).
CC -!- FUNCTION: Forms part of the polypeptide exit tunnel.
CC {ECO:0000256|HAMAP-Rule:MF_01328}.
CC -!- FUNCTION: One of the primary rRNA binding proteins, this protein
CC initially binds near the 5'-end of the 23S rRNA. It is important during
CC the early stages of 50S assembly. It makes multiple contacts with
CC different domains of the 23S rRNA in the assembled 50S subunit and
CC ribosome. {ECO:0000256|HAMAP-Rule:MF_01328}.
CC -!- SUBUNIT: Part of the 50S ribosomal subunit. {ECO:0000256|HAMAP-
CC Rule:MF_01328}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL4 family.
CC {ECO:0000256|ARBA:ARBA00010528, ECO:0000256|HAMAP-Rule:MF_01328}.
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DR EMBL; AP011834; BAJ47338.1; -; Genomic_DNA.
DR EMBL; AP011887; BAJ49162.1; -; Genomic_DNA.
DR EMBL; BA000048; BAJ50165.1; -; Genomic_DNA.
DR AlphaFoldDB; E6N4W9; -.
DR STRING; 311458.CSUB_C0304; -.
DR KEGG; csu:CSUB_C0304; -.
DR Proteomes; UP000008120; Chromosome.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.1370.10; -; 1.
DR HAMAP; MF_01328_A; Ribosomal_L4_A; 1.
DR InterPro; IPR002136; Ribosomal_uL4.
DR InterPro; IPR023574; Ribosomal_uL4_dom_sf.
DR InterPro; IPR045240; Ribosomal_uL4_euk/arch.
DR InterPro; IPR019970; Ribosomall_uL4-arc.
DR NCBIfam; TIGR03672; rpl4p_arch; 1.
DR PANTHER; PTHR19431; 60S RIBOSOMAL PROTEIN L4; 1.
DR PANTHER; PTHR19431:SF0; 60S RIBOSOMAL PROTEIN L4; 1.
DR Pfam; PF00573; Ribosomal_L4; 1.
DR SUPFAM; SSF52166; Ribosomal protein L4; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008120};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274, ECO:0000256|HAMAP-
KW Rule:MF_01328};
KW Ribosomal protein {ECO:0000256|ARBA:ARBA00022980, ECO:0000256|HAMAP-
KW Rule:MF_01328}; RNA-binding {ECO:0000256|HAMAP-Rule:MF_01328};
KW rRNA-binding {ECO:0000256|HAMAP-Rule:MF_01328}.
FT REGION 92..117
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 272 AA; 29414 MW; CBB79FCD727A53AA CRC64;
MNFTASLLLQ RPQQLTVNVY NLEGEAAETI TLPSIFSAPL REDLVSRAYI HLATHSLQPK
GASKMSGHKH SIESWGPGFG IARISRIKGR GTPKYGAGGM VPSAVGGRPT HPPTPEKKIH
KQINKKELRN ALLAALAFTA SPQHVKTRGH RITEQTLLPI IVDDGLEALS KTAEVRRVLI
KLGLGDELKR CGVKKVRAGK GKMRGRRYKR RKGPLIVVAA DRGVGKAASN IPGVEVVTAK
DLSVLHLAPG AKPGRLTLFT KSALKALEER LK
//
