ID E6N8V0_CALS0 Unreviewed; 461 AA.
AC E6N8V0;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE SubName: Full=Elongation factor EF-2 {ECO:0000313|EMBL:BAJ48719.1};
DE EC=3.6.5.3 {ECO:0000313|EMBL:BAJ48719.1};
DE Flags: Fragment;
GN ORFNames=HGMM_F40F12C44 {ECO:0000313|EMBL:BAJ48719.1};
OS Caldiarchaeum subterraneum.
OC Archaea; Nitrososphaerota; Candidatus Caldarchaeales;
OC Candidatus Caldarchaeaceae; Candidatus Caldarchaeum.
OX NCBI_TaxID=311458 {ECO:0000313|EMBL:BAJ48719.1, ECO:0000313|Proteomes:UP000008120};
RN [1] {ECO:0000313|EMBL:BAJ48719.1, ECO:0000313|Proteomes:UP000008120}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16309394; DOI=10.1111/j.1462-2920.2005.00881.x;
RA Nunoura T., Hirayama H., Takami H., Oida H., Nishi S., Shimamura S.,
RA Suzuki Y., Inagaki F., Takai K., Nealson K.H., Horikoshi K.;
RT "Genetic and functional properties of uncultivated thermophilic
RT crenarchaeotes from a subsurface gold mine as revealed by analysis of
RT genome fragments.";
RL Environ. Microbiol. 7:1967-1984(2005).
RN [2] {ECO:0000313|EMBL:BAJ48719.1, ECO:0000313|Proteomes:UP000008120}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21169198; DOI=10.1093/nar/gkq1228;
RA Nunoura T., Takaki Y., Kakuta J., Nishi S., Sugahara J., Kazama H.,
RA Chee G., Hattori M., Kanai A., Atomi H., Takai K., Takami H.;
RT "Insights into the evolution of Archaea and eukaryotic protein modifier
RT systems revealed by the genome of a novel archaeal group.";
RL Nucleic Acids Res. 39:3204-3223(2011).
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DR EMBL; AP011871; BAJ48719.1; -; Genomic_DNA.
DR AlphaFoldDB; E6N8V0; -.
DR Proteomes; UP000008120; Chromosome.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR CDD; cd01885; EF2; 1.
DR CDD; cd16268; EF2_II; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR041095; EFG_II.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR42908:SF3; ELONGATION FACTOR-LIKE GTPASE 1; 1.
DR PANTHER; PTHR42908; TRANSLATION ELONGATION FACTOR-RELATED; 1.
DR Pfam; PF14492; EFG_III; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Elongation factor {ECO:0000313|EMBL:BAJ48719.1};
KW Hydrolase {ECO:0000313|EMBL:BAJ48719.1};
KW Protein biosynthesis {ECO:0000313|EMBL:BAJ48719.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008120}.
FT DOMAIN 18..259
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT NON_TER 461
FT /evidence="ECO:0000313|EMBL:BAJ48719.1"
SQ SEQUENCE 461 AA; 50799 MW; D088140DC7E33407 CRC64;
MPRVKRISEV VDILRNKESI RNIGIIAHVD HGKTTTSDSL LAAAGLLSPS LAGRALALDY
LEEEQQRQMT IKAANVSLYY EMDGKPYIIN LIDTPGHVDF SGRVTRALRA IDGAIVVVDA
VEGVMTQTET VIRQALGERV RPVLYINKID RLVKELKLPP EKIQETLARI VREVNTLIDM
YGEPEQREKW KISFADNTVA IGSSKDRWGF TVKQAQQKGI KFSDVIDAFS REDVEWLRQK
TPLHEALLEM VISKHPPPHV AQKYRISKIW KGDLESEVGR AMLDCDENGP TVMAVTDVRV
DPQAGVVATG RLFSGTISEG DSVIIVGRNI SGRVQQVGVY MGPSREIVGS IPAGNIPAVL
GLADVRAGDT IGTVETVPFE SLKYVSEPVV TISVEPKYSR DLPKLVEFLN KLTIEDPTLV
TVVRPETGEY LISGMGTLHL EIALTWIQKA GLEVVSGRPI I
//
