ID E6N9G4_CALS0 Unreviewed; 683 AA.
AC E6N9G4;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=N-methylhydantoinase A {ECO:0000313|EMBL:BAJ48933.1};
DE EC=3.5.2.14 {ECO:0000313|EMBL:BAJ48933.1};
GN ORFNames=CSUB_C1703 {ECO:0000313|EMBL:BAJ51554.1}, HGMM_F28A10C24
GN {ECO:0000313|EMBL:BAJ48933.1};
OS Caldiarchaeum subterraneum.
OC Archaea; Nitrososphaerota; Candidatus Caldarchaeales;
OC Candidatus Caldarchaeaceae; Candidatus Caldarchaeum.
OX NCBI_TaxID=311458 {ECO:0000313|EMBL:BAJ48933.1, ECO:0000313|Proteomes:UP000008120};
RN [1] {ECO:0000313|EMBL:BAJ48933.1, ECO:0000313|Proteomes:UP000008120}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16309394; DOI=10.1111/j.1462-2920.2005.00881.x;
RA Nunoura T., Hirayama H., Takami H., Oida H., Nishi S., Shimamura S.,
RA Suzuki Y., Inagaki F., Takai K., Nealson K.H., Horikoshi K.;
RT "Genetic and functional properties of uncultivated thermophilic
RT crenarchaeotes from a subsurface gold mine as revealed by analysis of
RT genome fragments.";
RL Environ. Microbiol. 7:1967-1984(2005).
RN [2] {ECO:0000313|EMBL:BAJ48933.1, ECO:0000313|Proteomes:UP000008120}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21169198; DOI=10.1093/nar/gkq1228;
RA Nunoura T., Takaki Y., Kakuta J., Nishi S., Sugahara J., Kazama H.,
RA Chee G., Hattori M., Kanai A., Atomi H., Takai K., Takami H.;
RT "Insights into the evolution of Archaea and eukaryotic protein modifier
RT systems revealed by the genome of a novel archaeal group.";
RL Nucleic Acids Res. 39:3204-3223(2011).
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DR EMBL; AP011876; BAJ48933.1; -; Genomic_DNA.
DR EMBL; BA000048; BAJ51554.1; -; Genomic_DNA.
DR AlphaFoldDB; E6N9G4; -.
DR STRING; 311458.CSUB_C1703; -.
DR KEGG; csu:CSUB_C1703; -.
DR BioCyc; CCAL311458:G131R-1731-MONOMER; -.
DR Proteomes; UP000008120; Chromosome.
DR GO; GO:0047423; F:N-methylhydantoinase (ATP-hydrolyzing) activity; IEA:UniProtKB-EC.
DR Gene3D; 3.30.420.40; -; 1.
DR InterPro; IPR049517; ACX-like_C.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR008040; Hydant_A_N.
DR InterPro; IPR002821; Hydantoinase_A.
DR InterPro; IPR045079; Oxoprolinase_fam.
DR PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR PANTHER; PTHR11365:SF23; HYPOTHETICAL 5-OXOPROLINASE (EUROFUNG)-RELATED; 1.
DR Pfam; PF19278; Hydant_A_C; 1.
DR Pfam; PF05378; Hydant_A_N; 1.
DR Pfam; PF01968; Hydantoinase_A; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:BAJ48933.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008120}.
FT DOMAIN 7..183
FT /note="Hydantoinase/oxoprolinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF05378"
FT DOMAIN 204..498
FT /note="Hydantoinase A/oxoprolinase"
FT /evidence="ECO:0000259|Pfam:PF01968"
FT DOMAIN 514..678
FT /note="Acetophenone carboxylase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19278"
SQ SEQUENCE 683 AA; 74982 MW; 763379A9B994FAC5 CRC64;
MAKVVAAVDV GGTFTDLVAV DESDGRLYKV KTRSTPHRPE EGFLDAVQKL LENFSPKDFE
LIIHVNTIGT NLFRGQLALK MPAVSLVTTK GFRDVVEIGR QNRPELYNIF YRRPDPIVPR
ERRFEVSERV DGKGEVLKEV DERELEALAE QIEKIGTESV AICFLNSYLN PVNEKRAKEV
LRRCLNALIF TSYEVDPEHR EYERTSTTVV NAALAPVVSR YIASVRQGLD GLGITCPVQI
MSSAGGLVDV DEAVNRPVAC IESGPAAGVI GAAKVAEAIG LKRVISFDMG GTTAKTGVVV
DGLPATVPEI EVGGRVHMGR IIKGSGYPVR FPSIDLAEVS AGGGTIIQVS KTGGLQVGPL
SAGADPGPAC YGMGGVEPTI TDANHLLGRV EHLLGGEMKL DTVLAEKAME KVAKQLGQNL
VETSWNSLVL ANLHMARAVH IVTLERGLDP TEFTLVAFGG AGPMHAAELA QQIGISKIVI
PPSPGLFSSL GLLMTDMKYS YVRGYVKTLS KDDEQKIEQT YREIEEYAVG QLSRKVALKE
YRIVRTIDLR YLGQGYEIEV DAPRPFNIDE VFTKFEELHS STYGYKHVGE KIESTALRVY
IIIHTSRPSL PKTYDQRRYA AKRVRRVFFG EGFMDSPVLW REALETGYEA EGPLVIEEYD
STTVVPPGWS IHVEENGCMV MER
//
