ID E6QY71_CRYGW Unreviewed; 606 AA.
AC E6QY71;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Cytoplasm protein, putative {ECO:0000313|EMBL:ADV19779.1};
GN OrderedLocusNames=CGB_A6450W {ECO:0000313|EMBL:ADV19779.1};
OS Cryptococcus gattii serotype B (strain WM276 / ATCC MYA-4071)
OS (Filobasidiella gattii) (Cryptococcus bacillisporus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus gattii species complex.
OX NCBI_TaxID=367775 {ECO:0000313|EMBL:ADV19779.1, ECO:0000313|Proteomes:UP000007805};
RN [1] {ECO:0000313|EMBL:ADV19779.1, ECO:0000313|Proteomes:UP000007805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WM276 / ATCC MYA-4071 {ECO:0000313|Proteomes:UP000007805};
RX PubMed=21304167; DOI=10.1128/mBio.00342-10;
RA D'Souza C.A., Kronstad J.W., Taylor G., Warren R., Yuen M., Hu G.,
RA Jung W.H., Sham A., Kidd S.E., Tangen K., Lee N., Zeilmaker T., Sawkins J.,
RA McVicker G., Shah S., Gnerre S., Griggs A., Zeng Q., Bartlett K., Li W.,
RA Wang X., Heitman J., Stajich J.E., Fraser J.A., Meyer W., Carter D.,
RA Schein J., Krzywinski M., Kwon-Chung K.J., Varma A., Wang J., Brunham R.,
RA Fyfe M., Ouellette B.F., Siddiqui A., Marra M., Jones S., Holt R.,
RA Birren B.W., Galagan J.E., Cuomo C.A.;
RT "Genome variation in Cryptococcus gattii, an emerging pathogen of
RT immunocompetent hosts.";
RL MBio 2:E342-E342(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=WM276;
RA D'Souza C.A., Kronstad J.W., Taylor G., Warren R., Yuen M., Hu G.,
RA Jung W.H., Sham A., Kidd S.E., Tangen K., Lee N., Zeilmaker T., Sawkins J.,
RA McVicker G., Shah S., Gnerre S., Griggs A., Zeng Q., Bartlett K., Li W.,
RA Wang X., Heitman J., Stajich J.E., Fraser J.A., Meyer W., Carter D.,
RA Schein J., Krzywinski M., Kwong-Chung K.J., Varma A., Wang J., Brunham R.,
RA Fyfe M., Ouellette B.F.F., Siddiqui A., Marra M., Jones S., Holt R.,
RA Birren B.W., Galagan J.E., Cuomo C.A.;
RT "Genome variation in Cryptococcus gattii, an emerging pathogen of
RT immunocompetent hosts.";
RL MBio 0:0-0(2011).
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DR EMBL; CP000286; ADV19779.1; -; Genomic_DNA.
DR RefSeq; XP_003191566.1; XM_003191518.1.
DR AlphaFoldDB; E6QY71; -.
DR GeneID; 10188279; -.
DR KEGG; cgi:CGB_A6450W; -.
DR VEuPathDB; FungiDB:CGB_A6450W; -.
DR eggNOG; KOG0234; Eukaryota.
DR HOGENOM; CLU_006383_0_0_1; -.
DR OrthoDB; 2013830at2759; -.
DR Proteomes; UP000007805; Chromosome A.
DR GO; GO:0003873; F:6-phosphofructo-2-kinase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006003; P:fructose 2,6-bisphosphate metabolic process; IEA:InterPro.
DR GO; GO:0006000; P:fructose metabolic process; IEA:InterPro.
DR CDD; cd07067; HP_PGM_like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.1240; Phosphoglycerate mutase-like; 1.
DR InterPro; IPR003094; 6Pfruct_kin.
DR InterPro; IPR013079; 6Phosfructo_kin.
DR InterPro; IPR013078; His_Pase_superF_clade-1.
DR InterPro; IPR029033; His_PPase_superfam.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10606; 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE; 1.
DR PANTHER; PTHR10606:SF39; 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2,6-BISPHOSPHATASE YLR345W-RELATED; 1.
DR Pfam; PF01591; 6PF2K; 1.
DR Pfam; PF00300; His_Phos_1; 1.
DR PRINTS; PR00991; 6PFRUCTKNASE.
DR SMART; SM00855; PGAM; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53254; Phosphoglycerate mutase-like; 1.
PE 4: Predicted;
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 15..230
FT /note="6-phosphofructo-2-kinase"
FT /evidence="ECO:0000259|Pfam:PF01591"
FT REGION 480..501
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 528..606
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 579..598
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 606 AA; 67039 MW; C53A7765A144444E CRC64;
MAAPLYVTQS GRLWHAGLIL IVTVGLPARG KTHISRALER YLRWLGVKTR VYSIGDYRRK
VLGGAENVPH DYFQTKTPRS EATNALRRRI KTELEDQIMD FFAVQGGQVV IYDANNGSIA
ERKITSEKFG AKGVHVIYLE SLCDQEDIIT SNIRSVKLSS PDYAGWDAEK AVADYWERIR
DQAAVYDTVT ADEGPFIKVM NVGERIEVNR IEGYLQTRCC FFLMNIHTRP RTIYFARSGQ
SLIEHSYKAD SDLSPAGWEY AERLKAAVIA RRKALREERK SKGEVLGEEN PLLVWTSARR
RAYHTAWPFV HSGYKVVQKP IMSEINPGVW DGLSTQEAME LYPDEWSRFL ADPYAHRAPR
AESYHDLSVR LESVIFELER CQNDLLIIGH ASVIRCLLAY LVGLPPNEVP AVEIARGDLV
EITPASYGVI SRAWHFWSGE GRGDAYGENL YENFAEATSG KGSVLPDSGV NFAADALNME
KEAEEEEGRE KEKEKEMGKG GREAMMEAAM AVGKISEQAA ANSAAAAAGA EGGGGVGQGA
RGPGKALRRW GSEKGKGRGL PGLSELNEAE EAEEERGEQN DEGAVSEGEG KDGGKTRSRA
MSLLEI
//
