ID E6R1D6_CRYGW Unreviewed; 847 AA.
AC E6R1D6;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Adenosylmethionine-8-amino-7-oxononanoate transaminase, putative {ECO:0000313|EMBL:ADV20629.1};
GN OrderedLocusNames=CGB_B9110W {ECO:0000313|EMBL:ADV20629.1};
OS Cryptococcus gattii serotype B (strain WM276 / ATCC MYA-4071)
OS (Filobasidiella gattii) (Cryptococcus bacillisporus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus gattii species complex.
OX NCBI_TaxID=367775 {ECO:0000313|EMBL:ADV20629.1, ECO:0000313|Proteomes:UP000007805};
RN [1] {ECO:0000313|EMBL:ADV20629.1, ECO:0000313|Proteomes:UP000007805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WM276 / ATCC MYA-4071 {ECO:0000313|Proteomes:UP000007805};
RX PubMed=21304167; DOI=10.1128/mBio.00342-10;
RA D'Souza C.A., Kronstad J.W., Taylor G., Warren R., Yuen M., Hu G.,
RA Jung W.H., Sham A., Kidd S.E., Tangen K., Lee N., Zeilmaker T., Sawkins J.,
RA McVicker G., Shah S., Gnerre S., Griggs A., Zeng Q., Bartlett K., Li W.,
RA Wang X., Heitman J., Stajich J.E., Fraser J.A., Meyer W., Carter D.,
RA Schein J., Krzywinski M., Kwon-Chung K.J., Varma A., Wang J., Brunham R.,
RA Fyfe M., Ouellette B.F., Siddiqui A., Marra M., Jones S., Holt R.,
RA Birren B.W., Galagan J.E., Cuomo C.A.;
RT "Genome variation in Cryptococcus gattii, an emerging pathogen of
RT immunocompetent hosts.";
RL MBio 2:E342-E342(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=WM276;
RA D'Souza C.A., Kronstad J.W., Taylor G., Warren R., Yuen M., Hu G.,
RA Jung W.H., Sham A., Kidd S.E., Tangen K., Lee N., Zeilmaker T., Sawkins J.,
RA McVicker G., Shah S., Gnerre S., Griggs A., Zeng Q., Bartlett K., Li W.,
RA Wang X., Heitman J., Stajich J.E., Fraser J.A., Meyer W., Carter D.,
RA Schein J., Krzywinski M., Kwong-Chung K.J., Varma A., Wang J., Brunham R.,
RA Fyfe M., Ouellette B.F.F., Siddiqui A., Marra M., Jones S., Holt R.,
RA Birren B.W., Galagan J.E., Cuomo C.A.;
RT "Genome variation in Cryptococcus gattii, an emerging pathogen of
RT immunocompetent hosts.";
RL MBio 0:0-0(2011).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- PATHWAY: Cofactor biosynthesis; biotin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004746}.
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DR EMBL; CP000287; ADV20629.1; -; Genomic_DNA.
DR RefSeq; XP_003192416.1; XM_003192368.1.
DR AlphaFoldDB; E6R1D6; -.
DR GeneID; 10187922; -.
DR KEGG; cgi:CGB_B9110W; -.
DR VEuPathDB; FungiDB:CGB_B9110W; -.
DR eggNOG; KOG1401; Eukaryota.
DR HOGENOM; CLU_010794_0_0_1; -.
DR OrthoDB; 5487177at2759; -.
DR Proteomes; UP000007805; Chromosome B.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR GO; GO:1901564; P:organonitrogen compound metabolic process; IEA:UniProt.
DR CDD; cd03109; DTBS; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR005814; Aminotrans_3.
DR InterPro; IPR049704; Aminotrans_3_PPA_site.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR42684; ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE; 1.
DR PANTHER; PTHR42684:SF21; ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE; 1.
DR Pfam; PF13500; AAA_26; 1.
DR Pfam; PF00202; Aminotran_3; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00600; AA_TRANSFER_CLASS_3; 1.
PE 4: Predicted;
KW Aminotransferase {ECO:0000256|ARBA:ARBA00022576};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
SQ SEQUENCE 847 AA; 93270 MW; CC53010BC4CB8B51 CRC64;
MPLLFPHFRV HQVFGANTEV GKTLLTTALL RASASRYVSK SEESRKRVFY LKPVSTGPDS
ESDTSYVQRN TKPYSSYIST HNLYQYREPM SPHLAAQLAP ELPFPKTNEE LVRGIEAHAN
KCLQQLDGQD GCLFVETAGG VHSPALHLPH TQSTFLRSLR LPAVLVASPH LGGISTTVSA
YESLLLRGYS LSAVLCLHDS YYRNHTFLEE YFRDRGIGYW TIKPPPEKYG TVEEDGVRLE
QWYKEVEKSF EGEQGGGVGA AARWLEEGHK RRIEELAEMP QRTLDSVWWP FTQHQLINKK
EDVMVVDSAF GDNFDSYYAK PQSAPSSKNE SLLKSYFDGS ASWFTQSHGH ANEHLTLAAA
SAAGRYGHVL FPSGTNAPAL SLAEKLISTV GEGWASRVFY SDNGSTAMEV GLKMALRAAG
RRYGWDGEMG GDVGVIGLRG SYHGDTIGSM DATQASTFNK AVDWYKGRGH WFSPPVVQFV
NGAPTILTTG PDSWSPLPSS IASSSKSTRD GWALEFSSFK DVYEISSRSF SPLATYYRAH
IRSTLERLVR EGKKFGALVM EPTCLGAGGM VFVDPLFQSC MIEVVRASGD LFAGEKWDGG
SFEQELEGLK TRSGAEWQGL PVLYDEVFSG LHRFGYNSAA KVLGHTPDIS AYAKILTGGL
LPMSTTLASP SIFSAFLSPK KVDALLHGHS YTANPIGCAV ALEAMKLTTN YEAKGGWQGE
KNMWGVDKGA EGRWSFWKKE FVEDISRVEG VKGSMAMGTV FAIELQDDES DYSSHAALDF
LTTLRQVVVT PSSSHAAAED IVPFSPFQIH SRPLGNVVYI ITSLWTKPDV MRAMEKVILD
KLTKKAQ
//
