ID E6R4Z9_CRYGW Unreviewed; 621 AA.
AC E6R4Z9;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE RecName: Full=Ribitol kinase {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=CGB_D9090C {ECO:0000313|EMBL:ADV22225.1};
OS Cryptococcus gattii serotype B (strain WM276 / ATCC MYA-4071)
OS (Filobasidiella gattii) (Cryptococcus bacillisporus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus gattii species complex.
OX NCBI_TaxID=367775 {ECO:0000313|EMBL:ADV22225.1, ECO:0000313|Proteomes:UP000007805};
RN [1] {ECO:0000313|EMBL:ADV22225.1, ECO:0000313|Proteomes:UP000007805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WM276 / ATCC MYA-4071 {ECO:0000313|Proteomes:UP000007805};
RX PubMed=21304167; DOI=10.1128/mBio.00342-10;
RA D'Souza C.A., Kronstad J.W., Taylor G., Warren R., Yuen M., Hu G.,
RA Jung W.H., Sham A., Kidd S.E., Tangen K., Lee N., Zeilmaker T., Sawkins J.,
RA McVicker G., Shah S., Gnerre S., Griggs A., Zeng Q., Bartlett K., Li W.,
RA Wang X., Heitman J., Stajich J.E., Fraser J.A., Meyer W., Carter D.,
RA Schein J., Krzywinski M., Kwon-Chung K.J., Varma A., Wang J., Brunham R.,
RA Fyfe M., Ouellette B.F., Siddiqui A., Marra M., Jones S., Holt R.,
RA Birren B.W., Galagan J.E., Cuomo C.A.;
RT "Genome variation in Cryptococcus gattii, an emerging pathogen of
RT immunocompetent hosts.";
RL MBio 2:E342-E342(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=WM276;
RA D'Souza C.A., Kronstad J.W., Taylor G., Warren R., Yuen M., Hu G.,
RA Jung W.H., Sham A., Kidd S.E., Tangen K., Lee N., Zeilmaker T., Sawkins J.,
RA McVicker G., Shah S., Gnerre S., Griggs A., Zeng Q., Bartlett K., Li W.,
RA Wang X., Heitman J., Stajich J.E., Fraser J.A., Meyer W., Carter D.,
RA Schein J., Krzywinski M., Kwong-Chung K.J., Varma A., Wang J., Brunham R.,
RA Fyfe M., Ouellette B.F.F., Siddiqui A., Marra M., Jones S., Holt R.,
RA Birren B.W., Galagan J.E., Cuomo C.A.;
RT "Genome variation in Cryptococcus gattii, an emerging pathogen of
RT immunocompetent hosts.";
RL MBio 0:0-0(2011).
CC -!- SIMILARITY: Belongs to the FGGY kinase family.
CC {ECO:0000256|ARBA:ARBA00009156}.
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DR EMBL; CP000289; ADV22225.1; -; Genomic_DNA.
DR RefSeq; XP_003194012.1; XM_003193964.1.
DR AlphaFoldDB; E6R4Z9; -.
DR GeneID; 10189775; -.
DR KEGG; cgi:CGB_D9090C; -.
DR VEuPathDB; FungiDB:CGB_D9090C; -.
DR eggNOG; KOG2517; Eukaryota.
DR HOGENOM; CLU_009281_10_1_1; -.
DR OrthoDB; 120218at2759; -.
DR Proteomes; UP000007805; Chromosome D.
DR GO; GO:0016301; F:kinase activity; IEA:InterPro.
DR GO; GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd07782; FGGY_YpCarbK_like; 1.
DR Gene3D; 1.20.58.2240; -; 1.
DR Gene3D; 3.30.420.40; -; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR018485; FGGY_C.
DR InterPro; IPR018484; FGGY_N.
DR InterPro; IPR006003; FGGY_RbtK-like.
DR NCBIfam; TIGR01315; 5C_CHO_kinase; 1.
DR PANTHER; PTHR43435:SF4; FGGY CARBOHYDRATE KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43435; RIBULOKINASE; 1.
DR Pfam; PF02782; FGGY_C; 1.
DR Pfam; PF00370; FGGY_N; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE 3: Inferred from homology;
FT DOMAIN 6..99
FT /note="Carbohydrate kinase FGGY N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00370"
FT DOMAIN 323..534
FT /note="Carbohydrate kinase FGGY C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02782"
SQ SEQUENCE 621 AA; 68044 MW; 84DC584D17238A4C CRC64;
MSDMEYFIGF DVGTGSGRAC LVDRNGNLIA EHAEPTLTHR SPTDARIFEQ STRNIWKSLS
ICSKRILAES GVKPEQVKGL GFDATCSLAV VDKQGKPMSI SRTGQSEEDE KDANIGLDGE
WNVILWADHR AEEEAEKINS TGEGVLGFVG KTMSLEMEIP KTLWLSKHMA HERFKQCMFF
DLPDFLTYHA TSDRARSTCS LACKCSFVPI GATMTHDCDG GKEETSTQGW SARFFEKIGL
HDLVEEDFAS LGGIPGKNGL VLTAGQPVGK GLSKPAAEDL GLLEGTAVGS GVIDAYAGWI
GTVAAAAGED QAQPTLEDAS ARLAAIAGTS TCHIAQSKNG ILVPGVWGPY RDAVFPNLWM
NEGGQSSTGQ LIDFMMQSHP AYPKLLELSQ SSGKSTFELL AERLETLQKE KGAKTLTHLT
KDLHFYPDLH GNRSPLADPR MKGMITGLVL DDSLNDLAAK FNVTLEAIAL QTRHIVDEMN
AKGHKIDSIY MSGSQAKNGP LMRLLATVLQ MPVIIPPQPS AAVVLGAAML GRYAYDLMTE
RHGKPISSQQ EAEEAKEKDG WRLWDVMVQM TRPGKRIEPR NDKFGASEKR LLDVKYKIFR
EAVEVQRKWR QMIADEVKDE E
//
