ID E6R7C6_CRYGW Unreviewed; 533 AA.
AC E6R7C6;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 22-FEB-2023, entry version 49.
DE RecName: Full=Copper transport protein 86 {ECO:0000256|ARBA:ARBA00022406};
GN OrderedLocusNames=CGB_E5090C {ECO:0000313|EMBL:ADV22671.1};
OS Cryptococcus gattii serotype B (strain WM276 / ATCC MYA-4071)
OS (Filobasidiella gattii) (Cryptococcus bacillisporus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus gattii species complex.
OX NCBI_TaxID=367775 {ECO:0000313|EMBL:ADV22671.1, ECO:0000313|Proteomes:UP000007805};
RN [1] {ECO:0000313|EMBL:ADV22671.1, ECO:0000313|Proteomes:UP000007805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WM276 / ATCC MYA-4071 {ECO:0000313|Proteomes:UP000007805};
RX PubMed=21304167; DOI=10.1128/mBio.00342-10;
RA D'Souza C.A., Kronstad J.W., Taylor G., Warren R., Yuen M., Hu G.,
RA Jung W.H., Sham A., Kidd S.E., Tangen K., Lee N., Zeilmaker T., Sawkins J.,
RA McVicker G., Shah S., Gnerre S., Griggs A., Zeng Q., Bartlett K., Li W.,
RA Wang X., Heitman J., Stajich J.E., Fraser J.A., Meyer W., Carter D.,
RA Schein J., Krzywinski M., Kwon-Chung K.J., Varma A., Wang J., Brunham R.,
RA Fyfe M., Ouellette B.F., Siddiqui A., Marra M., Jones S., Holt R.,
RA Birren B.W., Galagan J.E., Cuomo C.A.;
RT "Genome variation in Cryptococcus gattii, an emerging pathogen of
RT immunocompetent hosts.";
RL MBio 2:E342-E342(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=WM276;
RA D'Souza C.A., Kronstad J.W., Taylor G., Warren R., Yuen M., Hu G.,
RA Jung W.H., Sham A., Kidd S.E., Tangen K., Lee N., Zeilmaker T., Sawkins J.,
RA McVicker G., Shah S., Gnerre S., Griggs A., Zeng Q., Bartlett K., Li W.,
RA Wang X., Heitman J., Stajich J.E., Fraser J.A., Meyer W., Carter D.,
RA Schein J., Krzywinski M., Kwong-Chung K.J., Varma A., Wang J., Brunham R.,
RA Fyfe M., Ouellette B.F.F., Siddiqui A., Marra M., Jones S., Holt R.,
RA Birren B.W., Galagan J.E., Cuomo C.A.;
RT "Genome variation in Cryptococcus gattii, an emerging pathogen of
RT immunocompetent hosts.";
RL MBio 0:0-0(2011).
CC -!- FUNCTION: Essential protein which may be involved in threonine
CC biosynthesis. {ECO:0000256|ARBA:ARBA00002048}.
CC -!- SIMILARITY: Belongs to the CTR86 family.
CC {ECO:0000256|ARBA:ARBA00007516}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000290; ADV22671.1; -; Genomic_DNA.
DR RefSeq; XP_003194458.1; XM_003194410.1.
DR AlphaFoldDB; E6R7C6; -.
DR GeneID; 10190715; -.
DR KEGG; cgi:CGB_E5090C; -.
DR VEuPathDB; FungiDB:CGB_E5090C; -.
DR eggNOG; KOG2676; Eukaryota.
DR HOGENOM; CLU_039868_0_0_1; -.
DR OrthoDB; 1438872at2759; -.
DR Proteomes; UP000007805; Chromosome E.
DR GO; GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR019156; Ataxin-10_domain.
DR PANTHER; PTHR13255; ATAXIN-10; 1.
DR PANTHER; PTHR13255:SF0; ATAXIN-10; 1.
DR Pfam; PF09759; Atx10homo_assoc; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022697};
KW Threonine biosynthesis {ECO:0000256|ARBA:ARBA00022697}.
FT DOMAIN 432..510
FT /note="Ataxin-10"
FT /evidence="ECO:0000259|Pfam:PF09759"
SQ SEQUENCE 533 AA; 59409 MW; 5499A81D6D052EC0 CRC64;
MKQLGALNPR LLANDLESDE LCLEGASNCE GIARYLAGHL NERTDILEQE EAEGFFQGLG
QVWTSLATSF DPSAKDMSRY ASEDSRIQLA LGLAKMERNL VAGLLPFQSE AFKHEPEIRR
LIFNITTFVR IEDCRFFAIH AIATQLLSNV LAPVNSSVAA TRHADAALRI YMSGNREDDI
IIRLFDSRDP KTNHATLHLL NNLTRNSLPR LEMLLTPTGI KWLARLLGRM DEWLDKEDNC
FDLTASIFTS IISFSLHPRL FQLLSEPSEP ITPSQTVLLK ILDSTLSSLP ASSPSPPVEN
YPNSFLHPLF NNLIQPSLPS LTQKADDPRL PKYLEGLVLV SEALGTIGLR VQERIDKATA
PGADREDVEL QMQGGEEQLV KVIKEPQSGI VRPLIDMLRA LNDYFPRTNP RNPSPPTNTT
AVPPELKPFS DLKRDLVRLL GVLTFSDSRV GDQVRECEGV QLVLSLTEID EGNPFLREHA
LFCVRNLMLN NPANQAIIKE MDPIGVLSET GELLPVPEKM KKKSIEATIA EEK
//
