ID E6R924_CRYGW Unreviewed; 1026 AA.
AC E6R924;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 22-FEB-2023, entry version 53.
DE RecName: Full=Dilute domain-containing protein {ECO:0000259|PROSITE:PS51126};
GN OrderedLocusNames=CGB_G1270C {ECO:0000313|EMBL:ADV23353.1};
OS Cryptococcus gattii serotype B (strain WM276 / ATCC MYA-4071)
OS (Filobasidiella gattii) (Cryptococcus bacillisporus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Cryptococcus;
OC Cryptococcus gattii species complex.
OX NCBI_TaxID=367775 {ECO:0000313|EMBL:ADV23353.1, ECO:0000313|Proteomes:UP000007805};
RN [1] {ECO:0000313|EMBL:ADV23353.1, ECO:0000313|Proteomes:UP000007805}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WM276 / ATCC MYA-4071 {ECO:0000313|Proteomes:UP000007805};
RX PubMed=21304167; DOI=10.1128/mBio.00342-10;
RA D'Souza C.A., Kronstad J.W., Taylor G., Warren R., Yuen M., Hu G.,
RA Jung W.H., Sham A., Kidd S.E., Tangen K., Lee N., Zeilmaker T., Sawkins J.,
RA McVicker G., Shah S., Gnerre S., Griggs A., Zeng Q., Bartlett K., Li W.,
RA Wang X., Heitman J., Stajich J.E., Fraser J.A., Meyer W., Carter D.,
RA Schein J., Krzywinski M., Kwon-Chung K.J., Varma A., Wang J., Brunham R.,
RA Fyfe M., Ouellette B.F., Siddiqui A., Marra M., Jones S., Holt R.,
RA Birren B.W., Galagan J.E., Cuomo C.A.;
RT "Genome variation in Cryptococcus gattii, an emerging pathogen of
RT immunocompetent hosts.";
RL MBio 2:E342-E342(2011).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=WM276;
RA D'Souza C.A., Kronstad J.W., Taylor G., Warren R., Yuen M., Hu G.,
RA Jung W.H., Sham A., Kidd S.E., Tangen K., Lee N., Zeilmaker T., Sawkins J.,
RA McVicker G., Shah S., Gnerre S., Griggs A., Zeng Q., Bartlett K., Li W.,
RA Wang X., Heitman J., Stajich J.E., Fraser J.A., Meyer W., Carter D.,
RA Schein J., Krzywinski M., Kwong-Chung K.J., Varma A., Wang J., Brunham R.,
RA Fyfe M., Ouellette B.F.F., Siddiqui A., Marra M., Jones S., Holt R.,
RA Birren B.W., Galagan J.E., Cuomo C.A.;
RT "Genome variation in Cryptococcus gattii, an emerging pathogen of
RT immunocompetent hosts.";
RL MBio 0:0-0(2011).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000292; ADV23353.1; -; Genomic_DNA.
DR RefSeq; XP_003195140.1; XM_003195092.1.
DR AlphaFoldDB; E6R924; -.
DR GeneID; 10188953; -.
DR KEGG; cgi:CGB_G1270C; -.
DR VEuPathDB; FungiDB:CGB_G1270C; -.
DR eggNOG; ENOG502QRMC; Eukaryota.
DR HOGENOM; CLU_006124_0_0_1; -.
DR OrthoDB; 1359946at2759; -.
DR Proteomes; UP000007805; Chromosome G.
DR CDD; cd15473; Myo5p-like_CBD_DIL_ANK; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR002710; Dilute_dom.
DR InterPro; IPR037986; Myo5p-like_CBD_DIL.
DR PANTHER; PTHR16027; DILUTE DOMAIN-CONTAINING PROTEIN YPR089W; 1.
DR PANTHER; PTHR16027:SF6; DILUTE DOMAIN-CONTAINING PROTEIN YPR089W; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF01843; DIL; 1.
DR SMART; SM00248; ANK; 3.
DR SMART; SM01132; DIL; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
DR PROSITE; PS51126; DILUTE; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023}.
FT REPEAT 214..246
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 446..685
FT /note="Dilute"
FT /evidence="ECO:0000259|PROSITE:PS51126"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 54..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 344..380
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 853..905
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 979..1026
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 56..70
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 344..361
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 362..380
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 982..1004
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1026 AA; 115379 MW; D12AF34D87C6C8E8 CRC64;
MSNPPTPKLA SLITSNIPSP SGLSTPTFGT GSQVGYGGET PHMLQRAIMQ GDDVPESPVI
DRDAGTDSPD AHGDHGAFAG PSRSFRKAPT PLFLNDPSPQ TILPLLEEEE VAQELCENVD
EDRELRTTLI LRHALQWGIE RGDVELVNWL VSLNGRWRSI LDREVQDLED EEGWGIVCMA
IHHSCGRQDR EEIVRAAVSR WGVSAGPRGG RDRRGWTPLH LAVLVSTPPL ISFLLSHGAS
PHLLTNRGLT PLDLVADIPG REAITLFLEH AISVPHPSSP LTSTIFIPKL PPARQKMLRK
RRRRARGHLE KMEEQERKEK IRIERAKWIA EKLKVVEVPP ELVFGKDENP KRNKEDMGGS
GLEEDDVNNE EDDDAEEEDE MNPASIANML VFSLVNLPEI FDILISNYEP VSQPLSKRTL
PANVLCYYAR FAYHMCEETW LETLIEGAIE RIEEGVYENM ENLAYLAFWA YNSCVLLHHL
RADEALQEAC DELGLLAILE ELVNAIHVFV IRIAERRIDT VLDTAILDYE TLDDFNDIRF
EGEWSLFRSF LYEVNPALIV QTFSQIYFWI ACELFNRILT RRKYLCRSKA LQIRVNLTFL
DDWVRVNGLP AQTSARHFAS LSQLLQWLQC LSQITEFDTL IGTMQNMKAI NPLQMRRAVR
EYRYEVNEGR MSDECAQYLA QLQKDWEKRR VQLSMQEAEH RKSASEWSEG TYGPGMLGSS
GYEESAMLID VLFDGSTTLT DFVPHSAPES LGELLDSRYM LPFLLPEDNI YLIATPPTDA
AYANLHIPSS SPFVTDTPIK RPLSHASYSS SRPMGYKIPN IGRLRDLPSD FFKWMKEKET
ELKLGREALR VEKRAAPTLS HPLGTNQKAK DTTPVRPPPE DKINLTPTRT PTSNRRKSGV
LAPPLPVEGA ELSTTLSILY PSTPTKLGAS LPSPGLRSSA SMNELREKKL AERPFEDIQE
EASSHIKPES YEMRMRTEML RENSGESVSS SGSKLSNGSA ASGGSGTKRW WRMSKGGEIP
SPGVND
//
