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Database: UniProt
Entry: E6RFN6_CRYGW
LinkDB: E6RFN6_CRYGW
Original site: E6RFN6_CRYGW 
ID   E6RFN6_CRYGW            Unreviewed;       574 AA.
AC   E6RFN6;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   08-MAR-2011, sequence version 1.
DT   16-JAN-2019, entry version 35.
DE   SubName: Full=Uracil permease {ECO:0000313|EMBL:ADV25840.1};
GN   OrderedLocusNames=CGB_N3370C {ECO:0000313|EMBL:ADV25840.1};
OS   Cryptococcus gattii serotype B (strain WM276 / ATCC MYA-4071)
OS   (Filobasidiella gattii) (Cryptococcus bacillisporus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina;
OC   Tremellomycetes; Tremellales; Cryptococcaceae; Cryptococcus;
OC   Cryptococcus gattii species complex.
OX   NCBI_TaxID=367775 {ECO:0000313|EMBL:ADV25840.1, ECO:0000313|Proteomes:UP000007805};
RN   [1] {ECO:0000313|EMBL:ADV25840.1, ECO:0000313|Proteomes:UP000007805}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WM276 / ATCC MYA-4071 {ECO:0000313|Proteomes:UP000007805};
RX   PubMed=21304167; DOI=10.1128/mBio.00342-10;
RA   D'Souza C.A., Kronstad J.W., Taylor G., Warren R., Yuen M., Hu G.,
RA   Jung W.H., Sham A., Kidd S.E., Tangen K., Lee N., Zeilmaker T.,
RA   Sawkins J., McVicker G., Shah S., Gnerre S., Griggs A., Zeng Q.,
RA   Bartlett K., Li W., Wang X., Heitman J., Stajich J.E., Fraser J.A.,
RA   Meyer W., Carter D., Schein J., Krzywinski M., Kwon-Chung K.J.,
RA   Varma A., Wang J., Brunham R., Fyfe M., Ouellette B.F., Siddiqui A.,
RA   Marra M., Jones S., Holt R., Birren B.W., Galagan J.E., Cuomo C.A.;
RT   "Genome variation in Cryptococcus gattii, an emerging pathogen of
RT   immunocompetent hosts.";
RL   MBio 2:E342-E342(2011).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=WM276;
RA   D'Souza C.A., Kronstad J.W., Taylor G., Warren R., Yuen M., Hu G.,
RA   Jung W.H., Sham A., Kidd S.E., Tangen K., Lee N., Zeilmaker T.,
RA   Sawkins J., McVicker G., Shah S., Gnerre S., Griggs A., Zeng Q.,
RA   Bartlett K., Li W., Wang X., Heitman J., Stajich J.E., Fraser J.A.,
RA   Meyer W., Carter D., Schein J., Krzywinski M., Kwong-Chung K.J.,
RA   Varma A., Wang J., Brunham R., Fyfe M., Ouellette B.F.F., Siddiqui A.,
RA   Marra M., Jones S., Holt R., Birren B.W., Galagan J.E., Cuomo C.A.;
RT   "Genome variation in Cryptococcus gattii, an emerging pathogen of
RT   immunocompetent hosts.";
RL   MBio 0:0-0(2011).
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DR   EMBL; CP000299; ADV25840.1; -; Genomic_DNA.
DR   RefSeq; XP_003197627.1; XM_003197579.1.
DR   STRING; 367775.XP_003197627.1; -.
DR   EnsemblFungi; ADV25840; ADV25840; CGB_N3370C.
DR   GeneID; 10186710; -.
DR   KEGG; cgi:CGB_N3370C; -.
DR   EuPathDB; FungiDB:CGB_N3370C; -.
DR   eggNOG; KOG2466; Eukaryota.
DR   eggNOG; COG1953; LUCA.
DR   KO; K03457; -.
DR   Proteomes; UP000007805; Chromosome N.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.10.4160.10; -; 1.
DR   InterPro; IPR001248; Pur-cyt_permease.
DR   InterPro; IPR038271; Pur-cyt_permease_sf.
DR   Pfam; PF02133; Transp_cyt_pur; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000007805};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007805};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     38     58       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     70     90       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    167    187       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    199    216       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    236    254       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    275    295       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    325    347       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    367    384       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    390    414       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    434    456       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    476    495       Helical. {ECO:0000256|SAM:Phobius}.
SQ   SEQUENCE   574 AA;  63900 MW;  57878BCE948AEB68 CRC64;
     MPIRRIRMPK LVVEGSKGRE AALENHDLLP IPLERRTWNF TTFSIFWFSA VGTVANWLSG
     GTFLSYGITV WDGILCNFFG YLLISFFMVI NGRAGSVYHI GFPVYCRSSF GVFGSFWPVF
     NRALSACVWN GVNTVTGGQC IYIFLHSIFP SIAHLPNHMP TTSGMTSAQM CGFFLFWFFT
     GCALFLSVPK WKLLIHAKLV AYFLSCVGML ALALTTSKGV GNTLTAGPTV HGSERAWLIV
     RFTLLSAAGC STFASNASDW QRNATHRRDP IFGQIFGFPM SNFITTLCGL IVAASSEKAY
     GTLIWNPLTY LDRILTENYD AKTRAGTAII SIGFAYSALF SCVFENVLPA GNDISSLAPK
     YLSMKRAFAI CMIITVVICP WYLLGSAGIF VTFISSYQIF LFSIVGILLV DYYIISKGRL
     DLTWMYTADK KGPYYYTFGI NWRAILAYFI GAGVNFAGFL NSMGVKGLST GVVRSFYFAF
     ITTGCASGLS YYLLARFFPQ ENYKRFKGLM FREWTEEEVE LYVQGAPWRI LETAPPEVGM
     DGVPIMPGSR ISLENVEDMD EKKVDTTHTT VLEA
//
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