ID E6SPV6_BACT6 Unreviewed; 672 AA.
AC E6SPV6;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Protein-disulfide reductase {ECO:0000313|EMBL:ADV44935.1};
DE EC=1.8.1.8 {ECO:0000313|EMBL:ADV44935.1};
GN OrderedLocusNames=Bache_3003 {ECO:0000313|EMBL:ADV44935.1};
OS Bacteroides helcogenes (strain ATCC 35417 / DSM 20613 / JCM 6297 / CCUG
OS 15421 / P 36-108).
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=693979 {ECO:0000313|EMBL:ADV44935.1, ECO:0000313|Proteomes:UP000008630};
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=P 36-108;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S.,
RA Kyrpides N., Mavromatis K., Ivanova N., Zeytun A., Brettin T., Detter J.C.,
RA Tapia R., Han C., Land M., Hauser L., Markowitz V., Cheng J.-F.,
RA Hugenholtz P., Woyke T., Wu D., Gronow S., Wellnitz S., Brambilla E.,
RA Klenk H.-P., Eisen J.A.;
RT "The complete genome of Bacteroides helcogenes P 36-108.";
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADV44935.1, ECO:0000313|Proteomes:UP000008630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35417 / DSM 20613 / JCM 6297 / CCUG 15421 / P 36-108
RC {ECO:0000313|Proteomes:UP000008630};
RX PubMed=21475586; DOI=10.4056/sigs.1513795;
RA Pati A., Gronow S., Zeytun A., Lapidus A., Nolan M., Hammon N.,
RA Deshpande S., Cheng J.F., Tapia R., Han C., Goodwin L., Pitluck S.,
RA Liolios K., Pagani I., Ivanova N., Mavromatis K., Chen A., Palaniappan K.,
RA Land M., Hauser L., Chang Y.J., Jeffries C.D., Detter J.C., Brambilla E.,
RA Rohde M., Goker M., Woyke T., Bristow J., Eisen J.A., Markowitz V.,
RA Hugenholtz P., Kyrpides N.C., Klenk H.P., Lucas S.;
RT "Complete genome sequence of Bacteroides helcogenes type strain (P 36-
RT 108).";
RL Stand. Genomic Sci. 4:45-53(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP002352; ADV44935.1; -; Genomic_DNA.
DR RefSeq; WP_013548522.1; NC_014933.1.
DR AlphaFoldDB; E6SPV6; -.
DR STRING; 693979.Bache_3003; -.
DR KEGG; bhl:Bache_3003; -.
DR PATRIC; fig|693979.3.peg.3146; -.
DR eggNOG; COG4232; Bacteria.
DR HOGENOM; CLU_015841_0_0_10; -.
DR OrthoDB; 9811036at2; -.
DR Proteomes; UP000008630; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0047134; F:protein-disulfide reductase (NAD(P)) activity; IEA:UniProtKB-EC.
DR GO; GO:0017004; P:cytochrome complex assembly; IEA:InterPro.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR Gene3D; 2.60.40.1250; Thiol:disulfide interchange protein DsbD, N-terminal domain; 1.
DR InterPro; IPR003834; Cyt_c_assmbl_TM_dom.
DR InterPro; IPR028250; DsbDN.
DR InterPro; IPR036929; DsbDN_sf.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR013766; Thioredoxin_domain.
DR PANTHER; PTHR32234:SF3; SUPPRESSION OF COPPER SENSITIVITY PROTEIN; 1.
DR PANTHER; PTHR32234; THIOL:DISULFIDE INTERCHANGE PROTEIN DSBD; 1.
DR Pfam; PF02683; DsbD; 1.
DR Pfam; PF11412; DsbD_N; 1.
DR Pfam; PF13899; Thioredoxin_7; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS51352; THIOREDOXIN_2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000313|EMBL:ADV44935.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008630};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..672
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003209284"
FT TRANSMEM 219..243
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 264..286
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 340..368
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 380..400
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 412..430
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 450..466
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 486..505
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 508..666
FT /note="Thioredoxin"
FT /evidence="ECO:0000259|PROSITE:PS51352"
SQ SEQUENCE 672 AA; 74078 MW; 05030C477975DE87 CRC64;
MKKSIFSVLL LLLTMVAQAQ IHEPVKFKSE LKTLSAGEAE VVFSATIEKG WHVYSTDLGD
GGPISATFNV DKLSGAELLG KLKPMGKEIA SFDKLFEMKV RYFENTAKFV QKIKLIGGTY
QIEGYLEYGA CNDENCLPPT QVPFKLSGKG EGTARAGGAE IETDYQPAQQ EVVVDTASVG
SGTDVSGKID SGKETDLWKP VINELKTLGE TTSQEDMSWV YIFITGFVGG LLALFTPCVW
PIIPMTVSFF LKRSKDKKKG IRDAWTYGAS IVVIYVTLGL AITLIFGASA LNALSTNAVF
NILFCLMLIV FAASFFGAFE ITLPSKWSTA VDSKAEATGG LLSIFLMAFT LSLVSFSCTG
PIIGFLLVQV STTGSVVAPA IGMLGFAIAL ALPFTLFALF PSWLKSMPKS GGWMNVIKVT
LGFLELAFAL KFLSVADLAY GWRILDRETF LALWIVLFAL LGFYLLGKIK FPHDDDNTKV
SVPRFFMAMA SLAFAVYMVP GLWGAPLKAV SAFAPPMQTQ DFNLYNNEVH AKFDDYDLGM
EYARQHGKPV MLDFTGYGCV NCRKMELAVW TDSKVSDIIN NDYVLITLYV DNKTPLPSPV
KIMENGTERT LRTVGDKWSY LQRVKFGANA QPFYVLIDNE GKPLNKSYSY DEDIPKYIDF
LQTGLKNYKK EK
//
