ID E6SRA4_BACT6 Unreviewed; 597 AA.
AC E6SRA4;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Creatinase {ECO:0000313|EMBL:ADV43048.1};
GN OrderedLocusNames=Bache_1038 {ECO:0000313|EMBL:ADV43048.1};
OS Bacteroides helcogenes (strain ATCC 35417 / DSM 20613 / JCM 6297 / CCUG
OS 15421 / P 36-108).
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC Bacteroides.
OX NCBI_TaxID=693979 {ECO:0000313|EMBL:ADV43048.1, ECO:0000313|Proteomes:UP000008630};
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=P 36-108;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S.,
RA Kyrpides N., Mavromatis K., Ivanova N., Zeytun A., Brettin T., Detter J.C.,
RA Tapia R., Han C., Land M., Hauser L., Markowitz V., Cheng J.-F.,
RA Hugenholtz P., Woyke T., Wu D., Gronow S., Wellnitz S., Brambilla E.,
RA Klenk H.-P., Eisen J.A.;
RT "The complete genome of Bacteroides helcogenes P 36-108.";
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADV43048.1, ECO:0000313|Proteomes:UP000008630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35417 / DSM 20613 / JCM 6297 / CCUG 15421 / P 36-108
RC {ECO:0000313|Proteomes:UP000008630};
RX PubMed=21475586; DOI=10.4056/sigs.1513795;
RA Pati A., Gronow S., Zeytun A., Lapidus A., Nolan M., Hammon N.,
RA Deshpande S., Cheng J.F., Tapia R., Han C., Goodwin L., Pitluck S.,
RA Liolios K., Pagani I., Ivanova N., Mavromatis K., Chen A., Palaniappan K.,
RA Land M., Hauser L., Chang Y.J., Jeffries C.D., Detter J.C., Brambilla E.,
RA Rohde M., Goker M., Woyke T., Bristow J., Eisen J.A., Markowitz V.,
RA Hugenholtz P., Kyrpides N.C., Klenk H.P., Lucas S.;
RT "Complete genome sequence of Bacteroides helcogenes type strain (P 36-
RT 108).";
RL Stand. Genomic Sci. 4:45-53(2011).
CC -!- SIMILARITY: Belongs to the peptidase M24B family.
CC {ECO:0000256|ARBA:ARBA00008766}.
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DR EMBL; CP002352; ADV43048.1; -; Genomic_DNA.
DR RefSeq; WP_013546661.1; NC_014933.1.
DR AlphaFoldDB; E6SRA4; -.
DR STRING; 693979.Bache_1038; -.
DR KEGG; bhl:Bache_1038; -.
DR PATRIC; fig|693979.3.peg.1105; -.
DR eggNOG; COG0006; Bacteria.
DR HOGENOM; CLU_011781_2_4_10; -.
DR OrthoDB; 9806388at2; -.
DR Proteomes; UP000008630; Chromosome.
DR GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR CDD; cd01085; APP; 1.
DR Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 1.
DR Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 2.
DR InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR InterPro; IPR000587; Creatinase_N.
DR InterPro; IPR000994; Pept_M24.
DR InterPro; IPR033740; Pept_M24B.
DR InterPro; IPR032416; Peptidase_M24_C.
DR PANTHER; PTHR43763; XAA-PRO AMINOPEPTIDASE 1; 1.
DR PANTHER; PTHR43763:SF6; XAA-PRO AMINOPEPTIDASE 1; 1.
DR Pfam; PF01321; Creatinase_N; 1.
DR Pfam; PF16189; Creatinase_N_2; 1.
DR Pfam; PF00557; Peptidase_M24; 1.
DR Pfam; PF16188; Peptidase_M24_C; 1.
DR SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008630}.
FT DOMAIN 8..133
FT /note="Creatinase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01321"
FT DOMAIN 312..522
FT /note="Peptidase M24"
FT /evidence="ECO:0000259|Pfam:PF00557"
FT DOMAIN 533..592
FT /note="Peptidase M24 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF16188"
SQ SEQUENCE 597 AA; 66582 MW; 3B2F4AACC2D879EE CRC64;
MNRTISQRIN ALRALLKEKG IDAFIIPSTD PHLSEYVAPH WQSREWISGF TGSAGTVVVT
SKKAGLWTDS RYFLQAALQL EGSGIDLYKE MLPETPTISE FLKTNLASRM TVGIDGKVFS
TEEVIKLKSG LEKNGIIVKC ISDPMNSIWT ERPAMPEAPA FIYETKYAGR NSTEKLTDIR
KEMKRNGAEA LLVSALDEIA WTLNIRGTDV HCNPVTVSYL LLTEQEVHFF IQPLKVTNEL
AAYLKETGIE IHSYEDIESF LGNLSTDNIL LNPAKTNYAV YSAIRPNCRI IEGVSPIAFL
KAIRNQQEIA GIHTAMQRDG IALVKFLKWL ENAVPTGKET EISIDKKLHG FRAEQPLYMG
ESFDTIAGYK EHGAIVHYEA TPETDVPVLP KGFLLLDSGA QYMDGTTDIT RTIALGELTE
EEKEDYTLIL KGHIALATAV FPAGTRGAQL DVLARMPIWK HRMNFLHGTG HGVGHFLNVH
EGPQSIRMNE NPVTLQPGMV TSNEPGVYKT GSHGIRTENL VLTVPAGEGM FGNYLKFETI
TLCPICKKGI IKEMLTTEET EWLDQYHQKV YEKLSPGLNK EEQEWLKEAC KSLTSNH
//
