GenomeNet

Database: UniProt
Entry: E6TV65_BACCJ
LinkDB: E6TV65_BACCJ
Original site: E6TV65_BACCJ 
ID   E6TV65_BACCJ            Unreviewed;       298 AA.
AC   E6TV65;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   08-MAR-2011, sequence version 1.
DT   13-FEB-2019, entry version 45.
DE   RecName: Full=Prephenate dehydratase {ECO:0000256|RuleBase:RU361254};
DE            Short=PDT {ECO:0000256|RuleBase:RU361254};
DE            EC=4.2.1.51 {ECO:0000256|RuleBase:RU361254};
GN   Name=pheA {ECO:0000256|RuleBase:RU361254};
GN   OrderedLocusNames=Bcell_1486 {ECO:0000313|EMBL:ADU29749.1};
OS   Bacillus cellulosilyticus (strain ATCC 21833 / DSM 2522 / FERM P-1141
OS   / JCM 9156 / N-4).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=649639 {ECO:0000313|EMBL:ADU29749.1, ECO:0000313|Proteomes:UP000001401};
RN   [1] {ECO:0000313|EMBL:ADU29749.1, ECO:0000313|Proteomes:UP000001401}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 21833 / DSM 2522 / FERM P-1141 / JCM 9156 / N-4
RC   {ECO:0000313|Proteomes:UP000001401};
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA   Pitluck S., Chertkov O., Detter J.C., Han C., Tapia R., Land M.,
RA   Hauser L., Jeffries C., Kyrpides N., Ivanova N., Mikhailova N.,
RA   Brumm P., Mead D., Woyke T.;
RT   "Complete sequence of Bacillus cellulosilyticus DSM 2522.";
RL   Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+) + prephenate = 3-phenylpyruvate + CO2 + H2O;
CC         Xref=Rhea:RHEA:21648, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16526, ChEBI:CHEBI:18005, ChEBI:CHEBI:29934;
CC         EC=4.2.1.51; Evidence={ECO:0000256|RuleBase:RU361254};
CC   -!- PATHWAY: Amino-acid biosynthesis; L-phenylalanine biosynthesis;
CC       phenylpyruvate from prephenate: step 1/1.
CC       {ECO:0000256|RuleBase:RU361254}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP002394; ADU29749.1; -; Genomic_DNA.
DR   STRING; 649639.Bcell_1486; -.
DR   EnsemblBacteria; ADU29749; ADU29749; Bcell_1486.
DR   KEGG; bco:Bcell_1486; -.
DR   eggNOG; ENOG4105CQC; Bacteria.
DR   eggNOG; COG0077; LUCA.
DR   HOGENOM; HOG000018970; -.
DR   KO; K04518; -.
DR   OMA; REVMSAC; -.
DR   BioCyc; BCEL649639:G1GPN-1519-MONOMER; -.
DR   UniPathway; UPA00121; UER00345.
DR   Proteomes; UP000001401; Chromosome.
DR   GO; GO:0004106; F:chorismate mutase activity; IEA:InterPro.
DR   GO; GO:0004664; F:prephenate dehydratase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009094; P:L-phenylalanine biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR002912; ACT_dom.
DR   InterPro; IPR008242; Chor_mutase/pphenate_deHydtase.
DR   InterPro; IPR001086; Preph_deHydtase.
DR   InterPro; IPR018528; Preph_deHydtase_CS.
DR   Pfam; PF00800; PDT; 1.
DR   PIRSF; PIRSF001500; Chor_mut_pdt_Ppr; 1.
DR   PROSITE; PS51671; ACT; 1.
DR   PROSITE; PS00857; PREPHENATE_DEHYDR_1; 1.
DR   PROSITE; PS00858; PREPHENATE_DEHYDR_2; 1.
DR   PROSITE; PS51171; PREPHENATE_DEHYDR_3; 1.
PE   4: Predicted;
KW   Amino-acid biosynthesis {ECO:0000256|RuleBase:RU361254};
KW   Aromatic amino acid biosynthesis {ECO:0000256|RuleBase:RU361254};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001401};
KW   Lyase {ECO:0000256|RuleBase:RU361254, ECO:0000313|EMBL:ADU29749.1};
KW   Phenylalanine biosynthesis {ECO:0000256|RuleBase:RU361254};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001401}.
FT   DOMAIN        9    188       Prephenate dehydratase.
FT                                {ECO:0000259|PROSITE:PS51171}.
FT   DOMAIN      208    285       ACT. {ECO:0000259|PROSITE:PS51671}.
FT   SITE        181    181       Essential for prephenate dehydratase
FT                                activity. {ECO:0000256|PIRSR:PIRSR001500-
FT                                2}.
SQ   SEQUENCE   298 AA;  33319 MW;  51D56F9E094E6AC0 CRC64;
     MEGENNMKTV AYLGPKGSFT EVAAKALLPN ETHIPFRSIP DCMDAVNEDA VDRAIVPLEN
     AIEGSVNITL DYLIHHQRME MAAEVTAPIF QNLMTNKKHA DDWKEIDAVY SHPQAIAQCH
     QFLRNYIPNA EIRYTNSTAE AAKFVSESEE KIAALANETS ASEYGLAIVK SKVNDYKNNS
     TRFIALQKGS LNKSFEQMDG VSLYKTTIMV TLPLDYTGAL HQVLSAFAWR KINLSKIESR
     PMKTGLGNYF FIIDIDMKKD EVLIPGVQEE LKALGCKVEV LGSYPCFQWE ALCALQNK
//
DBGET integrated database retrieval system