ID E6UEK2_RUMA7 Unreviewed; 443 AA.
AC E6UEK2;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Mannose-1-phosphate guanylyltransferase {ECO:0000313|EMBL:ADU20957.1};
DE EC=2.7.7.13 {ECO:0000313|EMBL:ADU20957.1};
GN OrderedLocusNames=Rumal_0402 {ECO:0000313|EMBL:ADU20957.1};
OS Ruminococcus albus (strain ATCC 27210 / DSM 20455 / JCM 14654 / NCDO 2250 /
OS 7).
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Ruminococcus.
OX NCBI_TaxID=697329 {ECO:0000313|EMBL:ADU20957.1, ECO:0000313|Proteomes:UP000006919};
RN [1] {ECO:0000313|EMBL:ADU20957.1, ECO:0000313|Proteomes:UP000006919}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27210 / DSM 20455 / JCM 14654 / NCDO 2250 / 7
RC {ECO:0000313|Proteomes:UP000006919};
RX PubMed=21914885; DOI=10.1128/JB.05621-11;
RA Suen G., Stevenson D.M., Bruce D.C., Chertkov O., Copeland A., Cheng J.F.,
RA Detter C., Detter J.C., Goodwin L.A., Han C.S., Hauser L.J., Ivanova N.N.,
RA Kyrpides N.C., Land M.L., Lapidus A., Lucas S., Ovchinnikova G.,
RA Pitluck S., Tapia R., Woyke T., Boyum J., Mead D., Weimer P.J.;
RT "Complete genome of the cellulolytic ruminal bacterium Ruminococcus albus
RT 7.";
RL J. Bacteriol. 193:5574-5575(2011).
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DR EMBL; CP002403; ADU20957.1; -; Genomic_DNA.
DR RefSeq; WP_013497149.1; NZ_KK211249.1.
DR AlphaFoldDB; E6UEK2; -.
DR STRING; 697329.Rumal_0402; -.
DR KEGG; ral:Rumal_0402; -.
DR eggNOG; COG0836; Bacteria.
DR eggNOG; COG1917; Bacteria.
DR HOGENOM; CLU_035527_1_0_9; -.
DR OrthoDB; 9806359at2; -.
DR Proteomes; UP000006919; Chromosome.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0004475; F:mannose-1-phosphate guanylyltransferase (GTP) activity; IEA:UniProtKB-EC.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd02213; cupin_PMI_typeII_C; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR013096; Cupin_2.
DR InterPro; IPR005835; NTP_transferase_dom.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR InterPro; IPR011051; RmlC_Cupin_sf.
DR PANTHER; PTHR46390; MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE; 1.
DR PANTHER; PTHR46390:SF1; MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE; 1.
DR Pfam; PF07883; Cupin_2; 1.
DR Pfam; PF00483; NTP_transferase; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
DR SUPFAM; SSF51182; RmlC-like cupins; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleotidyltransferase {ECO:0000313|EMBL:ADU20957.1};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ADU20957.1}.
FT DOMAIN 3..268
FT /note="Nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF00483"
FT DOMAIN 362..414
FT /note="Cupin type-2"
FT /evidence="ECO:0000259|Pfam:PF07883"
SQ SEQUENCE 443 AA; 49454 MW; C460234630AAB6FA CRC64;
MKIILLSGGS GKRLWPLSND VQSKQFIRLF KNDDGCYESM LQRVYRQISS VSGAGITIAT
SRSQVSAIKN QLNDKVSICI EPCRRDTFPA IALAAEFLHD VKDTDRDECV IVCPVDPYVD
DSYYECVRSL EAHVQKGDTA LTLMGIEPTY PSDKYGYIIP DEKAEVSLVK SFKEKPDKKT
AEEYLKKGAL WNAGVFAFKL GYLIDKVHEI TGYTGYNELL ENYEKLEKIS FDYAVVEKES
SIKAVRYSGD WKDVGTWNMM AEVMADATKG DVTLDDTCEN TQVVNELSIP VLCMGCRDMV
IAVSGDGILV SDKERSGYMK PYVEKIAGEA HFAEKSWGTY TVMDSEAEAL TVKIKLYAGN
NMNYHSHKNR SEVWTVLSGE GRFIIDGIER VVGPGDTVSA KAGVKHMIIA DTDMSIIEVQ
TGKDIDRKDK TVYECEYGKG NKE
//
