ID E6UKV6_RUMA7 Unreviewed; 2936 AA.
AC E6UKV6;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=N-6 DNA methylase {ECO:0000313|EMBL:ADU24302.1};
GN OrderedLocusNames=Rumal_3878 {ECO:0000313|EMBL:ADU24302.1};
OS Ruminococcus albus (strain ATCC 27210 / DSM 20455 / JCM 14654 / NCDO 2250 /
OS 7).
OG Plasmid pRUMAL02 {ECO:0000313|EMBL:ADU24302.1,
OG ECO:0000313|Proteomes:UP000006919}.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Ruminococcus.
OX NCBI_TaxID=697329 {ECO:0000313|EMBL:ADU24302.1, ECO:0000313|Proteomes:UP000006919};
RN [1] {ECO:0000313|Proteomes:UP000006919}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27210 / DSM 20455 / JCM 14654 / NCDO 2250 / 7
RC {ECO:0000313|Proteomes:UP000006919};
RC PLASMID=pRUMAL02 {ECO:0000313|Proteomes:UP000006919};
RX PubMed=21914885; DOI=10.1128/JB.05621-11;
RA Suen G., Stevenson D.M., Bruce D.C., Chertkov O., Copeland A., Cheng J.F.,
RA Detter C., Detter J.C., Goodwin L.A., Han C.S., Hauser L.J., Ivanova N.N.,
RA Kyrpides N.C., Land M.L., Lapidus A., Lucas S., Ovchinnikova G.,
RA Pitluck S., Tapia R., Woyke T., Boyum J., Mead D., Weimer P.J.;
RT "Complete genome of the cellulolytic ruminal bacterium Ruminococcus albus
RT 7.";
RL J. Bacteriol. 193:5574-5575(2011).
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DR EMBL; CP002405; ADU24302.1; -; Genomic_DNA.
DR RefSeq; WP_013483842.1; NZ_KK211249.1.
DR KEGG; ral:Rumal_3878; -.
DR HOGENOM; CLU_000181_0_1_9; -.
DR OrthoDB; 9815272at2; -.
DR Proteomes; UP000006919; Plasmid pRUMAL02.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR41313; ADENINE-SPECIFIC METHYLTRANSFERASE; 1.
DR PANTHER; PTHR41313:SF1; DNA METHYLASE ADENINE-SPECIFIC DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR PRINTS; PR00507; N12N6MTFRASE.
DR SMART; SM00487; DEXDc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Methyltransferase {ECO:0000313|EMBL:ADU24302.1};
KW Plasmid {ECO:0000313|EMBL:ADU24302.1};
KW Transferase {ECO:0000313|EMBL:ADU24302.1}.
FT DOMAIN 2481..2667
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 237..356
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 661..720
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2915..2936
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 2204..2252
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2825..2867
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 237..253
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 300..330
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 661..681
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 682..696
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 706..720
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2919..2936
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2936 AA; 333440 MW; D7B8F624C4388842 CRC64;
MNNRYQSVCY NWSEVTERLR RDKQTLARFL RFSASLYKMG FPDAALVFYH DPNATKVAEL
ETWNKLGRFV NRGAHSIAVF GEGDRCRHLF DISQTNGKPV PNGWQLTEDV AGELVDVISE
KYGRECRDIH EALAAVAVDN IKAHNSEMQY TISQIDMPQE AVADYQRSVV SAVRFVIANR
CEQNGGMPLS GNINLNAADY FKDTRDVIRF CDLVQRSAKD SLLEIEREVI QILRRRREKE
HELQTKPDRT DVSRGSIQRQ SAGDRTAENP DRQVGQNVAG LGAHGVPDRG DGADSNGQVE
HNSEGDRQTG REPLQRAGRT LPKREPSPRD IQRNAGVGEN KTSDDRTPDN GGDSVSAEKL
TADALIQRYL QSDFNRRPDS YEIAGRFLAD FLDTDVNIVE FFRKHEAYKY SERQQAEIIL
LIENALRMRE QEQVKTEQPP EVTVAEPATS PYAGIEIPTN MEPVFPTEIV EDITPPEEVP
EVDLSEPTEE EVESIIDNQP QDDTVIVKNE AVITTELPPI TDENIIFGIL RNDQFFAIKR
DQIAAFFENN TDHDERVAFV KQIFNSDYSE LLLGDNEDTR YGYKTYDEGI HIWKGSFLTR
TMESGFSWDL VQSFYADMVE RGLLINTAVS EIDEPIFAEP TEEKKYPEPE EDIDDFEELT
EEFEAEDETE EEISDEDIDT PAPVNDFDRD DNEGAEQLSF FGEPEPVKTA KKKSQEKEPK
KLLNVDTSIR AISNDMIYYV LRCGSPERGS LSRIVAQFQK GKTDEENSEF LRKEFGNDGR
GYIYNTPDFS KTAHISSWFD DFGIKITLGD NVDENGIPNS KIPWLIAARR INDLLENGEF
CSQDIIDGAA EKEIKDIADR LWYLHQDIDY DNYEYFIPKD MFKGGFPEST ERIKIALLDK
DTLQSYIDGL TQLVNDYEQN RDILRFHFHK PKELLYRLKD LQIERRQFVT KPDFAFKGHY
FISEREKDAL LGLGSGYSDG KFRIQKYFKE SHTLPEQIKF LKNEYGTGGG SRRGGDEWHD
SKGIAYVRGE KIGTPDAKTL MKWNEVVERI SRLVSEGKYI TQKDIDSKIH DCKRIVQDYD
PDSYDSFEKE YERRRYHEAL QFLGEQGIVA EGVTAVEQKP VEKLIQRAQD MGIPVEITGQ
AAEQEQAVYM DIRDESFIEL HQTDEGISYS VYAPDLTLTD GGVWEMEESM SLLTAAAEIL
ATTSNALAEV EDYNHFMALV DMDVSLDIPR ELAQLKADIF ANLPNEAAEV IDVDYTEVDE
APVAERAEET PTETEPKKVA VNAPERITAV PVVPKSGTPI TYHFNEGDIV QGGAKSKFKA
NIEAIKTLQK IEAENRYATP EEQSILAGYV GWGGIPQAFV TDLAADSIGG NLGDAAPTGW
EEEQQELRSL LSDDEYKAAR ESTLTSFYTP PEVTDGVFQA LRQLGFEGGN ILEPSMGVGN
FFAKMPDDIR DSSKLYGVEL DSISGRIAQL LNPEDRIQIT GFEKTRFNNN SFDVVIGNVP
FGDYRVSDKA YDKLGLKIHD YFAVKSIDKV KPGGVVAIVT SKFTMDKIND KARRHLAERC
DLLGAVRLPN NAFKKNAGTE TTTDILFFQK RETLTVEIPS WVHFGQTADG IPCNQYFVDN
PDMVLGTMAW DERMKGKYGD DSRVTTCIPD DSKPLSEQLQ AAISKIKGKI ETVKIVEEGK
KDIEIIPADP TVRNYTHTVV NGKLFFRENE IMIAVQETGK TLDRMMGMHQ IRQKAMAVID
AQARGCDDAE LKKLQAELNY TYDRFKRAYG AITDRANERV FQHDDDYNTL AALEIVDTEK
KTVEKAEIFS KRTIMPEVEI VSCETPQEAL QISIDRKGKV DIAFMAELVG VEPDEIISEL
GTDIYRNPQK VKDNDPLSGY EDASEYLSGN VREKLRIAEE YSKHIDSSFE RNVEALKAVV
PKDLEASEIS VRIGANWVDV EDYNRFMREV LKGDIYSHPI TRTRMGEYKI DGRYQDRSVA
ATQTYGTSRM SSYHILENLL NQRDIVVRDK REEDGRVWYE INAKETQLAK DKARVIKEAF
RTWLWENMDR REKYVERYNN LFNAIRGREY DGSHQTYPGK NPAIQMRPHQ NNAIMRGKLG
GNTLLAHCVG AGKSFEMVAI TMEKKRLGLI SKACVVVPKH LTLQMASEWI RLYPNAKLLV
ARPEDFTKEN RQRFIARCVT GDYDAVIMSF NQFERIPMST EYRQQFMERE LDELMAALEE
VDSSDRISVK ALERQKKKLE EHLEKLMSSK KDNSLCFEKL GFDYLVCDEA HYYKNCFVAT
KMSNVAGVQT TAAQKSEDML MKTQYLNDKY GCNNILYATG TPCTNSMVEF YVMQRYLRPD
LLEKAGLETF DDWASTFGEV VSQLEIKPAG NGFQMKNRFS KFVNIPELML MYKEFADIQT
PDMIKLPVPD LKTGKPIVIS AKPDEYQKEY MEQLAQRAEM IHCGGVDPRE DNMLRITHEA
RLLGLDCRCM NPEAVPAPDS KVNKLLDILV ENYNNTMAER GVQIVFCDIA INEDAEHFSI
YEAIKDDLVK RGIPRDEICF AGDAKNDKAR AEMFEQLRQG EKRFILASTS KLGTGANIQD
RICAIHHLDI PWKPADLTQQ DGRGVRQGNM FKEVGIYHYL TENTFDAYMM GIITNKAKFI
NQIMTSKDPV RVSEDVDEMV LTYSEMQAIA SGNPMIKEKI QLDNDVATLK MLEAEYKKSL
YRYQEQAERT LPQRIEQYST YLEKASADIA QFSVNHPDGT AFQIEIDGKV YSEATSEHVR
DEAGEALEKA IIKVSTTGES MRVGSYFGFD LLLEKNPQNL TFFDQGAPCV ISLCGSLKYT
CDVNLENKQG NMRRIENLAA NEIAKRIVQY KNDIEKAKAN LAEAKENLTK PFDRADELAE
KLARLDVVNE ALSSGKGDDA IPSVVEEVAD MPNYKPKVTV LNPPTNVSTP TKSNRR
//
