ID E6UX05_VARPE Unreviewed; 583 AA.
AC E6UX05;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Sulfatase {ECO:0000313|EMBL:ADU36550.1};
GN OrderedLocusNames=Varpa_2348 {ECO:0000313|EMBL:ADU36550.1};
OS Variovorax paradoxus (strain EPS).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Variovorax.
OX NCBI_TaxID=595537 {ECO:0000313|EMBL:ADU36550.1, ECO:0000313|Proteomes:UP000008917};
RN [1] {ECO:0000313|Proteomes:UP000008917}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EPS {ECO:0000313|Proteomes:UP000008917};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N.,
RA Ivanova N., Ovchinnikova G., Orwin P., Han J.-I.G., Woyke T.;
RT "Complete sequence of Variovorax paradoxus EPS.";
RL Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADU36550.1, ECO:0000313|Proteomes:UP000008917}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EPS {ECO:0000313|EMBL:ADU36550.1,
RC ECO:0000313|Proteomes:UP000008917};
RX PubMed=24158554;
RA Han J.I., Spain J.C., Leadbetter J.R., Ovchinnikova G., Goodwin L.A.,
RA Han C.S., Woyke T., Davenport K.W., Orwin P.M.;
RT "Genome of the Root-Associated Plant Growth-Promoting Bacterium Variovorax
RT paradoxus Strain EPS.";
RL Genome Announc. 1:e00843-e00813(2013).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP002417; ADU36550.1; -; Genomic_DNA.
DR RefSeq; WP_013540784.1; NC_014931.1.
DR AlphaFoldDB; E6UX05; -.
DR STRING; 595537.Varpa_2348; -.
DR KEGG; vpe:Varpa_2348; -.
DR eggNOG; COG2194; Bacteria.
DR HOGENOM; CLU_018534_1_0_4; -.
DR OrthoDB; 9786870at2; -.
DR Proteomes; UP000008917; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016772; F:transferase activity, transferring phosphorus-containing groups; IEA:InterPro.
DR CDD; cd16017; LptA; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR012549; EptA-like_N.
DR InterPro; IPR040423; PEA_transferase.
DR InterPro; IPR000917; Sulfatase_N.
DR PANTHER; PTHR30443; INNER MEMBRANE PROTEIN; 1.
DR PANTHER; PTHR30443:SF0; PHOSPHOETHANOLAMINE TRANSFERASE EPTA; 1.
DR Pfam; PF08019; EptA_B_N; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 43..64
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 76..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 108..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 150..171
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 183..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 92..235
FT /note="Phosphoethanolamine transferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08019"
FT DOMAIN 266..564
FT /note="Sulfatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00884"
SQ SEQUENCE 583 AA; 64384 MW; 90BC9262A0967A5B CRC64;
MSFSRIEPAP VHSAPLFEAS AQQLSSPGAL WQRVDQWLTR PRSAALVMLW LGLYLVLTTN
WPLWNELARI GGAPSTYLPT VIAMSLLTLC GTVAMLSLTA WSRWLKPLWF LVVVLAAVTQ
HYMLEYRVVM DPTMIANALQ TDPNEARDLL SWRMAFNVLV VALPAGLMLW RMRIAPMGFL
SKLWRNAALL VLAVVVALAT GVAMNRQLAP LMRNNIHLRY MMNPIASLYS TGAVFIKPLF
KRSGKLIPIT AGTTLGASYA AQVRPPMFVV VVGETARADH FALNGYARDT TPELAKRNVL
SYRDVHSCGT NTLASVPCMF SPLGKQGYES RKDDYENLVD VLQASGLAVL WLDNQAGCKD
VCTRIPNASA FDGLDAATKK ALCDGDECLD EVMLKNLDAR IAALPAERRA KGVVLVMHQM
GSHGPAYYKR SAPDVKRFTP ECKTNALAEC GHNELMNVYD NSIVQTDRFL ADTIDWLKAQ
SKQYDPAMLY VSDHGESLGE YGLFLHGVPY SFAPEAQKHV PMVTWFSDGM SERRKLSRSC
MEAGLDAPLT HDNLYHTVLG LLDVNTPTYK PALDALASCR AKA
//
