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Database: UniProt
Entry: E6V4B5_VARPE
LinkDB: E6V4B5_VARPE
Original site: E6V4B5_VARPE 
ID   E6V4B5_VARPE            Unreviewed;       492 AA.
AC   E6V4B5;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   08-MAR-2011, sequence version 1.
DT   05-JUN-2019, entry version 52.
DE   RecName: Full=Glycogen synthase {ECO:0000256|HAMAP-Rule:MF_00484};
DE            EC=2.4.1.21 {ECO:0000256|HAMAP-Rule:MF_00484};
DE   AltName: Full=Starch [bacterial glycogen] synthase {ECO:0000256|HAMAP-Rule:MF_00484};
GN   Name=glgA {ECO:0000256|HAMAP-Rule:MF_00484};
GN   OrderedLocusNames=Varpa_0439 {ECO:0000313|EMBL:ADU34661.1};
OS   Variovorax paradoxus (strain EPS).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Variovorax.
OX   NCBI_TaxID=595537 {ECO:0000313|EMBL:ADU34661.1, ECO:0000313|Proteomes:UP000008917};
RN   [1] {ECO:0000313|Proteomes:UP000008917}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EPS {ECO:0000313|Proteomes:UP000008917};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L.,
RA   Pitluck S., Teshima H., Detter J.C., Han C., Tapia R., Land M.,
RA   Hauser L., Kyrpides N., Ivanova N., Ovchinnikova G., Orwin P.,
RA   Han J.-I.G., Woyke T.;
RT   "Complete sequence of Variovorax paradoxus EPS.";
RL   Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ADU34661.1, ECO:0000313|Proteomes:UP000008917}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EPS {ECO:0000313|EMBL:ADU34661.1,
RC   ECO:0000313|Proteomes:UP000008917};
RX   PubMed=24158554;
RA   Han J.I., Spain J.C., Leadbetter J.R., Ovchinnikova G., Goodwin L.A.,
RA   Han C.S., Woyke T., Davenport K.W., Orwin P.M.;
RT   "Genome of the Root-Associated Plant Growth-Promoting Bacterium
RT   Variovorax paradoxus Strain EPS.";
RL   Genome Announc. 1:e00843-13(2013).
CC   -!- FUNCTION: Synthesizes alpha-1,4-glucan chains using ADP-glucose.
CC       {ECO:0000256|HAMAP-Rule:MF_00484}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=[(1->4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose =
CC         [(1->4)-alpha-D-glucosyl](n+1) + ADP + H(+);
CC         Xref=Rhea:RHEA:18189, Rhea:RHEA-COMP:9584, Rhea:RHEA-COMP:9587,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:15444, ChEBI:CHEBI:57498,
CC         ChEBI:CHEBI:456216; EC=2.4.1.21; Evidence={ECO:0000256|HAMAP-
CC         Rule:MF_00484};
CC   -!- PATHWAY: Glycan biosynthesis; glycogen biosynthesis.
CC       {ECO:0000256|HAMAP-Rule:MF_00484}.
CC   -!- SIMILARITY: Belongs to the glycosyltransferase 1 family.
CC       Bacterial/plant glycogen synthase subfamily. {ECO:0000256|HAMAP-
CC       Rule:MF_00484, ECO:0000256|SAAS:SAAS00554699}.
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DR   EMBL; CP002417; ADU34661.1; -; Genomic_DNA.
DR   RefSeq; WP_013538907.1; NC_014931.1.
DR   STRING; 595537.Varpa_0439; -.
DR   EnsemblBacteria; ADU34661; ADU34661; Varpa_0439.
DR   GeneID; 29717405; -.
DR   KEGG; vpe:Varpa_0439; -.
DR   eggNOG; ENOG4105CXW; Bacteria.
DR   eggNOG; COG0297; LUCA.
DR   HOGENOM; HOG000294941; -.
DR   KO; K00703; -.
DR   OMA; CAPVIKA; -.
DR   OrthoDB; 83240at2; -.
DR   BioCyc; VPAR595537:G1GQO-441-MONOMER; -.
DR   UniPathway; UPA00164; -.
DR   Proteomes; UP000008917; Chromosome.
DR   GO; GO:0033201; F:alpha-1,4-glucan synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004373; F:glycogen (starch) synthase activity; IEA:InterPro.
DR   GO; GO:0009011; F:starch synthase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00484; Glycogen_synth; 1.
DR   InterPro; IPR001296; Glyco_trans_1.
DR   InterPro; IPR011835; GS/SS.
DR   InterPro; IPR013534; Starch_synth_cat_dom.
DR   Pfam; PF08323; Glyco_transf_5; 1.
DR   Pfam; PF00534; Glycos_transf_1; 1.
DR   TIGRFAMs; TIGR02095; glgA; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000008917};
KW   Glycogen biosynthesis {ECO:0000256|HAMAP-Rule:MF_00484};
KW   Glycosyltransferase {ECO:0000256|HAMAP-Rule:MF_00484,
KW   ECO:0000256|SAAS:SAAS00554704, ECO:0000313|EMBL:ADU34661.1};
KW   Transferase {ECO:0000256|HAMAP-Rule:MF_00484,
KW   ECO:0000256|SAAS:SAAS00554689, ECO:0000313|EMBL:ADU34661.1}.
FT   DOMAIN        2    245       Glyco_transf_5. {ECO:0000259|Pfam:
FT                                PF08323}.
FT   DOMAIN      301    460       Glycos_transf_1. {ECO:0000259|Pfam:
FT                                PF00534}.
FT   BINDING      15     15       ADP-glucose. {ECO:0000256|HAMAP-Rule:
FT                                MF_00484}.
SQ   SEQUENCE   492 AA;  52881 MW;  175B26533ACE25FB CRC64;
     MRILQVSAEL FPLLKTGGLA DVAGALPLAL MAAGQDARVL LPGFPAIVAG VRDLAPVAEL
     TAPWGSERFA LRAGHIAIDG APPIPAYVID APALYDRPGN PYEDATRQPY GDNHRRFALL
     GWAAAQLAQG LDPAWRPEVV HAHDWHAGLA PAYLHFAREA GSTRAGSVFT VHNLAYQGIS
     APWNFADLGL PAPAFHMNGL EYHGQVSFMK AGLYFADRIT TVSPTYAREI QTPEQGCGLD
     GLLRQRSGAL TGILNAVDDK VWNPAADAAL VQGYHSPEGR HMAGKARCKA VLQHQLGLAE
     RPDAPLFILV SRLTEQKGLH LVLGGIDALL AQGGQLALLG SGEAWLEEAF RQRAAAAPQS
     VSVTIGYNET LAHQLFGGGD VTLVPSLFEP CGLTQMYGLK YGSLPLVRRV GGLADTVVDS
     TLEDMASGEA TGFVFDRFDA ADYERALRRA FALYERAPDW RRVRGNAMRR PADWATAAAQ
     YIDVYRQAQA PT
//
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