ID E6V7C6_VARPE Unreviewed; 306 AA.
AC E6V7C6;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Pyruvate carboxyltransferase {ECO:0000313|EMBL:ADU39495.1};
GN OrderedLocusNames=Varpa_5339 {ECO:0000313|EMBL:ADU39495.1};
OS Variovorax paradoxus (strain EPS).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Variovorax.
OX NCBI_TaxID=595537 {ECO:0000313|EMBL:ADU39495.1, ECO:0000313|Proteomes:UP000008917};
RN [1] {ECO:0000313|Proteomes:UP000008917}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EPS {ECO:0000313|Proteomes:UP000008917};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N.,
RA Ivanova N., Ovchinnikova G., Orwin P., Han J.-I.G., Woyke T.;
RT "Complete sequence of Variovorax paradoxus EPS.";
RL Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADU39495.1, ECO:0000313|Proteomes:UP000008917}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EPS {ECO:0000313|EMBL:ADU39495.1,
RC ECO:0000313|Proteomes:UP000008917};
RX PubMed=24158554;
RA Han J.I., Spain J.C., Leadbetter J.R., Ovchinnikova G., Goodwin L.A.,
RA Han C.S., Woyke T., Davenport K.W., Orwin P.M.;
RT "Genome of the Root-Associated Plant Growth-Promoting Bacterium Variovorax
RT paradoxus Strain EPS.";
RL Genome Announc. 1:e00843-e00813(2013).
CC -!- SIMILARITY: Belongs to the HMG-CoA lyase family.
CC {ECO:0000256|ARBA:ARBA00009405}.
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DR EMBL; CP002417; ADU39495.1; -; Genomic_DNA.
DR RefSeq; WP_013543697.1; NC_014931.1.
DR AlphaFoldDB; E6V7C6; -.
DR STRING; 595537.Varpa_5339; -.
DR KEGG; vpe:Varpa_5339; -.
DR eggNOG; COG0119; Bacteria.
DR HOGENOM; CLU_022138_3_2_4; -.
DR OrthoDB; 9784013at2; -.
DR Proteomes; UP000008917; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016833; F:oxo-acid-lyase activity; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR CDD; cd07938; DRE_TIM_HMGL; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR043594; HMGL.
DR InterPro; IPR000891; PYR_CT.
DR PANTHER; PTHR42738; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR PANTHER; PTHR42738:SF7; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR Pfam; PF00682; HMGL-like; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
DR PROSITE; PS50991; PYR_CT; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Pyruvate {ECO:0000313|EMBL:ADU39495.1};
KW Transferase {ECO:0000313|EMBL:ADU39495.1}.
FT DOMAIN 7..278
FT /note="Pyruvate carboxyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS50991"
SQ SEQUENCE 306 AA; 32594 MW; 5D9BFFFD7110EBD3 CRC64;
MKLPTRVKLV DVGPRDGLQN EKQPVSAEVK IGLVHRLQDA GLNEIEVTSF VSPKWVPQMA
DNAEVMHGIQ RKPGVLYSVL TPNMKGFEAA IAAPREEWPD EIVVFGAASE AFSQKNINCS
IAESIERFAP VVAAALEKGI RVRGAMSCTV GCPYEGEIAP AKVGYLAQLM KGIGVQRVDV
ADTIGVGTPR KVQAAMEATL AHFEVDAISG HFHDTYGQAL VNTLAALEMG VWNFQSSSAG
LGGCPYAKGA TGNVATEDVV YMLRGMGIET GIDLDKLIDA GVYISEALGR EPNSRASKAI
RTKRAG
//
