ID E6VAU2_VARPE Unreviewed; 595 AA.
AC E6VAU2;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=PhoH family protein {ECO:0000313|EMBL:ADU36296.1};
GN OrderedLocusNames=Varpa_2089 {ECO:0000313|EMBL:ADU36296.1};
OS Variovorax paradoxus (strain EPS).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Variovorax.
OX NCBI_TaxID=595537 {ECO:0000313|EMBL:ADU36296.1, ECO:0000313|Proteomes:UP000008917};
RN [1] {ECO:0000313|Proteomes:UP000008917}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EPS {ECO:0000313|Proteomes:UP000008917};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N.,
RA Ivanova N., Ovchinnikova G., Orwin P., Han J.-I.G., Woyke T.;
RT "Complete sequence of Variovorax paradoxus EPS.";
RL Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADU36296.1, ECO:0000313|Proteomes:UP000008917}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EPS {ECO:0000313|EMBL:ADU36296.1,
RC ECO:0000313|Proteomes:UP000008917};
RX PubMed=24158554;
RA Han J.I., Spain J.C., Leadbetter J.R., Ovchinnikova G., Goodwin L.A.,
RA Han C.S., Woyke T., Davenport K.W., Orwin P.M.;
RT "Genome of the Root-Associated Plant Growth-Promoting Bacterium Variovorax
RT paradoxus Strain EPS.";
RL Genome Announc. 1:e00843-e00813(2013).
CC -!- SIMILARITY: Belongs to the PhoH family.
CC {ECO:0000256|ARBA:ARBA00010393}.
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DR EMBL; CP002417; ADU36296.1; -; Genomic_DNA.
DR RefSeq; WP_013540532.1; NC_014931.1.
DR AlphaFoldDB; E6VAU2; -.
DR STRING; 595537.Varpa_2089; -.
DR KEGG; vpe:Varpa_2089; -.
DR eggNOG; COG1875; Bacteria.
DR HOGENOM; CLU_022283_0_0_4; -.
DR OrthoDB; 9766527at2; -.
DR Proteomes; UP000008917; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR CDD; cd09883; PIN_VapC_PhoHL-ATPase; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003714; PhoH.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR InterPro; IPR002716; PIN_dom.
DR PANTHER; PTHR30473:SF2; PIN DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR30473; PROTEIN PHOH; 1.
DR Pfam; PF02562; PhoH; 1.
DR Pfam; PF13638; PIN_4; 1.
DR SMART; SM00670; PINc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
PE 3: Inferred from homology;
FT DOMAIN 129..271
FT /note="PIN"
FT /evidence="ECO:0000259|SMART:SM00670"
FT REGION 1..125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 24..38
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 595 AA; 64581 MW; 4D43076D58AD9392 CRC64;
MPLPPAPTKR AALLSPDAID APARSSHRGS RRSGDQRADE TTSNGPQPLE LFDNLSSEAA
GGGEAARPSR RAKSRPAPAS APAPQQPAAI QVETRVPTAP APTYAPAPAA AAPQAPARPK
RSKSTGPAKL FVLDTNVLLH DPMCLFRFEE HDIFLPMIVL EELDGHKKGT TEVARNGRQT
SRTLDALAGA QDADIDKGLK LDTTGHREAG GRLFFQTAPL DYSLPISLPQ GKADNQILGV
VHALRDEYAK DRPGKPKQEV VLVSKDINMR VKARALGLAA DDYQNDKTLE DGDLLYAGSL
ALPPDFWTRQ SKTVESWQSG SNTFYRISGP IVPNLYINQF VFFEAPGEPS MYARVTEIRD
KTAVLKTLKD YSSGKNAVWG VNTRNREQNF AMNLLMDPEI DFVTLTGTAG TGKTLMALAS
GLTQVLDDRR YTEIIMTRAT VSVGEDIGFL PGTEEEKMGP WMGALDDNLE FLAKGDGGGA
GEWGRAATNE LIRSRIKVKS MNFMRGRTFL NKYVIIDEAQ NLTPKQMKTL ITRAGPGTKI
ICMGNLAQID TPYLTEGSSG LTFAVDKFKG WPHGGHITLA RGERSRLADF ASDVL
//
