ID E6VQM2_PSEA9 Unreviewed; 857 AA.
AC E6VQM2;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE SubName: Full=Diguanylate cyclase {ECO:0000313|EMBL:ADU61749.1};
GN OrderedLocusNames=Daes_0732 {ECO:0000313|EMBL:ADU61749.1};
OS Pseudodesulfovibrio aespoeensis (strain ATCC 700646 / DSM 10631 / Aspo-2)
OS (Desulfovibrio aespoeensis).
OC Bacteria; Thermodesulfobacteriota; Desulfovibrionia; Desulfovibrionales;
OC Desulfovibrionaceae.
OX NCBI_TaxID=643562 {ECO:0000313|EMBL:ADU61749.1, ECO:0000313|Proteomes:UP000002191};
RN [1] {ECO:0000313|Proteomes:UP000002191}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700646 / DSM 10631 / Aspo-2
RC {ECO:0000313|Proteomes:UP000002191};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Chertkov O., Misra M., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Ovchinnikova G., Pedersen K., Jagevall S.,
RA Hazen T., Woyke T.;
RT "Complete sequence of Desulfovibrio aespoeensis Aspo-2.";
RL Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADU61749.1, ECO:0000313|Proteomes:UP000002191}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700646 / DSM 10631 / Aspo-2
RC {ECO:0000313|Proteomes:UP000002191};
RX PubMed=24874683;
RA Pedersen K., Bengtsson A., Edlund J., Rabe L., Hazen T., Chakraborty R.,
RA Goodwin L., Shapiro N.;
RT "Complete Genome Sequence of the Subsurface, Mesophilic Sulfate-Reducing
RT Bacterium Desulfovibrio aespoeensis Aspo-2.";
RL Genome Announc. 2:e00509-14(2014).
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DR EMBL; CP002431; ADU61749.1; -; Genomic_DNA.
DR RefSeq; WP_013513680.1; NC_014844.1.
DR AlphaFoldDB; E6VQM2; -.
DR STRING; 643562.Daes_0732; -.
DR KEGG; das:Daes_0732; -.
DR eggNOG; COG5001; Bacteria.
DR HOGENOM; CLU_000445_70_46_7; -.
DR OrthoDB; 7673416at2; -.
DR Proteomes; UP000002191; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004673; F:protein histidine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR033463; sCache_3.
DR InterPro; IPR029151; Sensor-like_sf.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF17203; sCache_3_2; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 170..190
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 188..240
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 295..336
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 370..422
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 454..587
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 596..854
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
FT COILED 239..270
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 857 AA; 95567 MW; CD69DA590D015056 CRC64;
MKAPKLFLKP LLFMVVIFGL ISLVTSVTFG NRLKREMTRE HESKALALAD SVAESDIVTI
LSQDAGGVQA RIDRYQRIAG VSYVLVADER GEIMAHTFVP DVPKVVRALV AGTAQLPGDE
VVLRDIVYGD NRYLHVSRPI LAGLAGSVHI GMDSEIIARH IREAVLEQQL VTLVLFGASL
LVAFVFILNI SKPLNLLAEY AGRVAAKDFD SVPEINSRDE VGQLARAMRS MARHIAELVG
NLEDRVRSKT QELQEARDAL RQKVDERTSE LLRANTQLKI EIAERKVIGD ALRKAEKKYR
TIFENALEGI YQTSPSGRFL SANPSLARIL GFKSADEMMG SVYDIGTQMY LEPGRRKEFL
RLIEETGEVK NFVSKVRRRD GRIIWISENA RRITDADGSV MCYEGSVEDI TLRKKAEDQL
KRQAFHDPLT GLPNRALFLD HLRMAMERGR RRRHLFAVIY MDLDRFKVIN DSLGHETGDE
LLRSVARVLE KCGRSVDTIA RFGGDEFAIL IEEISASRDA IAIARRILDG VRQPFTINGN
EVFTSASLGI VLKTDGYDRP EALLRDADTA MYRAKEHGKS RFKVFNQKMH DQALRLMALE
TDLRRAVDLR EFEVAYQPIV CLDTRRVCGF EALVRWRHPE HGVILPGDFI SLAEDTGLIY
AIDNFVLVAA CAQVKLWQTT FGHLMGELLT LNINISGKHF GQPMLLSQVT RALDDSGLNP
QALNIEITES ALMDNPAVAE EVLKQLKSLG AKVCIDDFGT GYSSLSYLQR FPIDVVKVDR
SFIDGVEGNL DSQAIVRTVF SLGESLGLKI VAEGVETPAQ LAFLENEGCR YVQGFLFYRP
LSATEVDELL AGGSIGS
//
