ID E6W1K2_DESIS Unreviewed; 792 AA.
AC E6W1K2;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Metal dependent phosphohydrolase {ECO:0000313|EMBL:ADU66551.1};
GN OrderedLocusNames=Selin_1824 {ECO:0000313|EMBL:ADU66551.1};
OS Desulfurispirillum indicum (strain ATCC BAA-1389 / DSM 22839 / S5).
OC Bacteria; Chrysiogenota; Chrysiogenetes; Chrysiogenales; Chrysiogenaceae;
OC Desulfurispirillum.
OX NCBI_TaxID=653733 {ECO:0000313|EMBL:ADU66551.1, ECO:0000313|Proteomes:UP000002572};
RN [1] {ECO:0000313|EMBL:ADU66551.1, ECO:0000313|Proteomes:UP000002572}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1389 / DSM 22839 / S5
RC {ECO:0000313|Proteomes:UP000002572};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Chertkov O., Held B., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Mikhailova N., Haggblom M., Rauschenbach I.,
RA Bini E., Woyke T.;
RT "Complete sequence of Desulfurispirillum indicum S5.";
RL Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP002432; ADU66551.1; -; Genomic_DNA.
DR RefSeq; WP_013506431.1; NC_014836.1.
DR AlphaFoldDB; E6W1K2; -.
DR STRING; 653733.Selin_1824; -.
DR KEGG; din:Selin_1824; -.
DR eggNOG; COG1480; Bacteria.
DR HOGENOM; CLU_015767_1_2_0; -.
DR InParanoid; E6W1K2; -.
DR OrthoDB; 9806952at2; -.
DR Proteomes; UP000002572; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd00077; HDc; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR011624; Metal-dep_PHydrolase_7TM_extra.
DR InterPro; IPR011621; Metal-dep_PHydrolase_7TM_intra.
DR NCBIfam; TIGR00277; HDIG; 1.
DR PANTHER; PTHR36442; CYCLIC-DI-AMP PHOSPHODIESTERASE PGPH; 1.
DR PANTHER; PTHR36442:SF1; CYCLIC-DI-AMP PHOSPHODIESTERASE PGPH; 1.
DR Pfam; PF07698; 7TM-7TMR_HD; 1.
DR Pfam; PF07697; 7TMR-HDED; 1.
DR Pfam; PF01966; HD; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS51831; HD; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:ADU66551.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002572};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 288..305
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 325..347
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 384..409
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 429..448
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 455..482
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 515..656
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
FT REGION 720..792
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 720..739
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 792 AA; 88588 MW; C577CE1FFE025C8B CRC64;
MSNLIGRWHQ YFLAHTINQP LGVKVIAMVT VVLVAFFAIP EERFTGDIYE VGDIASRNIK
SDRELLVIDE AATIQKRREA HEHAGLLFDH DRSVERSFVI AIEETFQAAR RAASAPEGSG
EVKELEAMLG RFHLQPEVLA HFQERQFSEA LEQRIKQCVG TAYGQGVYLP GSRSHVFDNA
FVRDISTGGV QRIVPERPPR TPSEVAAVID QHCQESAVVM FTMANLSPDI TFNERATITR
REELSQQVKP VYIVVRQGEM IVREGEIVDA MTRQKLNTLL RVKSPLEHWF SFMATLIMAS
ILILIPWKYF EKARKKIFNS SDRLYIFFTI LLGSIALVKL FSIIAAGLSF NLPYVSYDYL
IYAVPIAAGA MLVAILLDLH IAMIYTTVFS IICGVMVGHD ISFALYTFVS GLVAAYSSFS
FRNRMDLTFA ALWSSAAGAL VMVSILLFNG DLFSWGALWA FAFVFISGQI SMLLVMGLLP
IFESGFHVTS DLRLLELSNM GHPLLKQLIL RAPGTYHHSI IVGSLVEAAA EEIGVNPLLA
RVGAYYHDIG KMKKPEYFIE NQRGINRHDT LSPAMSSLVI TNHVKHGMEL AEEYSLPKSI
REIIQQHHGR TLIQYFYKKA LEGGEKVDDE KFRYAGPKPQ TRAAALVMLG DSCEAATRAL
SEPSHTRIQN LVQKIINNIF VDGQLDECEL TLKDIGMIAA SFTKTLTGIY HQRIEYPEDK
KEVQVPKEKP EKAPDAELDT RSRPGSGNPP IPTKKVPASI RHFTHQDVDI PGTPEADAKD
KGEKNGSNPQ YF
//
