ID E6WPN3_PSEUU Unreviewed; 335 AA.
AC E6WPN3;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Putative NAD(P)H dehydrogenase {ECO:0000313|EMBL:ADV25988.1};
GN OrderedLocusNames=Psesu_0126 {ECO:0000313|EMBL:ADV25988.1};
OS Pseudoxanthomonas suwonensis (strain 11-1).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Pseudoxanthomonas.
OX NCBI_TaxID=743721 {ECO:0000313|EMBL:ADV25988.1, ECO:0000313|Proteomes:UP000008632};
RN [1] {ECO:0000313|EMBL:ADV25988.1, ECO:0000313|Proteomes:UP000008632}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=11-1 {ECO:0000313|Proteomes:UP000008632};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Teshima H., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N.,
RA Ivanova N., Ovchinnikova G., Siebers A.K., Allgaier M., Thelen M.P.,
RA Hugenholtz P., Gladden J., Woyke T.;
RT "Complete sequence of Pseudoxanthomonas suwonensis 11-1.";
RL Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the 3-beta-HSD family.
CC {ECO:0000256|ARBA:ARBA00009219}.
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DR EMBL; CP002446; ADV25988.1; -; Genomic_DNA.
DR RefSeq; WP_013533818.1; NC_014924.1.
DR AlphaFoldDB; E6WPN3; -.
DR STRING; 743721.Psesu_0126; -.
DR KEGG; psu:Psesu_0126; -.
DR eggNOG; COG0451; Bacteria.
DR HOGENOM; CLU_007383_6_1_6; -.
DR OrthoDB; 3174087at2; -.
DR Proteomes; UP000008632; Chromosome.
DR GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43245; BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA; 1.
DR PANTHER; PTHR43245:SF51; SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY 42E, MEMBER 2; 1.
DR Pfam; PF01073; 3Beta_HSD; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000008632}.
FT DOMAIN 4..251
FT /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF01073"
SQ SEQUENCE 335 AA; 35849 MW; 7981271A98D22442 CRC64;
MKVLVTGGAG FLGQALCRAL LARGYEVHSF QRSHSPALEA MGVVQHRGDL ADAAAVARAV
AGKDAVLHNA AKAGAWGSYD SYHQANVVGT RNVIAACRAH GVGRLVYTST PSVTHRATHP
VEGLGAHEVP YGEDFQAPYA ATKAIAEQEA LAANGPELAV VALRPRLIWG PGDPQILPRL
VERAHAGRLR LVGDGSNRVD TTYIDNAAQA HLGALDHLAP GAACAGKAYF ISNGEPLPMR
EVLNRLLQAA GAPPVTRSIS FRTAYGIGAV CERLWPLLRL RSEPPMTRFL AEQLATAHWY
SMEPARRDFG YVPKVGFDEG IMRLKDSWQN TSSVT
//
