ID E6ZLZ3_SPORE Unreviewed; 594 AA.
AC E6ZLZ3;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 13-SEP-2023, entry version 38.
DE SubName: Full=Probable purine permease {ECO:0000313|EMBL:CBQ67459.1};
GN ORFNames=sr11410 {ECO:0000313|EMBL:CBQ67459.1};
OS Sporisorium reilianum (strain SRZ2) (Maize head smut fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Sporisorium.
OX NCBI_TaxID=999809 {ECO:0000313|EMBL:CBQ67459.1, ECO:0000313|Proteomes:UP000008867};
RN [1] {ECO:0000313|EMBL:CBQ67459.1, ECO:0000313|Proteomes:UP000008867}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SRZ2 {ECO:0000313|Proteomes:UP000008867};
RX PubMed=21148393; DOI=10.1126/science.1195330;
RA Schirawski J., Mannhaupt G., Muench K., Brefort T., Schipper K.,
RA Doehlemann G., Di Stasio M., Roessel N., Mendoza-Mendoza A., Pester D.,
RA Mueller O., Winterberg B., Meyer E., Ghareeb H., Wollenberg T.,
RA Muensterkoetter M., Wong P., Walter M., Stukenbrock E., Gueldener U.,
RA Kahmann R.;
RT "Pathogenicity determinants in smut fungi revealed by genome comparison.";
RL Science 330:1546-1548(2010).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR EMBL; FQ311430; CBQ67459.1; -; Genomic_DNA.
DR AlphaFoldDB; E6ZLZ3; -.
DR EnsemblFungi; CBQ67459; CBQ67459; sr11410.
DR VEuPathDB; FungiDB:sr11410; -.
DR eggNOG; ENOG502QQD4; Eukaryota.
DR HOGENOM; CLU_017959_7_0_1; -.
DR OrthoDB; 911690at2759; -.
DR Proteomes; UP000008867; Chromosome 1.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0071702; P:organic substance transport; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR InterPro; IPR006042; Xan_ur_permease.
DR NCBIfam; TIGR00801; ncs2; 1.
DR PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR PANTHER; PTHR42810:SF2; PURINE PERMEASE C1399.01C-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
DR PROSITE; PS01116; XANTH_URACIL_PERMASE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 98..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 135..156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 168..190
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 210..231
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 238..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 290..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 317..337
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 448..468
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 474..492
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 504..522
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 542..564
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 574..594
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..38
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 594 AA; 63260 MW; CA0A7EC6CD0AD494 CRC64;
MSKFATVTTQ PFAHPEPNTT SSHELSHDND ASSTSWRRSP RSHARKLGHR LSTRHGWFGD
YNFGALCLPR LFPWKSDSKL NVGAAESPFY GVHDDLPIAV AAICGFQHAL AMLGGLITPP
MIIASSLNLS GETSAYLISA SLITSGIISA VQQSAIPLPF GRQIGTGLLS VVGTSFTTLS
VTTSIFTNLY AEGICPLNAD GSRAACPDAY GYLLGTAAVC ALLEILLSFL PTRVLKRLFP
PIVTGSVVFF IGTKLIGESA MPSFGGGSSC HGTGKLCTGT DHRAYLWGDA HYLGLGFLAF
MTVVVTEIFG SPAMRNASIA IGLLFPLVVA GPLGYISSAP IEAAKPITFL WVETFKLRVY
GPAVLPLLAV YISLMMECIG DVTATSEVSR VEVDGEAYDR RIGSGVLVDG LAGVFSALFT
VPPLSVFAQN NGVIAITKCA NIQAGRWCSF WLILFGIIGK LAGCVRAIPQ PVLGGVLMIL
FGSIAVSGIK VLQNVTFTRR NRFILALSFA FGFGTLLVDD LFDELFTYHG GNKALKGFLD
SIVIVISTPF LISAIVGMIA NGVLPMDEED RELQRMRDAP ARRAQSSSDE KLSA
//
