ID E6ZQK7_SPORE Unreviewed; 180 AA.
AC E6ZQK7;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=60S ribosome subunit biogenesis protein NIP7 {ECO:0000256|PIRNR:PIRNR017190};
GN ORFNames=sr16016 {ECO:0000313|EMBL:CBQ69514.1};
OS Sporisorium reilianum (strain SRZ2) (Maize head smut fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Sporisorium.
OX NCBI_TaxID=999809 {ECO:0000313|EMBL:CBQ69514.1, ECO:0000313|Proteomes:UP000008867};
RN [1] {ECO:0000313|EMBL:CBQ69514.1, ECO:0000313|Proteomes:UP000008867}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SRZ2 {ECO:0000313|Proteomes:UP000008867};
RX PubMed=21148393; DOI=10.1126/science.1195330;
RA Schirawski J., Mannhaupt G., Muench K., Brefort T., Schipper K.,
RA Doehlemann G., Di Stasio M., Roessel N., Mendoza-Mendoza A., Pester D.,
RA Mueller O., Winterberg B., Meyer E., Ghareeb H., Wollenberg T.,
RA Muensterkoetter M., Wong P., Walter M., Stukenbrock E., Gueldener U.,
RA Kahmann R.;
RT "Pathogenicity determinants in smut fungi revealed by genome comparison.";
RL Science 330:1546-1548(2010).
CC -!- FUNCTION: Required for proper 27S pre-rRNA processing and 60S ribosome
CC subunit assembly. {ECO:0000256|PIRNR:PIRNR017190}.
CC -!- SUBUNIT: Interacts with pre-ribosome complex.
CC {ECO:0000256|PIRNR:PIRNR017190}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the NIP7 family. {ECO:0000256|ARBA:ARBA00009895,
CC ECO:0000256|PIRNR:PIRNR017190}.
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DR EMBL; FQ311437; CBQ69514.1; -; Genomic_DNA.
DR AlphaFoldDB; E6ZQK7; -.
DR EnsemblFungi; CBQ69514; CBQ69514; sr16016.
DR VEuPathDB; FungiDB:sr16016; -.
DR eggNOG; KOG3492; Eukaryota.
DR HOGENOM; CLU_097217_0_0_1; -.
DR OrthoDB; 177185at2759; -.
DR Proteomes; UP000008867; Chromosome 16.
DR GO; GO:0005737; C:cytoplasm; IEA:EnsemblFungi.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0030687; C:preribosome, large subunit precursor; IEA:EnsemblFungi.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:1902626; P:assembly of large subunit precursor of preribosome; IEA:EnsemblFungi.
DR GO; GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:EnsemblFungi.
DR CDD; cd21146; Nip7_N_euk; 1.
DR CDD; cd21151; PUA_Nip7-like; 1.
DR Gene3D; 3.10.450.220; -; 1.
DR Gene3D; 2.30.130.10; PUA domain; 1.
DR InterPro; IPR040598; NIP7_N.
DR InterPro; IPR002478; PUA.
DR InterPro; IPR015947; PUA-like_sf.
DR InterPro; IPR036974; PUA_sf.
DR InterPro; IPR016686; Ribosomal_synth_fac_NIP7.
DR InterPro; IPR005155; UPF0113_PUA.
DR PANTHER; PTHR23415:SF4; 60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 HOMOLOG; 1.
DR PANTHER; PTHR23415; CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7; 1.
DR Pfam; PF03657; UPF0113; 1.
DR Pfam; PF17833; UPF0113_N; 1.
DR PIRSF; PIRSF017190; Rbsml_synth_fac_NIP7; 1.
DR SMART; SM00359; PUA; 1.
DR SUPFAM; SSF88802; Pre-PUA domain; 1.
DR SUPFAM; SSF88697; PUA domain-like; 1.
DR PROSITE; PS50890; PUA; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR017190};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517,
KW ECO:0000256|PIRNR:PIRNR017190};
KW RNA-binding {ECO:0000256|PIRNR:PIRNR017190}.
FT DOMAIN 95..170
FT /note="PUA"
FT /evidence="ECO:0000259|SMART:SM00359"
SQ SEQUENCE 180 AA; 20320 MW; DECB3EE3D5CC8E22 CRC64;
MRPLTEEETK TLFEKLANYV GKNLVNLIDR ADDPHVFRLH RDRVYYVSES SMRLAISIAR
PNLMSLGTCF GKFSKTGKFR LHVTALDYLA QHAKYKVWIK PNGELPFLYG NHVVKAHLGR
ITDDTPEHAG VVVLGMSGTP LGFGVTARST VDTRKQDPTS IIVFHQADVG EYLRDEDTLF
//
