ID E6ZUC9_SPORE Unreviewed; 508 AA.
AC E6ZUC9;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 28-JUN-2023, entry version 36.
DE SubName: Full=Related to high-affinity nickel transport protein nic1 {ECO:0000313|EMBL:CBQ70836.1};
GN ORFNames=sr12497 {ECO:0000313|EMBL:CBQ70836.1};
OS Sporisorium reilianum (strain SRZ2) (Maize head smut fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Sporisorium.
OX NCBI_TaxID=999809 {ECO:0000313|EMBL:CBQ70836.1, ECO:0000313|Proteomes:UP000008867};
RN [1] {ECO:0000313|EMBL:CBQ70836.1, ECO:0000313|Proteomes:UP000008867}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SRZ2 {ECO:0000313|Proteomes:UP000008867};
RX PubMed=21148393; DOI=10.1126/science.1195330;
RA Schirawski J., Mannhaupt G., Muench K., Brefort T., Schipper K.,
RA Doehlemann G., Di Stasio M., Roessel N., Mendoza-Mendoza A., Pester D.,
RA Mueller O., Winterberg B., Meyer E., Ghareeb H., Wollenberg T.,
RA Muensterkoetter M., Wong P., Walter M., Stukenbrock E., Gueldener U.,
RA Kahmann R.;
RT "Pathogenicity determinants in smut fungi revealed by genome comparison.";
RL Science 330:1546-1548(2010).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the NiCoT transporter (TC 2.A.52) family.
CC {ECO:0000256|ARBA:ARBA00010892}.
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DR EMBL; FQ311441; CBQ70836.1; -; Genomic_DNA.
DR AlphaFoldDB; E6ZUC9; -.
DR EnsemblFungi; CBQ70836; CBQ70836; sr12497.
DR VEuPathDB; FungiDB:sr12497; -.
DR eggNOG; ENOG502QUYJ; Eukaryota.
DR HOGENOM; CLU_036094_1_0_1; -.
DR OrthoDB; 2725900at2759; -.
DR Proteomes; UP000008867; Chromosome 2.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0015099; F:nickel cation transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR004688; Ni/Co_transpt.
DR InterPro; IPR011541; Ni/Co_transpt_high_affinity.
DR PANTHER; PTHR31611; HIGH-AFFINITY NICKEL TRANSPORT PROTEIN NIC1; 1.
DR PANTHER; PTHR31611:SF0; HIGH-AFFINITY NICKEL TRANSPORT PROTEIN NIC1; 1.
DR Pfam; PF03824; NicO; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nickel {ECO:0000256|ARBA:ARBA00022596};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 23..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 108..134
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 146..168
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 250..275
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 302..321
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 417..438
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 474..496
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 366..410
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 366..389
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 390..409
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 508 AA; 55520 MW; 7EEE879C7FEF2575 CRC64;
MGGVWQRLCK WRCKWRPSRR PTLLLRCMLL IAAELAANAL LWVVAAIVFR HRSRFLTLSL
LAWTLGLRHA LDADHISVID NATRRIVSLN HSDSTPSRAA RPRRPVTCGL WFSLGHSTIV
VAVICAIAIS LGIVNRLGKV SSVGGIVGAA VSGSTLFLFA IVNSILLCQS VIATRKHRAA
RSHTHKDVDM DQTHSLQALP SCADPAAADK QHGEQQQQQH HDPVRDHRFR GIFTRLAYPL
FRLVDRPYKL YPIGVLFGLG FDTASSIALL GVAGATNSQV QDTSLESDQA ILPGDDANRS
DASIVLLALL FTTGMTLVDS LDSVLMINAY APGELLAPAP RQKDASKATS KLAWLKRLRF
LEDASSSEQQ TDLTAPSKAE IQNEELTSPS ELGEGKDSDN DDRAHTDHGT SSTLSHLLTL
LSILLAFAIS IITLMGLIGE NCDRCARAAA KQDETHHGGL EGRWWLFWQQ ANDASGIIGA
CIVGGFAAIL LLWYTAKAML RRYRRRAQ
//
