ID E6ZVG9_SPORE Unreviewed; 996 AA.
AC E6ZVG9;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE RecName: Full=VHS domain-containing protein {ECO:0000259|PROSITE:PS50179};
GN ORFNames=sr10928 {ECO:0000313|EMBL:CBQ71226.1};
OS Sporisorium reilianum (strain SRZ2) (Maize head smut fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Sporisorium.
OX NCBI_TaxID=999809 {ECO:0000313|EMBL:CBQ71226.1, ECO:0000313|Proteomes:UP000008867};
RN [1] {ECO:0000313|EMBL:CBQ71226.1, ECO:0000313|Proteomes:UP000008867}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SRZ2 {ECO:0000313|Proteomes:UP000008867};
RX PubMed=21148393; DOI=10.1126/science.1195330;
RA Schirawski J., Mannhaupt G., Muench K., Brefort T., Schipper K.,
RA Doehlemann G., Di Stasio M., Roessel N., Mendoza-Mendoza A., Pester D.,
RA Mueller O., Winterberg B., Meyer E., Ghareeb H., Wollenberg T.,
RA Muensterkoetter M., Wong P., Walter M., Stukenbrock E., Gueldener U.,
RA Kahmann R.;
RT "Pathogenicity determinants in smut fungi revealed by genome comparison.";
RL Science 330:1546-1548(2010).
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DR EMBL; FQ311442; CBQ71226.1; -; Genomic_DNA.
DR AlphaFoldDB; E6ZVG9; -.
DR EnsemblFungi; CBQ71226; CBQ71226; sr10928.
DR VEuPathDB; FungiDB:sr10928; -.
DR eggNOG; ENOG502S1ZS; Eukaryota.
DR HOGENOM; CLU_288886_0_0_1; -.
DR OrthoDB; 1383625at2759; -.
DR Proteomes; UP000008867; Chromosome 20.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR GO; GO:0007015; P:actin filament organization; IEA:InterPro.
DR GO; GO:0006897; P:endocytosis; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:UniProt.
DR GO; GO:0007034; P:vacuolar transport; IEA:UniProt.
DR CDD; cd16980; VHS_Lsb5; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR045007; LSB5.
DR InterPro; IPR002014; VHS_dom.
DR PANTHER; PTHR47789; LAS SEVENTEEN-BINDING PROTEIN 5; 1.
DR PANTHER; PTHR47789:SF2; VHS DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00790; VHS; 1.
DR SMART; SM00288; VHS; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR PROSITE; PS50179; VHS; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}.
FT DOMAIN 400..522
FT /note="VHS"
FT /evidence="ECO:0000259|PROSITE:PS50179"
FT REGION 1..369
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 545..651
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 824..920
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 961..996
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 778..805
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 45..68
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 78..126
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 224..253
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 292..308
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 545..573
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 586..651
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 829..853
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 862..920
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 966..980
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 996 AA; 107953 MW; 5664BE74E35F005F CRC64;
MKKFFKSKEA GTITPLPPTS PPASGPHSFG TPRLFDEYQA RVASHSSDSH RPLSLQTPSS
NSSRPPRDSA DDLSYAHNYS PPPSSRQRRS QQPGASPRKN RFSNQVADTA YESYSDPNSA
HSQAYRPSYD GNHAADYDAR RSQLSLPPPP PHASARMSSS GMAAFSPPKS LRPAHPPAHH
RRDNSLGMGV ASGAAYTNGS ADFNYAHRSP AAKPASADAA WAAPRHRRSQ DSDNSDRAHR
YDDRDDADDA DDGRTPTASS AARSAAYPVY SGADGDDAAG GEVLISQGRY EETTLRELDG
KDKGKAKKLF AFATSSSKDK KAKQDRDRAA ASSSPAPRAS RDRDDARLLS PPMDSRSLSA
QERSKEGWMD RWNKRAHQQQ AARVQDKEAE EAIAARIGWI CAHAYDEHDW MQILPVIDMV
GHSDAASKEA ARALRKEFKY GSVDTQRRAV RVWALLTLNG SDRFRLQVAS KRFLEAIEET
VASSKTPLSV KETMLRVLGV LAFEFRGDAE LVSVTKCWNR VKPSDRPKDG EPLENDLFEF
RLPQQRAAVQ QQQQQQQQPA QRRVSQRRSQ PPPRQGAGNG DMFEHQPSFA SRTQPSVPAS
LQPQSQPPLR QQQPQQQQAW PRSNLPDSNS HPRTAAFTAP VDHATNGSTG TDIVSNLEAA
AAPMDSRSAS YRSSADSSFG GTPHADIVTL DEDVRRLHEE CHIARSNAAV LLDTLLHEGL
HADTAELVDE FYAKVVRSQE LIASQVAWAS AQADRVKAGG ETREEALLAD LLEAHGRTSE
AVRAVDDARR RIEEEEAERR VTERSKVEVR LDRSALVLEG RGLLGHASGS RSPSPNAAVA
RGSTFSQPST ALPPRISRPL PVPRSDQSSD SNTSTHSFAP IAASLTASTH STTSSSHSLP
PISANSGSGG RSPLPLTPTL NIDTVHAMQV EGEGEEDEMQ TPVVPSAKAL GKRRAVSVRY
PTPPVGAVGG VPPPLPPHPM GTRGVLDGVG GLRLGE
//
