ID E6ZXA2_SPORE Unreviewed; 541 AA.
AC E6ZXA2;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Related to CDC20-cell division control protein {ECO:0000313|EMBL:CBQ71859.1};
GN ORFNames=sr12715 {ECO:0000313|EMBL:CBQ71859.1};
OS Sporisorium reilianum (strain SRZ2) (Maize head smut fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Sporisorium.
OX NCBI_TaxID=999809 {ECO:0000313|EMBL:CBQ71859.1, ECO:0000313|Proteomes:UP000008867};
RN [1] {ECO:0000313|EMBL:CBQ71859.1, ECO:0000313|Proteomes:UP000008867}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SRZ2 {ECO:0000313|Proteomes:UP000008867};
RX PubMed=21148393; DOI=10.1126/science.1195330;
RA Schirawski J., Mannhaupt G., Muench K., Brefort T., Schipper K.,
RA Doehlemann G., Di Stasio M., Roessel N., Mendoza-Mendoza A., Pester D.,
RA Mueller O., Winterberg B., Meyer E., Ghareeb H., Wollenberg T.,
RA Muensterkoetter M., Wong P., Walter M., Stukenbrock E., Gueldener U.,
RA Kahmann R.;
RT "Pathogenicity determinants in smut fungi revealed by genome comparison.";
RL Science 330:1546-1548(2010).
CC -!- SIMILARITY: Belongs to the WD repeat CDC20/Fizzy family.
CC {ECO:0000256|ARBA:ARBA00006445}.
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DR EMBL; FQ311452; CBQ71859.1; -; Genomic_DNA.
DR AlphaFoldDB; E6ZXA2; -.
DR EnsemblFungi; CBQ71859; CBQ71859; sr12715.
DR VEuPathDB; FungiDB:sr12715; -.
DR eggNOG; KOG0305; Eukaryota.
DR HOGENOM; CLU_014831_6_0_1; -.
DR OrthoDB; 20041at2759; -.
DR Proteomes; UP000008867; Chromosome 3.
DR GO; GO:0005680; C:anaphase-promoting complex; IEA:EnsemblFungi.
DR GO; GO:1990333; C:mitotic checkpoint complex, CDC20-MAD2 subcomplex; IEA:EnsemblFungi.
DR GO; GO:0034399; C:nuclear periphery; IEA:EnsemblFungi.
DR GO; GO:0010997; F:anaphase-promoting complex binding; IEA:EnsemblFungi.
DR GO; GO:1990757; F:ubiquitin ligase activator activity; IEA:EnsemblFungi.
DR GO; GO:0031145; P:anaphase-promoting complex-dependent catabolic process; IEA:EnsemblFungi.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007094; P:mitotic spindle assembly checkpoint signaling; IEA:EnsemblFungi.
DR GO; GO:1905786; P:positive regulation of anaphase-promoting complex-dependent catabolic process; IEA:EnsemblFungi.
DR GO; GO:0045842; P:positive regulation of mitotic metaphase/anaphase transition; IEA:EnsemblFungi.
DR GO; GO:0040020; P:regulation of meiotic nuclear division; IEA:EnsemblFungi.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR024977; Apc4-like_WD40_dom.
DR InterPro; IPR033010; Cdc20/Fizzy.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19918; CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED; 1.
DR PANTHER; PTHR19918:SF68; FI02843P; 1.
DR Pfam; PF12894; ANAPC4_WD40; 1.
DR Pfam; PF00400; WD40; 3.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000313|EMBL:CBQ71859.1};
KW Cell division {ECO:0000313|EMBL:CBQ71859.1};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT DOMAIN 252..293
FT /note="Anaphase-promoting complex subunit 4-like WD40"
FT /evidence="ECO:0000259|Pfam:PF12894"
FT REPEAT 257..291
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 341..382
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 476..509
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 88..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 172..197
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 173..190
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 541 AA; 57846 MW; 0BDACC087195EA8D CRC64;
MDSPLKDVSA NLRDMKLGTS PSKGSGLKAN SARLGLSRKD RLDSVPSASA DLKVGITRDW
QGPDKALKPK VAASISRGDR YIPNRELKRS TTPHSHVDGD GDTIRSQMSG DATDPNIAAN
IAAANANPTD LDGHPSFEDS VSAEMGQRIL SFSAAPPSSL ANPDVRSRYA MTKPKSTMPS
SLQSAGRRRI PTTPERTLDA PSMVGDYYYN LLDWSSTNMV AVALQTGLWI WNGNTGDASA
LLDTSTQAEK VGGGGLITGL RWDADGNILA VGLEGGFVQI WDVESSTRMR TLKPSGDGGA
DHASVNVAAW APDGTLNAGF QSGIIREYDV RERDAVTRTL EKAHHGPVCG MEWRSDSALM
ASGGNDNVVK VWDRRTSVAK MRKENHQAAV KALAWCPHNL SLLATGGGTS DRNIHFWNTT
QNSRTMTIST GAQITSLHWA PHYREIVSTH GLGTTESSKG LLNIWSHPSG TKVGEIEAHE
KRVLHSSLSP DGEVLATVSD DEELKLWRIF EKPAEASKGA KAAGGFGTHS AGGGLNVRTL
R
//
