ID E7A2S4_SPORE Unreviewed; 1291 AA.
AC E7A2S4;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=VASt domain-containing protein {ECO:0000259|PROSITE:PS51778};
GN ORFNames=sr14372 {ECO:0000313|EMBL:CBQ73781.1};
OS Sporisorium reilianum (strain SRZ2) (Maize head smut fungus).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Sporisorium.
OX NCBI_TaxID=999809 {ECO:0000313|EMBL:CBQ73781.1, ECO:0000313|Proteomes:UP000008867};
RN [1] {ECO:0000313|EMBL:CBQ73781.1, ECO:0000313|Proteomes:UP000008867}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SRZ2 {ECO:0000313|Proteomes:UP000008867};
RX PubMed=21148393; DOI=10.1126/science.1195330;
RA Schirawski J., Mannhaupt G., Muench K., Brefort T., Schipper K.,
RA Doehlemann G., Di Stasio M., Roessel N., Mendoza-Mendoza A., Pester D.,
RA Mueller O., Winterberg B., Meyer E., Ghareeb H., Wollenberg T.,
RA Muensterkoetter M., Wong P., Walter M., Stukenbrock E., Gueldener U.,
RA Kahmann R.;
RT "Pathogenicity determinants in smut fungi revealed by genome comparison.";
RL Science 330:1546-1548(2010).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the YSP2 family.
CC {ECO:0000256|ARBA:ARBA00006582}.
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DR EMBL; FQ311473; CBQ73781.1; -; Genomic_DNA.
DR EnsemblFungi; CBQ73781; CBQ73781; sr14372.
DR VEuPathDB; FungiDB:sr14372; -.
DR eggNOG; KOG1032; Eukaryota.
DR HOGENOM; CLU_265742_0_0_1; -.
DR OrthoDB; 45896at2759; -.
DR Proteomes; UP000008867; Chromosome 8.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0043226; C:organelle; IEA:UniProt.
DR CDD; cd13220; PH-GRAM_GRAMDC; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR004182; GRAM.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR031968; VASt.
DR PANTHER; PTHR23319:SF4; AT22714P-RELATED; 1.
DR PANTHER; PTHR23319; UNCHARACTERIZED; 1.
DR Pfam; PF02893; GRAM; 1.
DR Pfam; PF16016; VASt; 1.
DR SMART; SM00568; GRAM; 1.
DR PROSITE; PS51778; VAST; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00022989};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 855..1026
FT /note="VASt"
FT /evidence="ECO:0000259|PROSITE:PS51778"
FT REGION 1..428
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 459..531
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 763..802
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 822..846
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1045..1086
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..19
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 83..105
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 154..193
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 220..239
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 271..301
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 348..378
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 402..419
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 461..475
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 500..514
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 516..531
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1291 AA; 136313 MW; 44481B94AEA11439 CRC64;
MSSFKNIFRN SSKDGSIASP SSAKDHKRAK SQQTASSSQL DHLAADSSYT VGGAFPSKNG
SVPVSPFSAP VKLPAIDVTD LSDLDHPQQS PAVSSVSTLK AEESSGIHSD SPRRNSKGAA
AHRSMARPSS SSHAQWRSEP AHHAQPSANG KTSRRGSKVE KSEDGHGKPE PLNRHELMRR
AMATAQEFNE HDDDDTGSVF EDDHDHFSNS HHSHNHHNAH QSHPTNSTPV ASRQTPRQEF
PSDRPGDGNL SIDAFETGPS HVVGDANHAA ARPSSATSPS KSSSGPAMAP PTLTASATMP
TLVTPAPIRA EMPRSDSLEE MVNNPGNVYA PPHRFDSADP SRGPPQRATT LMEPSTSTQR
ASLQGMAKSA SSNALLRPTD IPSAADGSPR RPSDAGSVSG PFSRLRKNSD SSTVSKPGKG
KKSGPSAGIA GALASSGLAG MGVGHAGVFN HSQSALAEAE AASSKRKKET KRGSTSNADD
TAAGHVSGFQ GGIYRDPSTG SVIERDHEGN QFVPHRPQRD PSSSSFVSYD GSVTSDRSSV
SGLGAAAGFG AASAALLSSI GGVPGMPIIS PVLTPDGGHP IGGGGLVPPE AGGAGGAGDH
IDGETTWPED MGPQITGFAV ASSKRNHEFH QLFPQVPEDD YLIEDYGCAL VREILIQGRL
YISENHLCFK ANIFGWVTNL VLPFSEIISI EKRMTAFVIP NAIQIATLQS KHNFTSFLSR
DATYDLVVNI WKLSHPGVPI AAADQADLSD EYSEIEEDGD SLVTAGAAGG DQKGGDGEQQ
GKAGGESKPS KRARLKRKLK GTKTGVRDEN LAAVAAVAAR SGTPLLSQSR SPAPGGKRAA
HRKTTCPCEE KKEHFTSVVL DTTYPAVPEK IYNLLFTSTF MKEFWTDDQK LMDLQISEWS
PSSDNRNLLS RNISYIKPLA GGFGPKQTKC VLTDENLHVD FDNYVVTLTT TRTPDVPSGG
SFSVKTKTCI TWQGTGNVSH VYVTCQVEWS GRSMLKSIID KASLDGQMQY YKDLDEAVRK
YLTEHTSEFK EEGDDAAAVD EIARAATPGP NSRKGAAAAG DASGGSTSEK ATSGVGGAAG
GASQGGQGGM LDSITGPIMD AFGMLGDLLG GALEAVGIEG GASFKTLAFG FIIFILLLSN
IYTWRRSSPT SASSAHLVQH LDRMQAGGVN RGYFSDQGYY GPMSPRHTND GTRGPPVYER
VFAPNVYITP PGGNDATPDA IAKTVAEVLE KLYQQNVDRF WPGAGADADG DDPESVKRLM
AEAEAVFERL EKRLKAVGRD VKGKAEAKVE L
//
