ID E7A920_HELFC Unreviewed; 500 AA.
AC E7A920;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Mechanosensitive ion channel {ECO:0000313|EMBL:CBY82456.1};
GN OrderedLocusNames=Hfelis_03720 {ECO:0000313|EMBL:CBY82456.1};
OS Helicobacter felis (strain ATCC 49179 / NCTC 12436 / CS1).
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=936155 {ECO:0000313|EMBL:CBY82456.1, ECO:0000313|Proteomes:UP000007934};
RN [1] {ECO:0000313|Proteomes:UP000007934}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49179 / NCTC 12436 / CS1
RC {ECO:0000313|Proteomes:UP000007934};
RA Arnold A., Zigova Z., Lawley T., Falkow S., Bentley S., Aslett M.,
RA Muller A.;
RT "Comparative whole genome analysis of the carcinogenic bacterial pathogen
RT Helicobacter felis.";
RL Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CBY82456.1, ECO:0000313|Proteomes:UP000007934}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49179 / NCTC 12436 / CS1
RC {ECO:0000313|Proteomes:UP000007934};
RX PubMed=21402865;
RA Arnold I.C., Zigova Z., Holden M., Lawley T.D., Rad R., Dougan G.,
RA Falkow S., Bentley S.D., Muller A.;
RT "Comparative whole genome sequence analysis of the carcinogenic bacterial
RT model pathogen Helicobacter felis.";
RL Genome Biol. Evol. 3:302-308(2011).
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DR EMBL; FQ670179; CBY82456.1; -; Genomic_DNA.
DR RefSeq; WP_013468827.1; NC_014810.2.
DR AlphaFoldDB; E7A920; -.
DR STRING; 936155.HFELIS_03720; -.
DR GeneID; 36133881; -.
DR KEGG; hfe:HFELIS_03720; -.
DR eggNOG; COG0668; Bacteria.
DR HOGENOM; CLU_537133_0_0_7; -.
DR OrthoDB; 5329211at2; -.
DR Proteomes; UP000007934; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 2.30.30.60; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR PANTHER; PTHR30566:SF5; MECHANOSENSITIVE ION CHANNEL PROTEIN 1, MITOCHONDRIAL-RELATED; 1.
DR PANTHER; PTHR30566; YNAI-RELATED MECHANOSENSITIVE ION CHANNEL; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007934};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 221..241
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 261..279
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 302..385
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
SQ SEQUENCE 500 AA; 55965 MW; 3093B28F99C1C73B CRC64;
MGLRILVFLC LLCVGLYAQL DPSALKAQLE SLDKQLEPNT WVQKFKNFEH YQQLSLQIRH
LQGQLRTLKI KGGHGLETSA LEHNLQSLQH QQKLLESYKN PPFKELVEKP PILNTPTITN
PFAIIGGLSF LKSLQGHYKI MQANLGSLKH ALTLIQEKRA LLEQLNALSP KPQLSAQISQ
EQVKILEFQS AQNLLSASIE SYAKDVQATR ANLQDQIKDQ LFKLAWVVLA ALGSVLLAWL
LKRLSHKYLS GDERAYTINK AINFINANVI VLIFLFAYLE NISYLITFLG FASAGFAIAM
RDVFMSALGW LSILIKGSVH VGDRVGITKD GNTYVGDVLD ISMLNITILE DVTLTTYTKN
NGCAGRIIFV PNNYIFTGLF SNYTHLGLNA IWDSIDFLLP FGSNYQHAID IALKIATMHS
QPYSQATRTR LNKMRAKYAL RALDSEPKIA LMPEKEGLRL HVSYLVNAYD TLSLRSAIAL
EITQAFEQAD DIFITPKSAS
//
