ID E7EW65_HUMAN Unreviewed; 333 AA.
AC E7EW65;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Pregnancy specific beta-1-glycoprotein 9 {ECO:0000313|Ensembl:ENSP00000396753.2};
GN Name=PSG9 {ECO:0000313|Ensembl:ENSP00000396753.2};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000396753.2, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000396753.2, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15057824; DOI=10.1038/nature02399;
RA Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E.,
RA Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A.,
RA Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S.,
RA Carrano A.V., Caoile C., Chan Y.M., Christensen M., Cleland C.A.,
RA Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J.,
RA Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M.,
RA Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W.,
RA Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V.,
RA Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D.,
RA McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I.,
RA Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L.,
RA Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A.,
RA She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M.,
RA Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J.,
RA Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA Rubin E.M., Lucas S.M.;
RT "The DNA sequence and biology of human chromosome 19.";
RL Nature 428:529-535(2004).
RN [2] {ECO:0000313|Ensembl:ENSP00000396753.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the immunoglobulin superfamily. CEA family.
CC {ECO:0000256|ARBA:ARBA00038222}.
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DR EMBL; AC005392; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; NP_001288636.1; NM_001301707.1.
DR AlphaFoldDB; E7EW65; -.
DR SMR; E7EW65; -.
DR MassIVE; E7EW65; -.
DR PeptideAtlas; E7EW65; -.
DR ProteomicsDB; 18783; -.
DR Antibodypedia; 17573; 201 antibodies from 21 providers.
DR DNASU; 5678; -.
DR Ensembl; ENST00000443718.7; ENSP00000396753.2; ENSG00000183668.18.
DR GeneID; 5678; -.
DR UCSC; uc010xwm.3; human.
DR CTD; 5678; -.
DR HGNC; HGNC:9526; PSG9.
DR VEuPathDB; HostDB:ENSG00000183668; -.
DR GeneTree; ENSGT01100000263479; -.
DR OrthoDB; 3033616at2759; -.
DR BioGRID-ORCS; 5678; 8 hits in 1040 CRISPR screens.
DR ChiTaRS; PSG9; human.
DR GenomeRNAi; 5678; -.
DR Proteomes; UP000005640; Chromosome 19.
DR Bgee; ENSG00000183668; Expressed in placenta and 41 other cell types or tissues.
DR ExpressionAtlas; E7EW65; baseline and differential.
DR CDD; cd20948; IgC2_CEACAM5-like; 1.
DR CDD; cd05774; IgV_CEACAM_D1; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR44427; CARCINOEMBRYONIC ANTIGEN-RELATED CELL ADHESION MOLECULE 19; 1.
DR PANTHER; PTHR44427:SF14; PREGNANCY-SPECIFIC BETA-1-GLYCOPROTEIN 9; 1.
DR Pfam; PF13895; Ig_2; 1.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 3.
DR SMART; SM00408; IGc2; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR PROSITE; PS50835; IG_LIKE; 2.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|PeptideAtlas:E7EW65,
KW ECO:0007829|ProteomicsDB:E7EW65};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..34
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 35..333
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003219028"
FT DOMAIN 149..233
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 242..317
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 333 AA; 37724 MW; 0C33654D511F14F4 CRC64;
MGPLPAPSCT QRITWKGLLL TASLLNFWNP PTTAEVTIEA QPPKVSEGKD VLLLVHNLPQ
NLPGYFWYKG EMTDLYHYII SYIVDGKIII YGPAYSGRET VYSNASLLIQ NVTRKDAGTY
TLHIIKRGDE TREEIRHFTF TLYSKLPIPY ITINNLNPRE NKDVLAFTCE PKSENYTYIW
WLNGQSLPVS PGVKRPIENR ILILPSVTRN ETGPYQCEIR DRYGGLRSNP VILNVLYGPD
LPRIYPSFTY YRSGENLDLS CFTESNPPAE YFWTINGKFQ QSGQKLFIPQ ITRNHSGLYA
CSVHNSATGK EISKSMTVKV SGPCHGDLTE SQS
//
