ID E7F9M5_DANRE Unreviewed; 264 AA.
AC E7F9M5; A0A8M1Q7Q8;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE SubName: Full=Calcium channel, voltage-dependent, gamma subunit 6b {ECO:0000313|Ensembl:ENSDARP00000067740};
DE SubName: Full=Voltage-dependent calcium channel gamma-6 subunit-like {ECO:0000313|RefSeq:XP_001342833.1};
GN Name=cacng6b {ECO:0000313|Ensembl:ENSDARP00000067740,
GN ECO:0000313|RefSeq:XP_001342833.1,
GN ECO:0000313|ZFIN:ZDB-GENE-100922-272};
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955 {ECO:0000313|Ensembl:ENSDARP00000067740};
RN [1] {ECO:0000313|Ensembl:ENSDARP00000067740}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000067740};
RG Ensembl;
RL Submitted (JUL-2011) to UniProtKB.
RN [2] {ECO:0000313|Ensembl:ENSDARP00000067740, ECO:0000313|Proteomes:UP000000437}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000067740};
RX PubMed=23594743; DOI=10.1038/nature12111;
RG Genome Reference Consortium Zebrafish;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Eliott D.,
RA Threadgold G., Harden G., Ware D., Begum S., Mortimore B., Mortimer B.,
RA Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M.,
RA Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M.,
RA Glithero R., Howden P., Barker N., Lloyd C., Stevens C., Harley J.,
RA Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D.,
RA Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K.,
RA Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R.,
RA Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M.,
RA Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M.,
RA Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M.,
RA Woodmansey R., Clark G., Cooper J., Cooper J., Tromans A., Grafham D.,
RA Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J.,
RA Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I.,
RA Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M.,
RA Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M.,
RA Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G., Osoegawa K., Zhu B.,
RA Rapp A., Widaa S., Langford C., Yang F., Schuster S.C., Carter N.P.,
RA Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R.,
RA Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I.,
RA Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H.,
RA Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
RN [3] {ECO:0000313|RefSeq:XP_001342833.1}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|RefSeq:XP_001342833.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; CR848818; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_001342833.1; XM_001342797.6.
DR STRING; 7955.ENSDARP00000067740; -.
DR PaxDb; 7955-ENSDARP00000067740; -.
DR Ensembl; ENSDART00000067741; ENSDARP00000067740; ENSDARG00000046079.
DR Ensembl; ENSDART00000067741.6; ENSDARP00000067740.5; ENSDARG00000046079.6.
DR GeneID; 100003220; -.
DR KEGG; dre:100003220; -.
DR AGR; ZFIN:ZDB-GENE-100922-272; -.
DR CTD; 100003220; -.
DR ZFIN; ZDB-GENE-100922-272; cacng6b.
DR eggNOG; ENOG502QUPR; Eukaryota.
DR HOGENOM; CLU_093876_0_0_1; -.
DR OMA; FRNNQTC; -.
DR OrthoDB; 4230292at2759; -.
DR PhylomeDB; E7F9M5; -.
DR TreeFam; TF331651; -.
DR Reactome; R-DRE-5576892; Phase 0 - rapid depolarisation.
DR Reactome; R-DRE-5576893; Phase 2 - plateau phase.
DR Proteomes; UP000000437; Chromosome 16.
DR Bgee; ENSDARG00000046079; Expressed in muscle tissue and 7 other cell types or tissues.
DR GO; GO:1990454; C:L-type voltage-gated calcium channel complex; IBA:GO_Central.
DR GO; GO:0005246; F:calcium channel regulator activity; IBA:GO_Central.
DR GO; GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro.
DR GO; GO:1902514; P:regulation of calcium ion transmembrane transport via high voltage-gated calcium channel; IBA:GO_Central.
DR Gene3D; 1.20.140.150; -; 1.
DR InterPro; IPR004031; PMP22/EMP/MP20/Claudin.
DR InterPro; IPR005421; VDCC_g1su.
DR PANTHER; PTHR15025; VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-1 SUBUNIT-RELATED; 1.
DR PANTHER; PTHR15025:SF6; VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA-6 SUBUNIT; 1.
DR Pfam; PF13903; Claudin_2; 1.
DR PRINTS; PR01601; VDCCGAMMA1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000437};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 49..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 148..172
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..209
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 221..247
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 9..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 264 AA; 28855 MW; 07564AFAC673FC30 CRC64;
MWSNFFLQQD DDGRGGMGAL GGAGSKSGRT GKRARPPRMS DSEEGKIKLA FFLVLIGVTL
TVLGMGTEFW VELSQPKHFR NNQTCEMAHY GLWKSCVRTL WVTDIDPERE SCGPAELPGE
SNCTYFKFYT SGENAVIFKK TTQKSLHIAG AMLALLSLFM MVMGSVCITM SISKSVPFFL
KPATICFVCS GILVLLSIIV FHQSILALLA SDHSIPLHHE LSWSVACVGS SGAILIIGGL
IFLLLSLPYN PLEKCFRQQS SSDA
//
