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Database: UniProt
Entry: E7FEA4_DANRE
LinkDB: E7FEA4_DANRE
Original site: E7FEA4_DANRE 
ID   E7FEA4_DANRE            Unreviewed;       242 AA.
AC   E7FEA4;
DT   08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT   08-MAR-2011, sequence version 1.
DT   10-APR-2019, entry version 59.
DE   SubName: Full=Ring finger protein 166 {ECO:0000313|Ensembl:ENSDARP00000105686};
GN   Name=rnf166 {ECO:0000313|Ensembl:ENSDARP00000105686,
GN   ECO:0000313|ZFIN:ZDB-GENE-061121-1};
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Danio.
OX   NCBI_TaxID=7955 {ECO:0000313|Ensembl:ENSDARP00000105686, ECO:0000313|Proteomes:UP000000437};
RN   [1] {ECO:0000313|Ensembl:ENSDARP00000105686}
RP   IDENTIFICATION.
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000105686};
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
RN   [2] {ECO:0000313|Ensembl:ENSDARP00000105686, ECO:0000313|Proteomes:UP000000437}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000105686,
RC   ECO:0000313|Proteomes:UP000000437};
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C.,
RA   Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L.,
RA   McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C.,
RA   Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T.,
RA   Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T.,
RA   Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F.,
RA   Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H.,
RA   Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J.,
RA   Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P.,
RA   Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G.,
RA   Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D.,
RA   Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K.,
RA   Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C.,
RA   Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J.,
RA   Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA   Saunders D., Wallis J., Babbage A., Hammond S.,
RA   Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A.,
RA   Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D.,
RA   Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z.,
RA   Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J.,
RA   Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C.,
RA   Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C.,
RA   Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J.,
RA   Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C.,
RA   Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H.,
RA   Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J.,
RA   Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the
RT   human genome.";
RL   Nature 496:498-503(2013).
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DR   EMBL; CR547125; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_009301765.1; XM_009303490.2.
DR   STRING; 7955.ENSDARP00000105686; -.
DR   PaxDb; E7FEA4; -.
DR   Ensembl; ENSDART00000122603; ENSDARP00000105686; ENSDARG00000089538.
DR   GeneID; 100334524; -.
DR   KEGG; dre:100334524; -.
DR   CTD; 115992; -.
DR   ZFIN; ZDB-GENE-061121-1; rnf166.
DR   eggNOG; ENOG410IIQT; Eukaryota.
DR   eggNOG; ENOG4110WN4; LUCA.
DR   GeneTree; ENSGT00950000182909; -.
DR   InParanoid; E7FEA4; -.
DR   KO; K17044; -.
DR   OMA; NRSTFVC; -.
DR   OrthoDB; 1097558at2759; -.
DR   PhylomeDB; E7FEA4; -.
DR   TreeFam; TF331012; -.
DR   Proteomes; UP000000437; Chromosome 7.
DR   Bgee; ENSDARG00000089538; Expressed in 18 organ(s), highest expression level in brain.
DR   Gene3D; 3.30.40.10; -; 1.
DR   InterPro; IPR008598; Di19_Zn_binding_dom.
DR   InterPro; IPR034734; ZF_C2HC_RNF.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR017907; Znf_RING_CS.
DR   Pfam; PF05605; zf-Di19; 1.
DR   Pfam; PF18574; zf_C2HC_14; 1.
DR   SMART; SM00184; RING; 1.
DR   PROSITE; PS51803; ZF_C2HC_RNF; 1.
DR   PROSITE; PS00518; ZF_RING_1; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000000437};
KW   Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00175};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000437};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00175};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175}.
FT   DOMAIN       38     78       RING-type. {ECO:0000259|PROSITE:PS50089}.
FT   DOMAIN      103    122       C2HC RNF-type. {ECO:0000259|PROSITE:
FT                                PS51803}.
SQ   SEQUENCE   242 AA;  26882 MW;  5B9BB8EBBFB0C5A1 CRC64;
     MMAMFRSFVS AAQLRQHQQQ NGAAAAAPGE SLESQFSCPI CLEVYHKPVS IASCAHTFCG
     DCLQPCLQVT SPLCPLCRMP FDPKKVDKSS SVEKQLSSYK APCRGCSKKV TLVKMRSHIS
     SCTKVQEQMA NCPKFMPVVP TSQPIPSNIP NRSTFVCPYC GARNLDQQEL VKHCMENHRN
     DPNKVVCPVC SAMPWGDPSY KSSNFLQHLL HRHKFSYDTF VDYSIDEEAA LQAALTLSLS
     EN
//
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