ID E7FG02_DANRE Unreviewed; 649 AA.
AC E7FG02; A0A8M9P648;
DT 08-MAR-2011, integrated into UniProtKB/TrEMBL.
DT 08-MAR-2011, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=MAP7 domain-containing 2b {ECO:0000313|Ensembl:ENSDARP00000075049};
DE SubName: Full=MAP7 domain-containing protein 2 isoform X1 {ECO:0000313|RefSeq:XP_021325997.1};
GN Name=map7d2b {ECO:0000313|Ensembl:ENSDARP00000075049,
GN ECO:0000313|RefSeq:XP_021325997.1,
GN ECO:0000313|ZFIN:ZDB-GENE-091118-82};
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955 {ECO:0000313|Ensembl:ENSDARP00000075049};
RN [1] {ECO:0000313|Ensembl:ENSDARP00000075049}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000075049};
RG Ensembl;
RL Submitted (JUL-2011) to UniProtKB.
RN [2] {ECO:0000313|Ensembl:ENSDARP00000075049, ECO:0000313|Proteomes:UP000000437}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000075049};
RX PubMed=23594743; DOI=10.1038/nature12111;
RG Genome Reference Consortium Zebrafish;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Eliott D.,
RA Threadgold G., Harden G., Ware D., Begum S., Mortimore B., Mortimer B.,
RA Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M.,
RA Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M.,
RA Glithero R., Howden P., Barker N., Lloyd C., Stevens C., Harley J.,
RA Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D.,
RA Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K.,
RA Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R.,
RA Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M.,
RA Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M.,
RA Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M.,
RA Woodmansey R., Clark G., Cooper J., Cooper J., Tromans A., Grafham D.,
RA Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J.,
RA Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I.,
RA Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M.,
RA Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M.,
RA Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G., Osoegawa K., Zhu B.,
RA Rapp A., Widaa S., Langford C., Yang F., Schuster S.C., Carter N.P.,
RA Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R.,
RA Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I.,
RA Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H.,
RA Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
RN [3] {ECO:0000313|RefSeq:XP_021325997.1}
RP IDENTIFICATION.
RC STRAIN=Tuebingen {ECO:0000313|RefSeq:XP_021325997.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the MAP7 family.
CC {ECO:0000256|ARBA:ARBA00007525}.
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DR EMBL; BX649452; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CT574587; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_005162813.1; XM_005162756.3.
DR RefSeq; XP_021325997.1; XM_021470322.1.
DR PaxDb; 7955-ENSDARP00000075049; -.
DR Ensembl; ENSDART00000080602; ENSDARP00000075049; ENSDARG00000045316.
DR Ensembl; ENSDART00000080602.5; ENSDARP00000075049.3; ENSDARG00000045316.9.
DR GeneID; 100002505; -.
DR AGR; ZFIN:ZDB-GENE-091118-82; -.
DR CTD; 100002505; -.
DR ZFIN; ZDB-GENE-091118-82; map7d2b.
DR eggNOG; ENOG502QSSK; Eukaryota.
DR HOGENOM; CLU_017315_1_0_1; -.
DR OMA; KTPPCHA; -.
DR OrthoDB; 4247818at2759; -.
DR TreeFam; TF332273; -.
DR Proteomes; UP000000437; Chromosome 24.
DR Bgee; ENSDARG00000045316; Expressed in brain and 15 other cell types or tissues.
DR GO; GO:0015630; C:microtubule cytoskeleton; IBA:GO_Central.
DR GO; GO:0000226; P:microtubule cytoskeleton organization; IBA:GO_Central.
DR InterPro; IPR008604; MAP7_fam.
DR PANTHER; PTHR15073:SF3; MAP7 DOMAIN-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR15073; MICROTUBULE-ASSOCIATED PROTEIN; 1.
DR Pfam; PF05672; MAP7; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000000437}.
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 146..365
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 378..451
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 487..541
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 73..107
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 10..33
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 166..194
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 221..297
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 299..338
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 339..353
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 487..506
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 509..523
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 649 AA; 73746 MW; 4AC14E57E610937D CRC64;
MATVVENLID GGSKKDRIRQ AKERREEKDK SQALRERALW EKEQRAQQQY ERSVVERGRR
LEEQRHKEML RRSAVEEKRR QRVEDEKERL EALMRRSTNR NLQADQRPKR WTWCGPPGAC
EGDSKIAPPC PPASASLANE HAALTPASKS KNVQDFMILP DSPDSLLSRH LSSSSATLPN
MTEKASSSPH RSPYRASPSR AERKKVSASF CGPLDDSRGA ATTPKTPQTE KPEKSIAQTL
ADSTMKKLES PTTPTRSSSS TRKNPSTPKR SKSCKSRIQS PASPGQFPSS PMRHRATTPS
AENRIRDGEE KISEGSKGYS TLERKSSRTE RMPKSTSKEF GHNAESPVTP TGKAGTTDAE
EASRLLAERR RLARVLKEQE EKQRLEDERL RVEELQRQQE EERQRQEEEN RLAEEKRLRQ
EEQRCQREME DRHQKEQRWK ELQDDLERQR EEAVQRVHRE AERKRQEREL LKIQEEQERL
QRKKRIEEIM KRTRKPDGEK KEEAQMEVPS PISVSQSISP SPLETEGIRV INSPPKTASE
SPVICLEPLE AKSSLADDLS DGVQSMDVSP VSRDELVPEF SPISEISQNS MSSALGDILV
LTRQVSHPKV SAAPAFGDCN KNLIQDCSSA AIDSSLFQSL RPASDKLNI
//
