ID E7GAI0_9FIRM Unreviewed; 391 AA.
AC E7GAI0;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Integrase {ECO:0000313|EMBL:EFW04957.1};
DE Flags: Fragment;
GN ORFNames=HMPREF9488_01758 {ECO:0000313|EMBL:EFW04957.1};
OS Coprobacillus cateniformis.
OC Bacteria; Bacillota; Erysipelotrichia; Erysipelotrichales;
OC Coprobacillaceae; Coprobacillus.
OX NCBI_TaxID=100884 {ECO:0000313|EMBL:EFW04957.1, ECO:0000313|Proteomes:UP000003157};
RN [1] {ECO:0000313|EMBL:EFW04957.1, ECO:0000313|Proteomes:UP000003157}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=29_1 {ECO:0000313|EMBL:EFW04957.1,
RC ECO:0000313|Proteomes:UP000003157};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Daigneault M., Sibley C.D.,
RA White A., Strauss J., Allen-Vercoe E., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Alvarado L., Arachchi H.M.,
RA Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C., Freedman E.,
RA Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E.,
RA Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P., Mehta T.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., White J.,
RA Yandava C., Nusbaum C., Birren B.;
RT "The Genome Sequence of Coprobacillus sp. strain 29_1.";
RL Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the 'phage' integrase family.
CC {ECO:0000256|ARBA:ARBA00008857}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFW04957.1}.
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DR EMBL; ADKX01000031; EFW04957.1; -; Genomic_DNA.
DR RefSeq; WP_008788866.1; NZ_GL636579.1.
DR AlphaFoldDB; E7GAI0; -.
DR STRING; 100884.GCA_000269565_01854; -.
DR eggNOG; COG0582; Bacteria.
DR HOGENOM; CLU_671817_0_0_9; -.
DR Proteomes; UP000003157; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008907; F:integrase activity; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0075713; P:establishment of integrated proviral latency; IEA:UniProtKB-KW.
DR GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR GO; GO:0044826; P:viral genome integration into host DNA; IEA:UniProtKB-KW.
DR CDD; cd01189; INT_ICEBs1_C_like; 1.
DR Gene3D; 1.10.150.130; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 1.10.443.10; Intergrase catalytic core; 1.
DR InterPro; IPR044068; CB.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR InterPro; IPR011010; DNA_brk_join_enz.
DR InterPro; IPR013762; Integrase-like_cat_sf.
DR InterPro; IPR002104; Integrase_catalytic.
DR InterPro; IPR010998; Integrase_recombinase_N.
DR InterPro; IPR004191; Integrase_Tn916-type_DNA-bd_N.
DR PANTHER; PTHR30629; PROPHAGE INTEGRASE; 1.
DR PANTHER; PTHR30629:SF2; PROPHAGE INTEGRASE INTS-RELATED; 1.
DR Pfam; PF02920; Integrase_DNA; 1.
DR Pfam; PF00589; Phage_integrase; 1.
DR SUPFAM; SSF56349; DNA breaking-rejoining enzymes; 1.
DR SUPFAM; SSF54171; DNA-binding domain; 1.
DR PROSITE; PS51900; CB; 1.
DR PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE 3: Inferred from homology;
KW DNA integration {ECO:0000256|ARBA:ARBA00023195};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU01248}; Reference proteome {ECO:0000313|Proteomes:UP000003157};
KW Viral genome integration {ECO:0000256|ARBA:ARBA00023195};
KW Virus entry into host cell {ECO:0000256|ARBA:ARBA00023296}.
FT DOMAIN 73..157
FT /note="Core-binding (CB)"
FT /evidence="ECO:0000259|PROSITE:PS51900"
FT DOMAIN 180..387
FT /note="Tyr recombinase"
FT /evidence="ECO:0000259|PROSITE:PS51898"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EFW04957.1"
SQ SEQUENCE 391 AA; 45411 MW; 364B0E9A7E6B2406 CRC64;
DNKGRILHTG ESQRTDGKYL YKYVDAFGNT KYVYAWRLTP TDPTPKGKRE KPSLRELEQQ
IRRDIEDGID STGKKMTLCQ LYAKQNAQRA NVKKSTQKQR EQLMRLLKED KLGARSIDTI
KPSDAKEWAL RMKDKGFSYN TINNHKRSLK ASFYIAIQDD CVRKNPFDFK LSEVIENDTK
EKVALTEEQE QALLSFIKTD NVYHKHYDDV LILLKTGLRI SELCGLTVAD IDFKNEVVII
DHQLLKSKEQ GYYIETPKTK SGIRQVPLSR ETIQTFQRVM KKRPKAEPFV IDGRGNFLFV
NHKGKPKVAI DYNMLVVRMV KKYNKYHKDN PLPHITPHTL RHTFCTRLAS KNMNPKDLQY
IMGHSNISIT MNWYAHASID TAKSEVQRLI A
//
