ID E7GJC1_CLOSY Unreviewed; 444 AA.
AC E7GJC1;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Acetyl-CoA hydrolase {ECO:0000313|EMBL:EGA95110.1};
GN ORFNames=HMPREF9474_01014 {ECO:0000313|EMBL:EGA95110.1};
OS [Clostridium] symbiosum WAL-14163.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=742740 {ECO:0000313|EMBL:EGA95110.1, ECO:0000313|Proteomes:UP000002970};
RN [1] {ECO:0000313|EMBL:EGA95110.1, ECO:0000313|Proteomes:UP000002970}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WAL-14163 {ECO:0000313|EMBL:EGA95110.1,
RC ECO:0000313|Proteomes:UP000002970};
RA Earl A., Ward D., Feldgarden M., Gevers D., Finegold S.M., Summanen P.H.,
RA Molitoris D.R., Vaisanen M.L., Daigneault M., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA Heilman E., Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P.,
RA Mehta T., Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M.,
RA Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S.,
RA White J., Yandava C., Nusbaum C., Birren B.;
RT "The Genome Sequence of Clostridium symbiosum strain WAL-14163.";
RL Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the acetyl-CoA hydrolase/transferase family.
CC {ECO:0000256|ARBA:ARBA00009632}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGA95110.1}.
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DR EMBL; ADLQ01000026; EGA95110.1; -; Genomic_DNA.
DR RefSeq; WP_003499051.1; NZ_GL834306.1.
DR AlphaFoldDB; E7GJC1; -.
DR STRING; 1512.GCA_900049235_01107; -.
DR eggNOG; COG0427; Bacteria.
DR HOGENOM; CLU_030703_1_0_9; -.
DR Proteomes; UP000002970; Unassembled WGS sequence.
DR GO; GO:0008775; F:acetate CoA-transferase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006083; P:acetate metabolic process; IEA:InterPro.
DR Gene3D; 3.30.750.70; 4-hydroxybutyrate coenzyme like domains; 1.
DR Gene3D; 3.40.1080.20; Acetyl-CoA hydrolase/transferase C-terminal domain; 1.
DR Gene3D; 3.40.1080.10; Glutaconate Coenzyme A-transferase; 1.
DR InterPro; IPR026888; AcetylCoA_hyd_C.
DR InterPro; IPR038460; AcetylCoA_hyd_C_sf.
DR InterPro; IPR046433; ActCoA_hydro.
DR InterPro; IPR003702; ActCoA_hydro_N.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR PANTHER; PTHR21432:SF20; ACETYL-COA HYDROLASE; 1.
DR PANTHER; PTHR21432; ACETYL-COA HYDROLASE-RELATED; 1.
DR Pfam; PF13336; AcetylCoA_hyd_C; 1.
DR Pfam; PF02550; AcetylCoA_hydro; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000313|EMBL:EGA95110.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002970};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 6..190
FT /note="Acetyl-CoA hydrolase/transferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02550"
FT DOMAIN 278..438
FT /note="Acetyl-CoA hydrolase/transferase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13336"
SQ SEQUENCE 444 AA; 48837 MW; 914093AC258D6C08 CRC64;
MKNLKEIYSE KLMTADEALE LIKDGDYMFS AQAAGEPAEI LSHLGHLKCT GVKNTTLNTC
LPLQYYEAFK DPEMQGVMSH NGWFFSPGLR DAHKRKLVSA VPQSSTSVLR KALSRLEYEG
RRPVVLATVS PMDEHGYMSL SVSAIYERDL INYGALTILE VNPNFPRTFG DTQVHISEVD
ALVESNRPIP VSRLAPYTEV DAAIGKYVAS LVEDGSTIQL GIGNIPNAVA AELKNKKHLG
IHTEMFTETM VDLIECGAVD NSCKGLLDGY SVCSFTMGSQ RLYDYIDNNP AVLFKSCTFT
NDPYTIGRNN KFVSVNATLE IDLTGQCASE TVGYDQWSGT GGQSETVQGA QMSKGGKSII
AMHSTYKAKD EEGNEVLRSK IVPFLHEGAV VTTSRNDTDY VVTEYGIAWL RGLNVGQRAR
ALIAVAHPDF REELQAKAEE YGIW
//
