ID   E7GTX4_CLOSY            Unreviewed;       624 AA.
AC   E7GTX4;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   24-JAN-2024, entry version 41.
DE   RecName: Full=Rad50/SbcC-type AAA domain-containing protein {ECO:0000259|Pfam:PF13476};
GN   ORFNames=HMPREF9474_04369 {ECO:0000313|EMBL:EGA91761.1};
OS   [Clostridium] symbiosum WAL-14163.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=742740 {ECO:0000313|EMBL:EGA91761.1, ECO:0000313|Proteomes:UP000002970};
RN   [1] {ECO:0000313|EMBL:EGA91761.1, ECO:0000313|Proteomes:UP000002970}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WAL-14163 {ECO:0000313|EMBL:EGA91761.1,
RC   ECO:0000313|Proteomes:UP000002970};
RA   Earl A., Ward D., Feldgarden M., Gevers D., Finegold S.M., Summanen P.H.,
RA   Molitoris D.R., Vaisanen M.L., Daigneault M., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA   Arachchi H.M., Berlin A., Brown A., Chapman S.B., Chen Z., Dunbar C.,
RA   Freedman E., Gearin G., Gellesch M., Goldberg J., Griggs A., Gujja S.,
RA   Heilman E., Heiman D., Howarth C., Larson L., Lui A., MacDonald P.J.P.,
RA   Mehta T., Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M.,
RA   Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S.,
RA   White J., Yandava C., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Clostridium symbiosum strain WAL-14163.";
RL   Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EGA91761.1}.
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DR   EMBL; ADLQ01000102; EGA91761.1; -; Genomic_DNA.
DR   RefSeq; WP_003504803.1; NZ_GL834321.1.
DR   AlphaFoldDB; E7GTX4; -.
DR   STRING; 1512.GCA_900049235_04724; -.
DR   GeneID; 57968778; -.
DR   eggNOG; COG4717; Bacteria.
DR   HOGENOM; CLU_018670_0_0_9; -.
DR   Proteomes; UP000002970; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0006302; P:double-strand break repair; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR038729; Rad50/SbcC_AAA.
DR   PANTHER; PTHR41259:SF1; AAA_27 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR41259; DOUBLE-STRAND BREAK REPAIR RAD50 ATPASE, PUTATIVE-RELATED; 1.
DR   Pfam; PF13476; AAA_23; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002970};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        295..316
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        336..355
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          6..236
FT                   /note="Rad50/SbcC-type AAA"
FT                   /evidence="ECO:0000259|Pfam:PF13476"
FT   COILED          218..245
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   624 AA;  70852 MW;  49CDE428FC4EDE7E CRC64;
     MRFLDLYISG FGKFHNTSVS FEDGINIVYG KNEAGKSTIH TFIRGMLFGI ERQRGRAART
     DTYSKYEPWE NSGTYEGQLR LESDGIVYRI ERSFQKNKKE FIIVNETLGK EVEPTKAFMD
     ELLGGLSETV YNNTISISQL KSATEDGMIS ELKNYIANMN TSGNMALNIT KATNYLKGQK
     KQFETQLSPE AARTYTMLLS EIRNIEKEIS SPEYENQMQE YVKMRDSVKE EIELNQQEKD
     ELADKVLRGR QMLDDYEFSD EASISAYLNN AEEIYSCYND SKAVTQSGGG RMVPIILFLL
     AAAAAAGSGY FLYWYFYPYN TLLPVLPVKL KPYTTGMALA IGAAVLLAGG FFTLFRRKRL
     LKEAKLCTAT LSEIFKRHLG DSSISDEAME ALRSRLGEFT RLCQMMAKSE ETLKLQTEKI
     STLRERQNNC SEVIEKQQRI QWELEKKLEH LADCKDRAAA LKRIITENER LRQDIAAIDL
     AQETMQELSM SIRDSFGLYL NKTTSELISG ITGGIYTSIS IDENLNAFLN TKKKLVPLEQ
     VSSGTADQIY LALRLAAAKF IQGGEDRMPL VFDDSFVLYD DDRLRTALTW LSKACRGQII
     VFTCHKREGR ILKEAGVDYN LIEI
//