ID E7N8D0_9ACTO Unreviewed; 370 AA.
AC E7N8D0;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=NAD-dependent epimerase/dehydratase family protein {ECO:0000313|EMBL:EFW27568.1, ECO:0000313|EMBL:QCT34199.1};
GN ORFNames=FBF36_12720 {ECO:0000313|EMBL:QCT34199.1}, HMPREF9057_01037
GN {ECO:0000313|EMBL:EFW27568.1};
OS Actinomyces sp. oral taxon 171 str. F0337.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Actinomyces.
OX NCBI_TaxID=706439 {ECO:0000313|EMBL:EFW27568.1, ECO:0000313|Proteomes:UP000005722};
RN [1] {ECO:0000313|EMBL:EFW27568.1, ECO:0000313|Proteomes:UP000005722}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0337 {ECO:0000313|EMBL:EFW27568.1,
RC ECO:0000313|Proteomes:UP000005722};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA Chinwalla A., Mardis E.R., Wilson R.K.;
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:QCT34199.1, ECO:0000313|Proteomes:UP000310751}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0337 {ECO:0000313|EMBL:QCT34199.1,
RC ECO:0000313|Proteomes:UP000310751};
RA Collins A.J., Murugkar P., Chen T., Dewhirst F.E.;
RT "Saccharibacteria TM7 and host bacteria genomes.";
RL Submitted (APR-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC family. Dihydroflavonol-4-reductase subfamily.
CC {ECO:0000256|ARBA:ARBA00023445}.
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DR EMBL; AECW01000141; EFW27568.1; -; Genomic_DNA.
DR EMBL; CP040005; QCT34199.1; -; Genomic_DNA.
DR RefSeq; WP_009395036.1; NZ_GL637776.1.
DR AlphaFoldDB; E7N8D0; -.
DR eggNOG; COG0451; Bacteria.
DR HOGENOM; CLU_007383_9_2_11; -.
DR Proteomes; UP000005722; Unassembled WGS sequence.
DR Proteomes; UP000310751; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR001509; Epimerase_deHydtase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10366:SF564; 3BETA_HSD DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR10366; NAD DEPENDENT EPIMERASE/DEHYDRATASE; 1.
DR Pfam; PF01370; Epimerase; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 32..269
FT /note="NAD-dependent epimerase/dehydratase"
FT /evidence="ECO:0000259|Pfam:PF01370"
SQ SEQUENCE 370 AA; 39768 MW; 5F91B1A6051D343F CRC64;
MQSPAAHSSD NTDNFDSAIV LSGIPIDNSS PVMVTGATGY LGSWVTKGLL DAGVTVHAAV
RDPQNTSKVA HLNRMAEQAP GTLRLFTSDL LQPGSYNQAM EGCAVVIHTA SPFIRAVADP
QRDLVAPALQ GTRNVLAGVE RTPSVTRVVL TSSIAAMYGD AADIEGYPGR ILTETCWNTT
SSLSHEPYAY SKTLAEKEAW RLAAGQDRWK LVTVNPSMIL GPSLSSAPTS DSFSTIRMMI
DGTARLGAPR VGISVVDVRE VAQAHIAAAF LPEAHGRYIA SAEDTDIFAL TSTLIPRFGR
SLPLPRRALP RPVVVAIAPR LGQTRTYIRR NVGYAVRSDA SRSRLELGTR YRPVQASMEE
MVEQMLARQG
//
