ID   E7NQ46_TREPH            Unreviewed;       469 AA.
AC   E7NQ46;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   SubName: Full=Alpha-L-fucosidase {ECO:0000313|EMBL:EFW39308.1};
GN   ORFNames=HMPREF9554_00175 {ECO:0000313|EMBL:EFW39308.1};
OS   Treponema phagedenis F0421.
OC   Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Treponemataceae;
OC   Treponema.
OX   NCBI_TaxID=754027 {ECO:0000313|EMBL:EFW39308.1, ECO:0000313|Proteomes:UP000004157};
RN   [1] {ECO:0000313|EMBL:EFW39308.1, ECO:0000313|Proteomes:UP000004157}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F0421 {ECO:0000313|EMBL:EFW39308.1,
RC   ECO:0000313|Proteomes:UP000004157};
RA   Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA   Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA   Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA   Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA   Chinwalla A., Mardis E.R., Wilson R.K.;
RL   Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-
CC       1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the
CC       carbohydrate moieties of glycoproteins.
CC       {ECO:0000256|ARBA:ARBA00004071}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EFW39308.1}.
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DR   EMBL; AEFH01000013; EFW39308.1; -; Genomic_DNA.
DR   AlphaFoldDB; E7NQ46; -.
DR   STRING; 162.TPHV1_50004; -.
DR   eggNOG; COG3669; Bacteria.
DR   HOGENOM; CLU_002934_0_3_12; -.
DR   Proteomes; UP000004157; Unassembled WGS sequence.
DR   GO; GO:0004560; F:alpha-L-fucosidase activity; IEA:InterPro.
DR   GO; GO:0006004; P:fucose metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR016286; FUC_metazoa-typ.
DR   InterPro; IPR000933; Glyco_hydro_29.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR10030; ALPHA-L-FUCOSIDASE; 1.
DR   PANTHER; PTHR10030:SF46; ALPHA-L-FUCOSIDASE-RELATED; 1.
DR   Pfam; PF01120; Alpha_L_fucos; 1.
DR   PIRSF; PIRSF001092; Alpha-L-fucosidase; 1.
DR   PRINTS; PR00741; GLHYDRLASE29.
DR   SMART; SM00812; Alpha_L_fucos; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT   SITE            307
FT                   /note="May be important for catalysis"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001092-1"
SQ   SEQUENCE   469 AA;  54372 MW;  1DBCB566437C3683 CRC64;
     MLFYKTGEDF WRKIMEEPIM EKGVHAYSEE DRYVVPKSAA VRKHLEFFTG LKFGLMMHWA
     PGCQIATYES WPLCDDADDW SREDVIWTDD MEEFKHHYWN ANKTFNPIKF RPDHWADFAK
     RAGFKYLLFT TKHHDGFCMF DTQQTDYKIT ASDCPFSSNK RANIVQEVFN AFRAEGLAIS
     AYFSKPDWHS EYFWAPEMGK AETRNANYDI PSHPELWNKF VDFTHQQLRE ICSLYGHIDV
     LWLDGGQISP RIHNQDIRLG EIVEEIRNTT QPHLIVCDRT VGGEYENIIT PEQSIPSHYI
     GCPWEACITA GDYFSFHYED NFKSPHAIVR LLIEVVSKGG NLALNIPPQP DGQLPAKAMR
     NLLRVGEWLH IHGQAIYNTR GYPIAQEQKI FITEGSENVF VFYCYDENTP RLPRRVNIKL
     KDERAVQKIT CLRSGAAVSF IQNGKTLVIH TIELDPLGAN YADCLKLCF
//