ID E7NVP1_TREPH Unreviewed; 577 AA.
AC E7NVP1;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 24-JAN-2024, entry version 49.
DE SubName: Full=ABC transporter, ATP-binding protein {ECO:0000313|EMBL:EFW37353.1};
GN ORFNames=HMPREF9554_02154 {ECO:0000313|EMBL:EFW37353.1};
OS Treponema phagedenis F0421.
OC Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Treponemataceae;
OC Treponema.
OX NCBI_TaxID=754027 {ECO:0000313|EMBL:EFW37353.1, ECO:0000313|Proteomes:UP000004157};
RN [1] {ECO:0000313|EMBL:EFW37353.1, ECO:0000313|Proteomes:UP000004157}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0421 {ECO:0000313|EMBL:EFW37353.1,
RC ECO:0000313|Proteomes:UP000004157};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA Chinwalla A., Mardis E.R., Wilson R.K.;
RL Submitted (SEP-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFW37353.1}.
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DR EMBL; AEFH01000184; EFW37353.1; -; Genomic_DNA.
DR RefSeq; WP_002699565.1; NZ_GL638085.1.
DR AlphaFoldDB; E7NVP1; -.
DR STRING; 162.TPHV1_190023; -.
DR eggNOG; COG1132; Bacteria.
DR HOGENOM; CLU_000604_84_9_12; -.
DR Proteomes; UP000004157; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd07346; ABC_6TM_exporters; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039421; Type_1_exporter.
DR PANTHER; PTHR24221:SF397; ABC TRANSPORTER, ATP-BINDING TRANSMEMBRANE PROTEIN; 1.
DR PANTHER; PTHR24221; ATP-BINDING CASSETTE SUB-FAMILY B; 1.
DR Pfam; PF00664; ABC_membrane; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50929; ABC_TM1F; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:EFW37353.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 60..79
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 136..159
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 165..183
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 246..273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 20..306
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 338..572
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 577 AA; 64918 MW; 5B9BE73F8B2F4CC6 CRC64;
MKKYLKNRYS MSDVGAKNLV IAIFTHTLNN LSKILPPMFG FIFLDQFFGV YFGTPSTVQW
GMWQYLLTIG IMFIFMFIIG RIDYMRLYPV VYQESKNYRI DIANRLKKLP LAYFGKRDIA
DLSATIMSDL NVYEELFSHA VPQLYATVIS TIILSAMIIR YNVKLGLAVF CVIPFAYLIF
FVSRKFQKAS YRKGYAKKRE IYDSLQEGMD SIQEIKSYGM ENSFLENFKT KLKEEKKIKL
EGELSAGVFL NFAAIVLKIG IVAVALVGAK MFIAGEIPII TYAAYLMLSM SIYNPISDIF
NNLSMLLYLD TLVTRLKEIE GMPTQEGTEN FKPDNYDVGF ENVRFSYDDN FEVIRGVSFV
AKQGETTALV GPSGSGKTTL TKLAARFWDI NEGKITLGGT DISGVDPETL LKSFSIVFQD
VTLFNASIMD NIRIGRKDAS DEDVLRVSKL ARCDEFVQKL PDGYNTLIGE NGEKLSGGER
QRISIARAIL KDAPVILLDE ATASLDVENE SLIQEALSEL VRNKTVIIIA HRMRTVAGAD
KIVVLKNGKI EETGSPNELL EKNSLFKSMM EKQSLAV
//
