ID E8KKN2_9PAST Unreviewed; 400 AA.
AC E8KKN2;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 24-JAN-2024, entry version 51.
DE RecName: Full=Aromatic amino acid permease {ECO:0000256|RuleBase:RU367149};
GN ORFNames=HMPREF0027_2399 {ECO:0000313|EMBL:EFX90535.1};
OS Actinobacillus ureae ATCC 25976.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Actinobacillus.
OX NCBI_TaxID=887324 {ECO:0000313|EMBL:EFX90535.1, ECO:0000313|Proteomes:UP000005467};
RN [1] {ECO:0000313|EMBL:EFX90535.1, ECO:0000313|Proteomes:UP000005467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25976 {ECO:0000313|EMBL:EFX90535.1,
RC ECO:0000313|Proteomes:UP000005467};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in transporting aromatic amino acids across the
CC cytoplasmic membrane. {ECO:0000256|RuleBase:RU367149}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429, ECO:0000256|RuleBase:RU367149}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004429,
CC ECO:0000256|RuleBase:RU367149}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the amino acid/polyamine transporter 2 family.
CC Mtr/TnaB/TyrP permease subfamily. {ECO:0000256|ARBA:ARBA00005452,
CC ECO:0000256|RuleBase:RU367149}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFX90535.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AEVG01000156; EFX90535.1; -; Genomic_DNA.
DR RefSeq; WP_005625231.1; NZ_GL831081.1.
DR AlphaFoldDB; E8KKN2; -.
DR HOGENOM; CLU_038102_3_0_6; -.
DR Proteomes; UP000005467; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015173; F:aromatic amino acid transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR018227; Amino_acid_transport_2.
DR InterPro; IPR013059; Trp_tyr_transpt.
DR NCBIfam; TIGR00837; araaP; 1.
DR PANTHER; PTHR46997; LOW AFFINITY TRYPTOPHAN PERMEASE-RELATED; 1.
DR PANTHER; PTHR46997:SF1; LOW AFFINITY TRYPTOPHAN PERMEASE-RELATED; 1.
DR Pfam; PF03222; Trp_Tyr_perm; 1.
DR PRINTS; PR00166; AROAAPRMEASE.
PE 3: Inferred from homology;
KW Amino-acid transport {ECO:0000256|RuleBase:RU367149};
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519,
KW ECO:0000256|RuleBase:RU367149};
KW Cell membrane {ECO:0000256|RuleBase:RU367149};
KW Membrane {ECO:0000256|RuleBase:RU367149};
KW Transmembrane {ECO:0000256|RuleBase:RU367149};
KW Transmembrane helix {ECO:0000256|RuleBase:RU367149};
KW Transport {ECO:0000256|RuleBase:RU367149}.
FT TRANSMEM 7..28
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 34..57
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 83..101
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 121..139
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 151..171
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 186..203
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 223..243
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 283..308
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 320..339
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 345..363
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
FT TRANSMEM 370..392
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367149"
SQ SEQUENCE 400 AA; 43542 MW; 6D139DF55B63488A CRC64;
MKKQPTLFGG ACIIAGVCVG AGMLGLPTSG AGAWTMWSIL ALAFTMIVMT FSGWLLLDVY
KNYDLRASFN TVTKDLLGNK INALNNLAVY FVGGILLYAY TTASGGILEN LTKSAIDFGE
FGSRIWSALF VLIFSFFVWH STRLVDRISV LLIIFMALSF TFSISGLVSN IDSNILFDQQ
NDSGKYAKYA LAMLPVALTS FGYHHSVSSM RAYYGEVKKA KYAIAGGTLI ALVLYLLWVI
SIFGNLPRAQ FAPVIASNGD LDVLLNTIGE VVQSPYVKQA INAFSMAAIL SSFIGVGLGT
FDFLADFFKF DNSKSGRTKA WAVTFLPPLV FSLLSPLGFL KAIGYAGAVA TLWTCMIPAL
LVYKAKKGNL FMIGLVFLFG VCTAVFHFLS MYEMLPMFKS
//
