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Database: UniProt
Entry: E8LC46_9FIRM
LinkDB: E8LC46_9FIRM
Original site: E8LC46_9FIRM 
ID   E8LC46_9FIRM            Unreviewed;       715 AA.
AC   E8LC46;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   10-APR-2019, entry version 36.
DE   RecName: Full=Ferrous iron transport protein B {ECO:0000256|RuleBase:RU362098};
GN   Name=feoB {ECO:0000313|EMBL:EFY05550.1};
GN   ORFNames=HMPREF9443_00412 {ECO:0000313|EMBL:EFY05550.1};
OS   Phascolarctobacterium succinatutens YIT 12067.
OC   Bacteria; Firmicutes; Negativicutes; Acidaminococcales;
OC   Acidaminococcaceae; Phascolarctobacterium.
OX   NCBI_TaxID=626939 {ECO:0000313|EMBL:EFY05550.1, ECO:0000313|Proteomes:UP000004923};
RN   [1] {ECO:0000313|EMBL:EFY05550.1, ECO:0000313|Proteomes:UP000004923}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YIT 12067 {ECO:0000313|EMBL:EFY05550.1,
RC   ECO:0000313|Proteomes:UP000004923};
RA   Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B.,
RA   Courtney L., Fronick C., Harrison M., Strong C., Farmer C.,
RA   Delahaunty K., Markovic C., Hall O., Minx P., Tomlinson C.,
RA   Mitreva M., Hou S., Chen J., Wollam A., Pepin K.H., Johnson M.,
RA   Bhonagiri V., Zhang X., Suruliraj S., Warren W., Chinwalla A.,
RA   Mardis E.R., Wilson R.K.;
RL   Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable transporter of a GTP-driven Fe(2+) uptake
CC       system. {ECO:0000256|RuleBase:RU362098}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-
CC       like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
CC       {ECO:0000256|RuleBase:RU362098}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EFY05550.1}.
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DR   EMBL; AEVN01000015; EFY05550.1; -; Genomic_DNA.
DR   RefSeq; WP_009144803.1; NZ_GL830857.1.
DR   STRING; 626939.HMPREF9443_00412; -.
DR   EnsemblBacteria; EFY05550; EFY05550; HMPREF9443_00412.
DR   eggNOG; ENOG4105CE1; Bacteria.
DR   eggNOG; COG0370; LUCA.
DR   OrthoDB; 304844at2; -.
DR   BioCyc; GCF_000188175-HMP:HMPREF9443_RS01890-MONOMER; -.
DR   Proteomes; UP000004923; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015093; F:ferrous iron transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   CDD; cd01879; FeoB; 1.
DR   InterPro; IPR003373; Fe2_transport_prot-B.
DR   InterPro; IPR011640; Fe2_transport_prot_B_C.
DR   InterPro; IPR041069; FeoB_Cyto.
DR   InterPro; IPR030389; G_FEOB_dom.
DR   InterPro; IPR011642; Gate_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   Pfam; PF07664; FeoB_C; 1.
DR   Pfam; PF17910; FeoB_Cyto; 1.
DR   Pfam; PF02421; FeoB_N; 1.
DR   Pfam; PF07670; Gate; 2.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00437; feoB; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS51711; G_FEOB; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000004923};
KW   GTP-binding {ECO:0000256|RuleBase:RU362098};
KW   Ion transport {ECO:0000256|RuleBase:RU362098};
KW   Iron {ECO:0000256|RuleBase:RU362098};
KW   Iron transport {ECO:0000256|RuleBase:RU362098};
KW   Membrane {ECO:0000256|RuleBase:RU362098};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362098};
KW   Reference proteome {ECO:0000313|Proteomes:UP000004923};
KW   Transmembrane {ECO:0000256|RuleBase:RU362098};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU362098};
KW   Transport {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    280    298       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    392    410       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    422    446       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    452    472       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    515    534       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    546    565       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    604    627       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    647    667       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   TRANSMEM    679    698       Helical. {ECO:0000256|RuleBase:RU362098}.
FT   DOMAIN        3    164       FeoB-type G. {ECO:0000259|PROSITE:
FT                                PS51711}.
SQ   SEQUENCE   715 AA;  78053 MW;  432393A6FA5E76CE CRC64;
     MKQIKIALIG NPNCGKTTMF NDLTGSNQYV GNWPGVTVEK KEGGLKGHDD VIITDLPGIY
     SLSPYTLEEV VSRNYLLQND VDGVLNLVDG SNIERNLYLT TQVMEMGYPV TIALNMIDIV
     RKNGDKIDTA KLAAELGCEI VETSALQGEG TGEAAEKAIK AVGGAAPKYM RFCSEVEDAL
     TAIAREAGNK VHGISERWLL VKLFERDKKI AEALGLSEGE QAKIEEIVAA CEEALDDDAE
     SIITNERYNY IGELMSNAVV KGHTGLTISD KIDSIVTNRF LALPIFAIIM FLVYYIAVET
     IGTVVTDFTN DTLFGEWIQP WVQEHMEAAE CEDWLVSLVV DGIIGGIGAP IGFAPQMAIV
     FLLLSFLEDC GYMARVAFIM DRFFRQFGMS GKSFIPLLIS AGCGVPGIMA SRTIENETDR
     RLTIMTTTFV PCGAKLPVIA LLSGAIMGGD WYMAPIMYFV GFFAVITACI ILKKTELFAG
     DPAPFVMELP PYHLPAAKNV LLHTWERVAG FLKKAGTIIF LCCVVMWFLA SFGIDEGSVA
     MVDTEKSFVA YIGNGLAPIF APLGFDSWQA VAAAFSGFVA KESIVSMMAI LSGLAEAAED
     EPDLWTAVMA FFPSTVAAFS FLVFNLLDSP CLAAISTMSQ EMNSKKWTWA TILFQNLYAY
     SICLMVYQFG RVLVGGEAFS FGTGVAVVFL IAFLYLLFRP AKKYNKETVM SIDAK
//
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