ID   E8LE64_9FIRM            Unreviewed;       538 AA.
AC   E8LE64;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   27-MAR-2024, entry version 51.
DE   SubName: Full=5'-nucleotidase, C-terminal domain protein {ECO:0000313|EMBL:EFY04883.1};
GN   ORFNames=HMPREF9443_01135 {ECO:0000313|EMBL:EFY04883.1};
OS   Phascolarctobacterium succinatutens YIT 12067.
OC   Bacteria; Bacillota; Negativicutes; Acidaminococcales; Acidaminococcaceae;
OC   Phascolarctobacterium.
OX   NCBI_TaxID=626939 {ECO:0000313|EMBL:EFY04883.1, ECO:0000313|Proteomes:UP000004923};
RN   [1] {ECO:0000313|EMBL:EFY04883.1, ECO:0000313|Proteomes:UP000004923}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YIT 12067 {ECO:0000313|EMBL:EFY04883.1,
RC   ECO:0000313|Proteomes:UP000004923};
RA   Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA   Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA   Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA   Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA   Chinwalla A., Mardis E.R., Wilson R.K.;
RL   Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the 5'-nucleotidase family.
CC       {ECO:0000256|RuleBase:RU362119}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EFY04883.1}.
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DR   EMBL; AEVN01000045; EFY04883.1; -; Genomic_DNA.
DR   RefSeq; WP_009145500.1; NZ_GL830884.1.
DR   AlphaFoldDB; E8LE64; -.
DR   GeneID; 78525495; -.
DR   eggNOG; COG0737; Bacteria.
DR   HOGENOM; CLU_005854_7_3_9; -.
DR   OrthoDB; 7820733at2; -.
DR   Proteomes; UP000004923; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   GO; GO:0009166; P:nucleotide catabolic process; IEA:InterPro.
DR   CDD; cd00845; MPP_UshA_N_like; 1.
DR   Gene3D; 3.60.21.10; -; 1.
DR   Gene3D; 3.90.780.10; 5'-Nucleotidase, C-terminal domain; 1.
DR   InterPro; IPR008334; 5'-Nucleotdase_C.
DR   InterPro; IPR036907; 5'-Nucleotdase_C_sf.
DR   InterPro; IPR006179; 5_nucleotidase/apyrase.
DR   InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   PANTHER; PTHR11575:SF48; 5' NUCLEOTIDASE, ECTO-LIKE; 1.
DR   PANTHER; PTHR11575; 5'-NUCLEOTIDASE-RELATED; 1.
DR   Pfam; PF02872; 5_nucleotid_C; 1.
DR   Pfam; PF00149; Metallophos; 1.
DR   PRINTS; PR01607; APYRASEFAMLY.
DR   SUPFAM; SSF55816; 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain; 1.
DR   SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|RuleBase:RU362119};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362119};
KW   Reference proteome {ECO:0000313|Proteomes:UP000004923};
KW   Signal {ECO:0000256|RuleBase:RU362119}.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000256|RuleBase:RU362119"
FT   CHAIN           26..538
FT                   /evidence="ECO:0000256|RuleBase:RU362119"
FT                   /id="PRO_5039744161"
FT   DOMAIN          33..250
FT                   /note="Calcineurin-like phosphoesterase"
FT                   /evidence="ECO:0000259|Pfam:PF00149"
FT   DOMAIN          337..494
FT                   /note="5'-Nucleotidase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02872"
SQ   SEQUENCE   538 AA;  58791 MW;  D88D6BF5854010F1 CRC64;
     MKKFWKKTSL FLVTAAMTVS APLMAWALEH DIVILHTNDI HCGINDNIGF AGLAQIKKDA
     LARTPNVALV DAGDAIQGAP IGKLSRGLAV VDIMNYLGYD FCIPGNHEFD YGMDRFLELV
     PLQRAGYYCA NFVYAGNNKQ VLPGYKIMQY EDTKVAFVGA STPESLTTST PTFFQNEKGK
     YIYSFCEDKT GNKLYKQLQK NVDKARKDGA DYVFIVGHLG MDGTTPQWSS ESVAKNTQGV
     DAVIDGHSHE RFTRMVKNKV GKDVLLAQTG TKLKTVGELV ITPNGKLKSQ LITESNDKDA
     NIARVIAQEI KTYEPLLKQP VGEALVQLRS NDPATGGRIV RNRECSLGDF VADAYRAVLD
     CDVVLVNGGS IRNEIKTGVI SYNDLLEAFP FGNMCVVLEV NGQQILDALE MGAISYPEES
     GGFMQVSGLS YTIDSAVPSS IELDAKGNFV RVAGARRVSD VKIDGKPLDV KKKYTVGGTS
     YMLKSGGDGM TMFKGAHLVQ DEMMSDADTI MEYLQNHLNG KVGEQYANPY GDGRIVIK
//