ID E8LKU9_SUCHY Unreviewed; 564 AA.
AC E8LKU9;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Penicillin-binding protein, transpeptidase domain protein {ECO:0000313|EMBL:EFY06863.1};
GN ORFNames=HMPREF9444_01349 {ECO:0000313|EMBL:EFY06863.1};
OS Succinatimonas hippei (strain DSM 22608 / JCM 16073 / KCTC 15190 / YIT
OS 12066).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
OC Succinivibrionaceae; Succinatimonas.
OX NCBI_TaxID=762983 {ECO:0000313|EMBL:EFY06863.1, ECO:0000313|Proteomes:UP000018458};
RN [1] {ECO:0000313|EMBL:EFY06863.1, ECO:0000313|Proteomes:UP000018458}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22608 / JCM 16073 / KCTC 15190 / YIT 12066
RC {ECO:0000313|Proteomes:UP000018458};
RA Weinstock G., Sodergren E., Clifton S., Fulton L., Fulton B., Courtney L.,
RA Fronick C., Harrison M., Strong C., Farmer C., Delahaunty K., Markovic C.,
RA Hall O., Minx P., Tomlinson C., Mitreva M., Hou S., Chen J., Wollam A.,
RA Pepin K.H., Johnson M., Bhonagiri V., Zhang X., Suruliraj S., Warren W.,
RA Chinwalla A., Mardis E.R., Wilson R.K.;
RL Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFY06863.1}.
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DR EMBL; AEVO01000075; EFY06863.1; -; Genomic_DNA.
DR RefSeq; WP_009143537.1; NZ_GL831009.1.
DR AlphaFoldDB; E8LKU9; -.
DR STRING; 762983.HMPREF9444_01349; -.
DR GeneID; 78339774; -.
DR eggNOG; COG0768; Bacteria.
DR HOGENOM; CLU_009289_6_2_6; -.
DR OrthoDB; 9789078at2; -.
DR Proteomes; UP000018458; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.30.450.330; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Carboxypeptidase {ECO:0000256|ARBA:ARBA00022645};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022645};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Protease {ECO:0000256|ARBA:ARBA00022645};
KW Reference proteome {ECO:0000313|Proteomes:UP000018458};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 63..214
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 255..548
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 564 AA; 61873 MW; 0F89485CE06E28B1 CRC64;
MVYKPSLKNK TFTLSLFRVV IVWLVVLLSM AFLLTRLFWI QVLHPENLIK EGNSRVMRNY
SFEPARGLIT DRFGRILAIS VPVKTVYADA LELSRNKVTY DVEKIKKVAA ILELSPQEVF
SKIKNPKRRH VRLKQYLALD KAKELSDMRL PGIIINDNYQ RYYPTGAVNA HLVGLLNSEG
DGVYGVEQSF NSYLSAKALS RVAHKDLQGH IIENVATLEE GKAGGNLMLS VDDRLQTIAY
SSLQKAVTDH AAESGSAVMI DVKTGEVLAM VNYPSFDPND RSVFNSEKAK NRSITDILEP
GSTAKPIVAL AALEQNTVSW KEVIDTRPFV VDGKLIRDSH AMNYGTLTEI LKYSSNTGMA
HIALRTGPTK ILDTLRQFGL GHSTESGLVG EVNGTLNANR RFWSEIDKAT IGFGYGFAVT
PLQLSSAYAT LANYGLRLPV SILRLQQKPT ALQVGDVSEI KRIHAALETV VAQGTGGKAA
IDRYRIAGKT GTAKIAQAGG YSSRYFASFA GFAPISDPRF ALVVVIRAPQ KGSIYGGTVS
GPVFRDVMTR ALQLYNIAPD KADN
//
