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Database: UniProt
Entry: E8LQ32_9VIBR
LinkDB: E8LQ32_9VIBR
Original site: E8LQ32_9VIBR 
ID   E8LQ32_9VIBR            Unreviewed;       416 AA.
AC   E8LQ32;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   05-JUN-2019, entry version 45.
DE   RecName: Full=D-amino acid dehydrogenase {ECO:0000256|HAMAP-Rule:MF_01202};
DE            EC=1.4.99.- {ECO:0000256|HAMAP-Rule:MF_01202};
GN   Name=dadA {ECO:0000256|HAMAP-Rule:MF_01202};
GN   ORFNames=VIBR0546_18586 {ECO:0000313|EMBL:EGA67306.1};
OS   Vibrio brasiliensis LMG 20546.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales;
OC   Vibrionaceae; Vibrio; Vibrio oreintalis group.
OX   NCBI_TaxID=945543 {ECO:0000313|EMBL:EGA67306.1, ECO:0000313|Proteomes:UP000004371};
RN   [1] {ECO:0000313|EMBL:EGA67306.1, ECO:0000313|Proteomes:UP000004371}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG 20546 {ECO:0000313|EMBL:EGA67306.1,
RC   ECO:0000313|Proteomes:UP000004371};
RX   PubMed=21930677; DOI=10.1099/ijs.0.032375-0;
RA   Hoffmann M., Monday S.R., Allard M.W., Strain E.A., Whittaker P.,
RA   Naum M., McCarthy P.J., Lopez J.V., Fischer M., Brown E.W.;
RT   "Vibrio caribbeanicus sp. nov., isolated from the marine sponge
RT   Scleritoderma cyanea.";
RL   Int. J. Syst. Evol. Microbiol. 62:1736-1743(2012).
CC   -!- FUNCTION: Oxidative deamination of D-amino acids.
CC       {ECO:0000256|HAMAP-Rule:MF_01202, ECO:0000256|SAAS:SAAS00014764}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=A + a D-alpha-amino acid + H2O = a 2-oxocarboxylate + AH2
CC         + NH4(+); Xref=Rhea:RHEA:18125, ChEBI:CHEBI:13193,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:17499, ChEBI:CHEBI:28938,
CC         ChEBI:CHEBI:35179, ChEBI:CHEBI:59871;
CC         Evidence={ECO:0000256|HAMAP-Rule:MF_01202,
CC         ECO:0000256|SAAS:SAAS01189983};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence={ECO:0000256|HAMAP-
CC         Rule:MF_01202, ECO:0000256|SAAS:SAAS00344581};
CC   -!- SIMILARITY: Belongs to the DadA oxidoreductase family.
CC       {ECO:0000256|HAMAP-Rule:MF_01202, ECO:0000256|SAAS:SAAS00540638}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EGA67306.1}.
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DR   EMBL; AEVS01000014; EGA67306.1; -; Genomic_DNA.
DR   RefSeq; WP_006877941.1; NZ_AEVS01000014.1.
DR   STRING; 945543.VIBR0546_18586; -.
DR   EnsemblBacteria; EGA67306; EGA67306; VIBR0546_18586.
DR   eggNOG; ENOG4105MWK; Bacteria.
DR   eggNOG; COG0665; LUCA.
DR   Proteomes; UP000004371; Unassembled WGS sequence.
DR   GO; GO:0008718; F:D-amino-acid dehydrogenase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0019478; P:D-amino acid catabolic process; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.50.50.60; -; 2.
DR   HAMAP; MF_01202; DadA; 1.
DR   InterPro; IPR023080; DadA.
DR   InterPro; IPR006076; FAD-dep_OxRdtase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   Pfam; PF01266; DAO; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000004371};
KW   FAD {ECO:0000256|HAMAP-Rule:MF_01202, ECO:0000256|SAAS:SAAS00014763};
KW   Flavoprotein {ECO:0000256|HAMAP-Rule:MF_01202,
KW   ECO:0000256|SAAS:SAAS00014768};
KW   Oxidoreductase {ECO:0000256|HAMAP-Rule:MF_01202,
KW   ECO:0000256|SAAS:SAAS00423047, ECO:0000313|EMBL:EGA67306.1}.
FT   DOMAIN        2    397       DAO. {ECO:0000259|Pfam:PF01266}.
FT   NP_BIND       3     17       FAD. {ECO:0000256|HAMAP-Rule:MF_01202}.
SQ   SEQUENCE   416 AA;  45766 MW;  D04599A10BE0AC0F CRC64;
     MKVVILGSGV VGLTSAWYLS QAGFEVTVID RQARSAEETS FANAGQISYG YSSPWAAPGI
     PAKAIKWLFE EHAPLKIKPS LSPELIQWAS QMLVNCQLEK YRVNKSRMLT IANRSRECLA
     ELNRNYDLNY QGRTKGTLQI FRNPAQLKAV EKDIALLEES GTKYQLMNPA QCLVQEPGLA
     NMQGNLVGGL YLPDDETGDC QLFCQQLQQM AEQAGVTFLF NTTVDKLNSE NNQVVSVETS
     QGTIHADSYV IALGSYSKHL LAPLGIDIPV YPVKGYSLTL PVIDQQHAPN STIMDETYKV
     AVTRFEQRIR VAGTAELAGF DPALPDKRLA TLNHVVSNLF PQGVDLAQAE YWTGFRPMTP
     DGTPIIGQTK FSNLYTNTGH GTLGWTMACG SADILTRIIA SQGQQSFNEL SVERYS
//
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