ID   E8LSI2_9VIBR            Unreviewed;       644 AA.
AC   E8LSI2;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   24-JAN-2024, entry version 40.
DE   SubName: Full=PrkA family serine protein kinase {ECO:0000313|EMBL:EGA66429.1};
GN   ORFNames=VIBR0546_15856 {ECO:0000313|EMBL:EGA66429.1};
OS   Vibrio brasiliensis LMG 20546.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio; Vibrio oreintalis group.
OX   NCBI_TaxID=945543 {ECO:0000313|EMBL:EGA66429.1, ECO:0000313|Proteomes:UP000004371};
RN   [1] {ECO:0000313|EMBL:EGA66429.1, ECO:0000313|Proteomes:UP000004371}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG 20546 {ECO:0000313|EMBL:EGA66429.1,
RC   ECO:0000313|Proteomes:UP000004371};
RX   PubMed=21930677; DOI=10.1099/ijs.0.032375-0;
RA   Hoffmann M., Monday S.R., Allard M.W., Strain E.A., Whittaker P., Naum M.,
RA   McCarthy P.J., Lopez J.V., Fischer M., Brown E.W.;
RT   "Vibrio caribbeanicus sp. nov., isolated from the marine sponge
RT   Scleritoderma cyanea.";
RL   Int. J. Syst. Evol. Microbiol. 62:1736-1743(2012).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EGA66429.1}.
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DR   EMBL; AEVS01000045; EGA66429.1; -; Genomic_DNA.
DR   RefSeq; WP_006878778.1; NZ_AEVS01000045.1.
DR   AlphaFoldDB; E8LSI2; -.
DR   STRING; 945543.VIBR0546_15856; -.
DR   eggNOG; COG2766; Bacteria.
DR   OrthoDB; 9761914at2; -.
DR   Proteomes; UP000004371; Unassembled WGS sequence.
DR   GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR013153; Prk_AAA_dom.
DR   InterPro; IPR010650; PrkA_C_dom.
DR   InterPro; IPR016230; Ser_kinase_PrkA.
DR   PANTHER; PTHR30267; PROTEIN KINASE PRKA; 1.
DR   PANTHER; PTHR30267:SF2; PROTEIN PRKA; 1.
DR   Pfam; PF08298; AAA_PrkA; 1.
DR   Pfam; PF06798; PrkA; 1.
DR   PIRSF; PIRSF000549; Ser_prot_kin; 1.
DR   SMART; SM00763; AAA_PrkA; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:EGA66429.1};
KW   Transferase {ECO:0000313|EMBL:EGA66429.1}.
FT   DOMAIN          19..380
FT                   /note="PrkA AAA"
FT                   /evidence="ECO:0000259|SMART:SM00763"
SQ   SEQUENCE   644 AA;  74124 MW;  D356FF5FED347C27 CRC64;
     MSIFDHFQAR YEASKDEELS LQDFLGLCKD DKSAYANAAE RLLMAIGEPE VIDTAQDPHL
     SRIFSNRVIS RYQTFKDFYG MEDAIEQIVS YLKHAAQGLE ERKQILYLLG PVGGGKSSLA
     EKLKALMQQV PIYVLSANGE RSPVNDHPFC LFDVNEDGDL LKQEYGIEKR YIRSIMSPWA
     AKRLHEFGGD ISKFKVVKVR PSILDQLAIA KTEPGDENNQ DISSLVGKVD IRQLEHYSQD
     DPDAYSYSGA LCRANQGLME FVEMFKAPIK VLHPLLTATQ EGNYNGTEGL SALPFDGMIL
     AHSNESEWQT FRNNKNNEAF LDRVYIVKVP YCLRVSEEVK IYQKLLDHSE LSKAPCSPST
     LELLSQFSIL SRLKEPENSS IFSKMRVYDG ETLKDTDPKA KSYQEYRDFA GVDEGMSGLS
     TRFAFKILSR VFNFDQTEVA ANPVHLFYVI EQQIEREQFP QETAEKYLEF LKGYLVPRYV
     EFIGKEIQTA YLESYSEYGQ NIFDRYVTYA DFWIQDQEYR DPETGQLFDR SALNNELEKI
     EKTAGISNPK DFRNEIVNFV LRARANNNGT NPVWTSYEKL RTVIEKKMFS NTEELLPVIS
     FNTKTSSEDQ KKHDDFVARM MEKGYTEKQV RLLSEWYLRV RKSS
//