ID E8N2F9_ANATU Unreviewed; 292 AA.
AC E8N2F9;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=HIT family protein {ECO:0000313|EMBL:BAJ62765.1};
GN OrderedLocusNames=ANT_07310 {ECO:0000313|EMBL:BAJ62765.1};
OS Anaerolinea thermophila (strain DSM 14523 / JCM 11388 / NBRC 100420 /
OS UNI-1).
OC Bacteria; Chloroflexota; Anaerolineae; Anaerolineales; Anaerolineaceae;
OC Anaerolinea.
OX NCBI_TaxID=926569 {ECO:0000313|EMBL:BAJ62765.1, ECO:0000313|Proteomes:UP000008922};
RN [1] {ECO:0000313|EMBL:BAJ62765.1, ECO:0000313|Proteomes:UP000008922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14523 / JCM 11388 / NBRC 100420 / UNI-1
RC {ECO:0000313|Proteomes:UP000008922};
RA Narita-Yamada S., Kishi E., Watanabe Y., Takasaki K., Ankai A., Oguchi A.,
RA Fukui S., Takahashi M., Yashiro I., Hosoyama A., Sekiguchi Y., Hanada S.,
RA Fujita N.;
RT "Whole genome sequence of Anaerolinea thermophila UNI-1.";
RL Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; AP012029; BAJ62765.1; -; Genomic_DNA.
DR RefSeq; WP_013559158.1; NC_014960.1.
DR AlphaFoldDB; E8N2F9; -.
DR STRING; 926569.ANT_07310; -.
DR GeneID; 78349197; -.
DR KEGG; atm:ANT_07310; -.
DR eggNOG; COG0500; Bacteria.
DR eggNOG; COG0537; Bacteria.
DR HOGENOM; CLU_1045385_0_0_0; -.
DR InParanoid; E8N2F9; -.
DR OrthoDB; 155788at2; -.
DR Proteomes; UP000008922; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.30.428.10; HIT-like; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 2.
DR InterPro; IPR019808; Histidine_triad_CS.
DR InterPro; IPR001310; Histidine_triad_HIT.
DR InterPro; IPR011146; HIT-like.
DR InterPro; IPR036265; HIT-like_sf.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR42997:SF1; AP-4-A PHOSPHORYLASE; 1.
DR PANTHER; PTHR42997; HIT FAMILY HYDROLASE; 1.
DR Pfam; PF01230; HIT; 1.
DR Pfam; PF13489; Methyltransf_23; 1.
DR PRINTS; PR00332; HISTRIAD.
DR SUPFAM; SSF54197; HIT-like; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00892; HIT_1; 1.
DR PROSITE; PS51084; HIT_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008922}.
FT DOMAIN 169..276
FT /note="HIT"
FT /evidence="ECO:0000259|PROSITE:PS51084"
FT MOTIF 261..265
FT /note="Histidine triad motif"
FT /evidence="ECO:0000256|PIRSR:PIRSR601310-3,
FT ECO:0000256|PROSITE-ProRule:PRU00464"
FT ACT_SITE 263
FT /note="Tele-AMP-histidine intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR601310-1"
SQ SEQUENCE 292 AA; 33494 MW; FD3083E571ACC638 CRC64;
MNFVYQSPQN PNSHLTVKER NQASFPVRFL LQTNLIYGRV LDFGCGLGTD VEYLRNQGFE
VTGYDPYYFP EIPQGKFDTI LCLYVLNVLL PEEQAHVLMA ISELLQPDGR AYFAVRRDIQ
KNGFRFHVKR GVNVYQCNVR LPYRSILLTK NAEIYEYRHY NRLPHSNPHN CPFCAPEEER
ELLTESASAY AILDKFPVSP GHALIIPKQH LASYFDLSFH TKTALWLMTD RVKELVSEKY
HPDGFNIGIN IGTSAGQTIP HVHVHLIPRY AGDVENPRGG VRGVIPEKKD YL
//
