ID E8N6B0_ANATU Unreviewed; 685 AA.
AC E8N6B0;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Cytochrome c-type biogenesis protein CcmF {ECO:0000313|EMBL:BAJ63974.1};
GN Name=ccmF {ECO:0000313|EMBL:BAJ63974.1};
GN OrderedLocusNames=ANT_19480 {ECO:0000313|EMBL:BAJ63974.1};
OS Anaerolinea thermophila (strain DSM 14523 / JCM 11388 / NBRC 100420 /
OS UNI-1).
OC Bacteria; Chloroflexota; Anaerolineae; Anaerolineales; Anaerolineaceae;
OC Anaerolinea.
OX NCBI_TaxID=926569 {ECO:0000313|EMBL:BAJ63974.1, ECO:0000313|Proteomes:UP000008922};
RN [1] {ECO:0000313|EMBL:BAJ63974.1, ECO:0000313|Proteomes:UP000008922}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 14523 / JCM 11388 / NBRC 100420 / UNI-1
RC {ECO:0000313|Proteomes:UP000008922};
RA Narita-Yamada S., Kishi E., Watanabe Y., Takasaki K., Ankai A., Oguchi A.,
RA Fukui S., Takahashi M., Yashiro I., Hosoyama A., Sekiguchi Y., Hanada S.,
RA Fujita N.;
RT "Whole genome sequence of Anaerolinea thermophila UNI-1.";
RL Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for the biogenesis of c-type cytochromes. Possible
CC subunit of a heme lyase. {ECO:0000256|ARBA:ARBA00037230}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
CC {ECO:0000256|ARBA:ARBA00009186}.
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DR EMBL; AP012029; BAJ63974.1; -; Genomic_DNA.
DR RefSeq; WP_013560347.1; NC_014960.1.
DR AlphaFoldDB; E8N6B0; -.
DR STRING; 926569.ANT_19480; -.
DR GeneID; 78350312; -.
DR KEGG; atm:ANT_19480; -.
DR eggNOG; COG1138; Bacteria.
DR HOGENOM; CLU_015041_3_0_0; -.
DR InParanoid; E8N6B0; -.
DR OrthoDB; 9761451at2; -.
DR Proteomes; UP000008922; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0015232; F:heme transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.
DR InterPro; IPR032523; CcmF_C.
DR InterPro; IPR002541; Cyt_c_assembly.
DR InterPro; IPR003567; Cyt_c_biogenesis.
DR InterPro; IPR003568; Cyt_c_biogenesis_CcmF.
DR PANTHER; PTHR43653; CYTOCHROME C ASSEMBLY PROTEIN-RELATED; 1.
DR PANTHER; PTHR43653:SF1; CYTOCHROME C-TYPE BIOGENESIS PROTEIN CCMF; 1.
DR Pfam; PF16327; CcmF_C; 1.
DR Pfam; PF01578; Cytochrom_C_asm; 1.
DR PRINTS; PR01410; CCBIOGENESIS.
DR PRINTS; PR01411; CCMFBIOGNSIS.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cytochrome c-type biogenesis {ECO:0000256|ARBA:ARBA00022748};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008922};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..29
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 41..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 82..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 121..143
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 193..215
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 227..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 264..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 294..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 327..348
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 369..392
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 412..431
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 443..460
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 466..485
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 515..534
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 645..662
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 89..313
FT /note="Cytochrome c assembly protein"
FT /evidence="ECO:0000259|Pfam:PF01578"
FT DOMAIN 338..661
FT /note="Cytochrome c-type biogenesis protein CcmF C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF16327"
SQ SEQUENCE 685 AA; 76676 MW; F5D9A12361EA3762 CRC64;
MVANIGLGFL VLVFLVSLYG IIASIVGLRK KSFAWVESAR LAMLLTFPLI SVVVVSLLIL
LLTNRYEYSF VYGVTSRSMP LYLKVTALWG GQAGSLIFWS WLLAAFTTAV TLRQWDRDRE
FLPWVILTGL VTLAFFLSLS IFFENPFNRF WGTATGEVEA VFQPQGAIPL IPQDGRGLNP
LLRHPGMIIH PPMLYLGFVS FVVPYAFAIA ALVTGRTDDR WIRITRRWTL VAWLFLSLGL
VLGGRWAYDV LGWGGYWGWD PVEIAAFMPW LTGTAFLHSV MIQEKRGMFK RWNMILIIVT
YALVIFGTFL TRSGVLSSVH AFAQSAIGPM FFAFIGVTFV ISLSLLLYRW ADLADEGVLY
SLLSRESLFL LNNLLFIGIL IVCFSGVIFP LVSELLTGQK VTVGPPFYER ATGPLFAGLL
LLMGIAPLSA WGHSTVKTLG KALWKPALVS LLAIPLVLFL GVRNGWAILG FWLVVFTSSV
TLYEYGRAVL ARAKRTGESL WTSLWRLAQK NRRRYGGYTI HLGIVLMALG VIGIEMFQSE
TQATLRAGES VQLAGYTVTF RQLDEFDLPD GRNVARATVD VYRGGRYLGE LHPRRDYYWD
ANQPMTIPGT RSTMEDDLYV LLVDWQPISS QGATFKVFHN PLVNWMWFGS FVLILGTLIA
AWPDRDLEPQ RIVASSALPV HGRAS
//
