ID E8PQC7_THESS Unreviewed; 1111 AA.
AC E8PQC7;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Transcriptional activator domain protein {ECO:0000313|EMBL:ADW21786.1};
GN OrderedLocusNames=TSC_c11660 {ECO:0000313|EMBL:ADW21786.1};
OS Thermus scotoductus (strain ATCC 700910 / SA-01).
OC Bacteria; Deinococcota; Deinococci; Thermales; Thermaceae; Thermus.
OX NCBI_TaxID=743525 {ECO:0000313|EMBL:ADW21786.1, ECO:0000313|Proteomes:UP000008087};
RN [1] {ECO:0000313|Proteomes:UP000008087}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700910 / SA-01 {ECO:0000313|Proteomes:UP000008087};
RA Gounder K., Liesegang H., Brzuszkiewicz E., Wollherr A., Daniel R.,
RA Gottschalk G., van Heerden E., Litthauer D.;
RT "The genome sequence of Thermus scotoductus SA-01.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADW21786.1, ECO:0000313|Proteomes:UP000008087}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700910 / SA-01 {ECO:0000313|Proteomes:UP000008087};
RX PubMed=22115438; DOI=10.1186/1471-2164-12-577;
RA Gounder K., Brzuszkiewicz E., Liesegang H., Wollherr A., Daniel R.,
RA Gottschalk G., Reva O., Kumwenda B., Srivastava M., Bricio C.,
RA Berenguer J., van Heerden E., Litthauer D.;
RT "Sequence of the hyperplastic genome of the naturally competent Thermus
RT scotoductus SA-01.";
RL BMC Genomics 12:577-577(2011).
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DR EMBL; CP001962; ADW21786.1; -; Genomic_DNA.
DR RefSeq; WP_015717063.1; NC_014974.1.
DR AlphaFoldDB; E8PQC7; -.
DR STRING; 743525.TSC_c11660; -.
DR KEGG; tsc:TSC_c11660; -.
DR eggNOG; COG3629; Bacteria.
DR eggNOG; COG3899; Bacteria.
DR HOGENOM; CLU_004435_1_1_0; -.
DR Proteomes; UP000008087; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 4.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR16305:SF28; ADENYLATE CYCLASE 10; 1.
DR PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF13181; TPR_8; 1.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00028; TPR; 7.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 3.
DR PROSITE; PS50005; TPR; 2.
PE 4: Predicted;
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 113..250
FT /note="Bacterial transcriptional activator"
FT /evidence="ECO:0000259|SMART:SM01043"
FT REPEAT 166..199
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 701..734
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ SEQUENCE 1111 AA; 121432 MW; 4E54370D3F9D775D CRC64;
MARPLEAIEL RLLGGFAVRV GGCEVAQAAF ERRKAQSLLK LLSLQKGYRL HRDQVLEALW
PTPSPPAALS QLYKAVHQAR AALASAGLGL PPEELLALKG EVLSLQAPGG VISDLEAFEA
QARVALASGQ ITQLEQALAS YDELLPADRY EDWTLERREA LQELQVRLSL ALGQARLTQG
LLAEATEAFR TVLKLDPAHE EAHRGLMQIY ALQGSRLQMD RQYHRCRQAL AEELGVEPAP
ETEALYRRLL AAPLPPLAGE APVPASPTWP LAGREEELSQ MARALERLAL GREVVLGLEG
PPGIGKTRLA QEVLRLSRQR GYQTFLGTAH ATEGQLPYAP FVEVLRQALR TNPADSELLP
TELRAHIPEL PAGGAPVLTG DPLAAQGLLF AAVWRFLSRR ATDSPLVLVL EDLHNSDEGT
LHLFHYLARQ AVESPVLLLG TWRSEPKPPQ ALKQLIHSLE GLGLHSLSLK PLTQSAHRDL
LVKLLGGEVA PVLEEELYRL SEGNPLFALE VTRQLQESGQ LTRTDEGWHH TGLGSPPLPP
SLATLVGGWL VRLSPEALHL LQLIAVAGQT VPLAVLEAAV GPRLADTLEE ALTAHLLLEE
GLGYRFRHVL YREALYQGLS LARRSILHGE LARALEATYP SDPTPYTEAL AYHYRQAGKT
EQALGYLLKA GERATAVYDH AAALERYREA LGLELSGETR AGIWERIGDA HRATGNVHQA
LAAYREALEA TSSPAALYRK LALCAILATD MVSAKTYLHK AEAHLGDTPL ERAQLLLVWA
LYHWHWHEFE RAASEAHEVL NLAEAQGAQV EAQQACELLA LSYLPLGRWE EGLHYELKRG
LAGWSPEVAL ATDAHLCLWE YHVYGEDPYR QAQTFVHQVQ EHAQAMGNLR CVAVCHYALG
SMELLRANFH QAAHHLGRAL ELHQRIGSPA GEAYTRAREA LLHTARGELE AGWQAVQQGL
EAAQEAAVRD HCLARLYAAG LWNRLAAGDP GALHTLAEKS RSLEVSGAHC PVCSVQLFPA
LAAYHLCSGE LETALNYARK ATELAAAFQN QSGYAQARWM EGQVLAAQGR AEEAEVALAE
AASIFRTLGH AIDLIPRLSD CLPSGTPFLM P
//
