ID E8QX25_ISOPI Unreviewed; 373 AA.
AC E8QX25;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Radical SAM domain protein {ECO:0008006|Google:ProtNLM};
GN OrderedLocusNames=Isop_3507 {ECO:0000313|EMBL:ADV64064.1};
OS Isosphaera pallida (strain ATCC 43644 / DSM 9630 / IS1B).
OC Bacteria; Planctomycetota; Planctomycetia; Isosphaerales; Isosphaeraceae;
OC Isosphaera.
OX NCBI_TaxID=575540 {ECO:0000313|EMBL:ADV64064.1, ECO:0000313|Proteomes:UP000008631};
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 43644;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S.,
RA Kyrpides N., Mavromatis K., Pagani I., Ivanova N., Saunders E., Brettin T.,
RA Detter J.C., Han C., Tapia R., Land M., Hauser L., Markowitz V.,
RA Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Eisen J.A.;
RT "The complete sequence of chromosome of Isophaera pallida ATCC 43644.";
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADV64064.1, ECO:0000313|Proteomes:UP000008631}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43644 / DSM 9630 / IS1B
RC {ECO:0000313|Proteomes:UP000008631};
RX PubMed=21475588; DOI=10.4056/sigs.1533840;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Goker M., Cleland D., Saunders E., Lapidus A., Nolan M., Lucas S.,
RA Hammon N., Deshpande S., Cheng J.F., Tapia R., Han C., Goodwin L.,
RA Pitluck S., Liolios K., Pagani I., Ivanova N., Mavromatis K., Pati A.,
RA Chen A., Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D.,
RA Detter J.C., Beck B., Woyke T., Bristow J., Eisen J.A., Markowitz V.,
RA Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Isosphaera pallida type strain (IS1B).";
RL Stand. Genomic Sci. 4:63-71(2011).
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DR EMBL; CP002353; ADV64064.1; -; Genomic_DNA.
DR AlphaFoldDB; E8QX25; -.
DR STRING; 575540.Isop_3507; -.
DR KEGG; ipa:Isop_3507; -.
DR eggNOG; COG0535; Bacteria.
DR HOGENOM; CLU_050695_0_0_0; -.
DR InParanoid; E8QX25; -.
DR OrthoDB; 9810775at2; -.
DR Proteomes; UP000008631; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR024521; ArsS-like_C.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR026351; rSAM_ArsS-like.
DR NCBIfam; TIGR04167; rSAM_SeCys; 1.
DR PANTHER; PTHR43728:SF1; RADICAL SAM SUPERFAMILY PROTEIN-RELATED; 1.
DR PANTHER; PTHR43728; SLR0304 PROTEIN; 1.
DR Pfam; PF12345; DUF3641; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000008631};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 80..215
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|Pfam:PF04055"
FT DOMAIN 237..371
FT /note="Arsenosugar biosynthesis radical SAM protein ArsS-
FT like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12345"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 373 AA; 41009 MW; 0FEE59773658DF54 CRC64;
MTNPLPPPNL VRLESPAGFT TSGRHPSPRL SLARRAAPLA SPQEQIHLLN HTAAPEFAEV
LKARGLPPLK ASGVAVLQLN LGKLCNQTCS HCHVDAGPDR REVMSRAHLE YALEILKRTE
IGTVDLTGGA PEMNPHFRWF VAEARSLGRR VINRCNLTIL NAPGFTDLPE FLAAHQVEIV
ASLPCYLEEN TDRQRGDGVF VRSIAALKRL NALGYGQPAE RGGLPLTLVY NPIGPTLPPS
QNALETDYRR QLSERFGIVF TRLFTITNLP ISRFLEELVR EDQLDTYMSL LVNSFNPATV
EGVMCRETVS VSWDGRLFDC DFNQMLDLET DSAVPRRLDE FDAEALGSRR IVTGKHCFGC
TAGAGSSCQG ALV
//
