ID E8QXH0_ISOPI Unreviewed; 629 AA.
AC E8QXH0;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE SubName: Full=Bifunctional DNA primase/polymerase {ECO:0000313|EMBL:ADV63018.1};
GN OrderedLocusNames=Isop_2444 {ECO:0000313|EMBL:ADV63018.1};
OS Isosphaera pallida (strain ATCC 43644 / DSM 9630 / IS1B).
OC Bacteria; Planctomycetota; Planctomycetia; Isosphaerales; Isosphaeraceae;
OC Isosphaera.
OX NCBI_TaxID=575540 {ECO:0000313|EMBL:ADV63018.1, ECO:0000313|Proteomes:UP000008631};
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 43644;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S.,
RA Kyrpides N., Mavromatis K., Pagani I., Ivanova N., Saunders E., Brettin T.,
RA Detter J.C., Han C., Tapia R., Land M., Hauser L., Markowitz V.,
RA Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Eisen J.A.;
RT "The complete sequence of chromosome of Isophaera pallida ATCC 43644.";
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADV63018.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43644 {ECO:0000313|EMBL:ADV63018.1};
RX PubMed=21475588; DOI=10.4056/sigs.1533840;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Goker M., Cleland D., Saunders E., Lapidus A., Nolan M., Lucas S.,
RA Hammon N., Deshpande S., Cheng J.F., Tapia R., Han C., Goodwin L.,
RA Pitluck S., Liolios K., Pagani I., Ivanova N., Mavromatis K., Pati A.,
RA Chen A., Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D.,
RA Detter J.C., Beck B., Woyke T., Bristow J., Eisen J.A., Markowitz V.,
RA Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Isosphaera pallida type strain (IS1B).";
RL Stand. Genomic Sci. 4:63-71(2011).
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DR EMBL; CP002353; ADV63018.1; -; Genomic_DNA.
DR AlphaFoldDB; E8QXH0; -.
DR STRING; 575540.Isop_2444; -.
DR KEGG; ipa:Isop_2444; -.
DR eggNOG; COG3598; Bacteria.
DR HOGENOM; CLU_434624_0_0_0; -.
DR InParanoid; E8QXH0; -.
DR Proteomes; UP000008631; Chromosome.
DR CDD; cd04859; Prim_Pol; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR015330; DNA_primase/pol_bifunc_N.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014820; PriCT_1.
DR Pfam; PF13481; AAA_25; 1.
DR Pfam; PF08708; PriCT_1; 1.
DR Pfam; PF09250; Prim-Pol; 1.
DR SMART; SM00942; PriCT_1; 1.
DR SMART; SM00943; Prim-Pol; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56747; Prim-pol domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008631}.
FT DOMAIN 10..171
FT /note="DNA primase/polymerase bifunctional N-terminal"
FT /evidence="ECO:0000259|SMART:SM00943"
FT DOMAIN 193..258
FT /note="Primase C-terminal 1"
FT /evidence="ECO:0000259|SMART:SM00942"
FT REGION 536..559
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 629 AA; 68602 MW; 8794EA6E835E0147 CRC64;
MTPGELLTAA LRYAELGYRV FPCAPGNSTP LTDHGFLDAT TEVEQIERWW GQHPTANVAI
ATAGLLVVDL DPAEGNAANP WLKDDPDKRL DLAAAPTAMT PRGGRHHVFR KPAGKGWRCT
ASRLAPKVDT RTDGGYIIVP PSWRPDGAYS WVPGLELDGP PDRLPEPPPW LVALLDSLAQ
ETPTLAHVAA GGGQANPIPE GQRNATLARL GGNMRRVGMT LAEIAAALLQ TNKDRCFPPL
SPREVERIAA SVARYEPDQI ATAMAEGHWD QLMQVQAPQL APVSLADLTA RYPDLRRPVI
HGLLRQGETM NVISAPKIGK SWLVTDLALA VATGRPWLDT FACEAGDVLI IDNELHGETS
ANRIPKVAAA RQIGLGDVGG HVFVQNLRGH WQDIFSLGPY FRALEPGRFR VIILDAMYRF
MPREMDENDN GTMANVYNAI DRYADLLGCC FVLIHHTSKG NQSGKAITDV GAGAGSQSRA
TDTHLVLRPH EEDDVVVLEA AVRSWPPVLP RCLRWAFPVW TPADDLDPTL LRSERPRRAR
RAEADADEAE QPEPSWDAER FAAAFVTGTP KTRDAILAEA NAAGLSDWKA ERLLRRAEGL
GLVHRWASGR NRPSAYANVP QPASEDADQ
//
