ID E8R4S1_ISOPI Unreviewed; 609 AA.
AC E8R4S1;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Carboxyl-terminal protease {ECO:0000313|EMBL:ADV61667.1};
GN OrderedLocusNames=Isop_1079 {ECO:0000313|EMBL:ADV61667.1};
OS Isosphaera pallida (strain ATCC 43644 / DSM 9630 / IS1B).
OC Bacteria; Planctomycetota; Planctomycetia; Isosphaerales; Isosphaeraceae;
OC Isosphaera.
OX NCBI_TaxID=575540 {ECO:0000313|EMBL:ADV61667.1, ECO:0000313|Proteomes:UP000008631};
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 43644;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S.,
RA Kyrpides N., Mavromatis K., Pagani I., Ivanova N., Saunders E., Brettin T.,
RA Detter J.C., Han C., Tapia R., Land M., Hauser L., Markowitz V.,
RA Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Eisen J.A.;
RT "The complete sequence of chromosome of Isophaera pallida ATCC 43644.";
RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADV61667.1, ECO:0000313|Proteomes:UP000008631}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43644 / DSM 9630 / IS1B
RC {ECO:0000313|Proteomes:UP000008631};
RX PubMed=21475588; DOI=10.4056/sigs.1533840;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Goker M., Cleland D., Saunders E., Lapidus A., Nolan M., Lucas S.,
RA Hammon N., Deshpande S., Cheng J.F., Tapia R., Han C., Goodwin L.,
RA Pitluck S., Liolios K., Pagani I., Ivanova N., Mavromatis K., Pati A.,
RA Chen A., Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D.,
RA Detter J.C., Beck B., Woyke T., Bristow J., Eisen J.A., Markowitz V.,
RA Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Isosphaera pallida type strain (IS1B).";
RL Stand. Genomic Sci. 4:63-71(2011).
CC -!- SIMILARITY: Belongs to the peptidase S41A family.
CC {ECO:0000256|ARBA:ARBA00009179, ECO:0000256|RuleBase:RU004404}.
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DR EMBL; CP002353; ADV61667.1; -; Genomic_DNA.
DR RefSeq; WP_013563956.1; NC_014962.1.
DR AlphaFoldDB; E8R4S1; -.
DR KEGG; ipa:Isop_1079; -.
DR eggNOG; COG0793; Bacteria.
DR HOGENOM; CLU_479722_0_0_0; -.
DR InParanoid; E8R4S1; -.
DR OrthoDB; 9812068at2; -.
DR Proteomes; UP000008631; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00988; PDZ_CTP_protease; 1.
DR CDD; cd07560; Peptidase_S41_CPP; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 3.30.750.44; -; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR041489; PDZ_6.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR004447; Peptidase_S41A.
DR InterPro; IPR005151; Tail-specific_protease.
DR NCBIfam; TIGR00225; prc; 1.
DR PANTHER; PTHR32060:SF22; CARBOXYL-TERMINAL-PROCESSING PEPTIDASE 2, CHLOROPLASTIC-RELATED; 1.
DR PANTHER; PTHR32060; TAIL-SPECIFIC PROTEASE; 1.
DR Pfam; PF17820; PDZ_6; 1.
DR Pfam; PF03572; Peptidase_S41; 1.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00245; TSPc; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|RuleBase:RU004404};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Protease {ECO:0000256|RuleBase:RU004404, ECO:0000313|EMBL:ADV61667.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008631};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825,
KW ECO:0000256|RuleBase:RU004404}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 36..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 290..349
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 590..609
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 609 AA; 67921 MW; F3B0703B6EDFC65E CRC64;
MSGRHRERNI RRRRFGNTPA SLDQPGRFQR QGQGPFVWAA WWVVVSLLLP VGSPVPALAW
VQLDPAPVVS LPAGALAPAL PDDGESDEPT RLLRAGITLE RRRAWDEAVR HYTEASKRHP
DCADFQDRKR LCEIHARLNK RYRDRSFQND LLTLEPEVSQ ALYAEVLEQI ERHYVDVVSM
ERLVKRGIDH FDVALRDPVF VDRHLGHQPA ERIRLVRERL RAERQTVRVS TRREAIFEAH
RLVSMASRAL RLEPTPAMLE FIFGACDALD PHTTCLTPDR LNELFALIDG NFVGLGVDLK
YEQDALKLVG VLRGGPAAEA GLRPGDWIIA VDGRSLAKLD LDTAARTLEG PEGSSVELEI
RRAPGTIHRV RLVRRHVEIE SVAEVKIIDR SRGVGYIRLN GFQRTTLEEF QRAMRRLEQD
GMTALVLDLR DNPGGLLNVS IDLADLFLDR GRIVRTRGRA ADQTSDYIDR TPAVYRLPLA
VLIDRHSASA AEVLAGALKE NERALVVGET SYGKGSIQSI LPLRTVPVGL KLTTAVFHSP
LDHPYSGHGV VPNLMVRSNL KPTLSGESAG AADGTPAYDP IREAALRRLD DYPKLGPRPG
RAIRTQPGL
//
